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| 1 | Cachexia and pancreatic cancer: Are there treatment options?显示文摘Cachexia is frequently described in patients with pancreatic ductal adenocarcinoma(PDAC)and is associated with reduced survival and quality of life.Unfortunately,the therapeutic options of this multi-factorial and complex syndrome are limited.This is due to the fact that,despite extensive preclinical and clinical research,the underlying pathological mechanisms leading to PDAC-associated cachexia are still not fully understood.Furthermore,there is still a lack of consensus on the definition of cachexia,which complicates the standardization of diagnosis and treatment as well as the analysis of the current literature.In order to provide an efficient therapy for cachexia,an early and reliable diagnosis and consistent monitoring is required,which can be challenging especially in obese patients.Although many substances have been tested in clinical and preclinical settings,so far none of them have been proven to have a long-term effect in ameliorating cancer-associated cachexia.However,recent studies have demonstrated that multidimensional therapeutic modalities are able to alleviate pancreatic cancerassociated cachexia and ultimately improve patients’outcome.In this current review,we propose a stepwise and pragmatic approach to facilitate and standardize the treatment of cachexia in pancreatic cancer patients.This strategy consists of nutritional,dietary,pharmacological,physical and psychological methods. | Tara C Mueller Marc A Burmeister Jeannine Bachmann Marc E Martignoni | 2014 | World Journal of Gastroenterology2014，20，28： | 3 |
| 2 | The EFSUMB Guidelines and Recommendations on the Clinical Practice of Contrast Enhanced Ultrasound (CEUS): Update 2011 on non-hepatic applications显示文摘 | F. Piscaglia C. Nols?e C. Dietrich D. Cosgrove O. Gilja M. Bachmann Nielsen T. Albrecht L. Barozzi M. Bertolotto O. Catalano M. Claudon D. Clevert J. Correas M. D'Onofrio F. Drudi J. Eyding M. Giovannini M. Hocke A. Ignee E. Jung A. Klauser N. Lassau E. L | 2012 | Ultraschall in Med2012，，01： | 2 |
| 3 | Time dependence of the expression of ICAM-1 (CD54)in human skin wounds 显示文摘 | Drebler J Bachmann L Mvller E | 1997 | Int J Legal Med1997，110，6： | 1 |
| 4 | Transient postoperative vascular endothelial growth factor(VEGF)-neutralisation improves graft survival in corneas with partly regressed inflammatory neovascularisation显示文摘 | Bachmann BO Luetjen-Drecoll E Bock F | 2009 | Br J Ophthalmol2009，93，8： | 1 |
| 5 | Thepot entialforwave disturbance in shallow Florida lakes显示文摘 | Bachmann R W Hoyer M V Canfield D E | | 0，，04： | 1 |
| 6 | Design,Implementation,and Experimental Results of a Quaternion-Based Kalman Filter for Human Body Motion Tracking显示文摘 | Yun X Bachmann E R | 2006 