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2篇 您的检索式:作者名="Bassem R Haddad"
    题名 作者 年代 出处 被引量
1Diagnosis of aneuploidy in archival, paraffin-embedded pregnancy-loss tissues by comparative genomic hybridization显示文摘Karen A Bell Peter G Van Deerlin Ronald F Feinberg Stanislas du Manoir Bassem R Haddad 2001Fertility and Sterility2001,,2:1
2在一个直肠的肿瘤和它的肺复发之间的基因错误的惹人注目的类似显示文摘 We are reporting the longest disease-free interval ever published for colorectal cancer, using gene profiling to confirm the linkage of the primary and metastasis. This rare case reports on a patient with late recurrence of colorectal cancer in the lung 19 years after its initial diagnosis. We used high-resolution array CGH(aCGH) to analyze the genetic aberrations of both the primary rectal and the recurrent metastatic lung lesions. Interestingly, we found striking similarities between the two lesions, despite the 19 years disease-free interval.In addition, most of the genes that were previously reported to be associated with a high recurrence score showed copy number gains by aCGH in one or both lesions. Our findings suggest that aCGH may be a helpful tool in analyzing the origin of metastatic lesions and reflect the need for a better understanding of the characteristics of the rectal tumors with a late recurrence potential.Osama E Rahma Mauricio Burotto Luisa Matos Do Canto Alexandre A Germanos Bassem R Haddad John L Marshall 2013World Journal of Gastrointestinal Oncology2013,5,11:0
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