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| 1 | Role of functional imaging in the development and refinement of invasive neuromodulation for psychiatric disorders显示文摘Deep brain stimulation(DBS) is emerging as a pow-erful tool for the alleviation of targeted symptoms in treatment-resistant neuropsychiatric disorders. Despite the expanding use of neuropsychiatric DBS, the mecha-nisms responsible for its effects are only starting to be elucidated. Several modalities such as quantitative elec-troencephalography as well a intraoperative recordings have been utilized to attempt to understand the under-pinnings of this new treatment modality, but functional imaging appears to offer several unique advantages. Functional imaging techniques like positron emission tomography, single photon emission computed tomog-raphy and functional magnetic resonance imaging have been used to examine the effects of focal DBS on activ-ity in a distributed neural network. These investigations are critical for advancing the field of invasive neuro-modulation in a safe and effective manner, particularly in terms of defining the neuroanatomical targets and refining the stimulation protocols. The purpose of this review is to summarize the current functional neuroim-aging findings from neuropsychiatric DBS implantation for three disorders: treatment-resistant depression, obsessive-compulsive disorder, and Tourette syndrome. All of the major targets will be discussed(Nucleus ac-cumbens, anterior limb of internal capsule, subcallosal cingulate, Subthalamic nucleus, Centromedial nucleus of the thalamus-Parafasicular complex, frontal pole, and dorsolateral prefrontal cortex). We will also address some apparent inconsistencies within this literature, and suggest potential future directions for this promis-ing area. | Nolan R Williams Joseph J Taylor Kayla Lamb Colleen A Hanlon E Baron Short Mark S George | 2014 | World Journal of Radiology2014，6，10： | 6 |
| 2 | NGF, DCX, and NSE upregulation correlates with severity and outcome of head trauma in children显示文摘 | A Chiaretti G Barone R Riccardi A Antonelli P Pezzotti O Genovese L Tortorolo G Conti | 2009 | Neurology2009，，7： | 3 |
| 3 | A Pooled Analysis of Advanced Colorectal Neoplasia Diagnoses After Colonoscopic Polypectomy显示文摘 | María Elena Martínez John A. Baron David A. Lieberman Arthur Schatzkin Elaine Lanza Sidney J. Winawer Ann G. Zauber Ruiyun Jiang Dennis J. Ahnen John H. Bond Timothy R. Church Douglas J. Robertson Stephanie A. Smith–Warner Elizabeth T. Jacobs David S. Alb | 2009 | Gastroenterology2009，，3： | 2 |
| 4 | Survival after inflammatory bowel disease-associated colorectal cancer in the Colon Cancer Family Registry显示文摘AIM: To investigate the survival of individuals with colorectal cancer (CRC) with inflammatory bowel disease (IBD-associated CRC) compared to that of individuals without IBD diagnosed with CRC. METHODS: Epidemiologic, clinical, and follow-up data were obtained from the Colon Cancer Family Registry (Colon CFR). IBD-associated cases were identified from self-report of physician diagnosis. For a subset of participants, medical records were examined to confirm self-report of IBD. Cox proportional hazards regression was applied to estimate adjusted hazard ratios (aHR) and 95%CI of mortality, comparing IBD-associated to non-IBD-associated CRC, adjusted for age at CRC diagnosis, sex, Colon CFR phase, and number of prior endoscopies. Following imputation to complete CRC stage information, adjustment for CRC stage was examined. RESULTS: A total of 7202 CRC cases, including 250 cases of IBD-associated CRC, were analyzed. Over a twelve year follow-up period following CRC diagnosis, 2013 and 74 deaths occurred among non-IBD associated CRC and IBD-associated CRC patients, respectively. The difference in survival between IBD-associated and non-IBD CRC cases was not statistically significant (aHR = 1.08; 95%CI: 0.85-1.36). However, the assumption of proportional hazards necessary for valid inference from Cox regression was not met over the entire follow-up period, and we therefore limited analyses to within five years after CRC diagnosis when the assumption of proportional hazards was met. Over this period, there was evidence of worse prognosis for IBD-associated CRC (aHR = 1.36; 95%CI: 1.05-1.76). Results were similar when adjusted for CRC stage, or restricted to IBD confirmed in medical records. CONCLUSION: These results support the hypothesis that IBD-associated CRC has a worse prognosis than non-IBD-associated CRC. | Scott V Adams Dennis J Ahnen John A Baron Peter T Campbell Steven Gallinger William M Grady Loic LeMarchand Noralane M Lindor John D Potter Polly A Newcomb | 2013 | World Journal of Gastroenterology2013，19，21： | 2 |
| 5 | Maxillary Alveolar Ridge Reconstruction With Nonvascularized Autogenous Block Bone:Clinical Results显示文摘 | Barone A Covani U | 2007 | Oral and Maxillofacial Surgery2007，65，10： | 1 |
| 6 | PCB Transport into Lake Sediments, Conceptal Model and Laboratory Simulation显示文摘 | Baron J A | 1988 | Environ Sci Technol1988，22，： | 1 |
| 7 | Improved detection of Vibrio cholerae in environmental water samples by culture on selective medium and colony hybridization assay with an oligonucleotide probe显示文摘 | Robert-Pilot A Baron S Lesne J | 2002 | FEMS Microbiol Ecol2002，40，3： | 1 |
| 8 | The moderator-mediator vairable distinction in social psychological research:conceptual,strategic,and statistical considerations显示文摘 | BARON R M KENNY D A | 1986 | J Pers Soc Psychol1986，51，6： | 1 |
| 9 | The moderator - mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations 显示文摘 | Baron R M Kenny D A | 1986 | Journal of Personality and Social Psychology1986，51，： | 1 |
| 10 | The moderator-mediator variable distinction in social psychological research: Concep- tual, strategic, and statistical considerations 显示文摘 | Baron R M Kenny D A | 1986 | Journal of Personality and Social Psychology1986，51，6： | 1 |
| 11 | Complicatons of ERCP 显示文摘 | J Shawn Mallery Todd H Baron Jason A Kom initz | 2003 | American Society For Gastrointestinal Endoscopy2003，57，6： | 1 |
| 12 | Guidelines for Conscious Sedation and Monitoring During Gastrointestinal Endoscopy显示文摘 | J.Patrick Waring Todd H Baron William K Hirota Jay L Goldstein Brian C Jacobson Jonathan A Leighton J.Shawn Mallery Douglas O Faigel | 2003 | Gastrointestinal Endoscopy2003，，3： | 1 |
| 13 | The moderator-mediator varia- ble distinction in social psychological research: Con- ceptual, strategic, and statistical considerations显示文摘 | Baron R M Kenny D A | 1986 | Journal of Personality and Social Psychology1986，51，6： | 1 |
| 14 | CtlP and MRN promote non - homologous end - joining of etoposide - induced DNA double - strand breaks in GI显示文摘 | Quennet V Beueher A Baron O | 2011 | Nucleic Acids Res2011，39，6： | 1 |
| 15 | The Shang ring device for adult male circumcision: a proof of voncept study in Kenya显示文摘 | Barone M A Masson P Li P S | 2011 | J Acquir Immune DeficSyndr2011，57，1： | 1 |
| 16 | The Moderator-Mediator Variable Distinction in Social Psychological Research:Conceptual, Strategic ,and Statistical Considerations显示文摘 | Baron R M kenny D A | 1986 | Journal of Per- sonality and Social Psychology1986，51，6： | 1 |
| 17 | Androgens inhibit aromatase expression through DAX - 1 : insights into the molecular link between hormone balance and Leydig cancer development显示文摘 | Maris P Campan A Barone I | 2015 | Endocrinology2015，156，4： | 1 |
| 18 | Medical tourism and health care outsourcing in a global world显示文摘 | Viladrich A Baron F R | 2012 | Advances in Medicine and Biology2012，61，1： | 1 |
| 19 | Opportunity recognition as the detection of meaningful patterns: Evidence from comparisons of novice and experienced entrepre- neurs显示文摘 | Baron R A Ensley M D | 2006 | Management Science2006，52，9： | 1 |
| 20 | Corrosion of amorphous and nanocrystalline Fe-basedalloys and its influence on their magnetic behavior显示文摘 | Baron A Szewieezek D Nawrat G | 2007 | Electrochimica Acta2007，52，： | 1 |
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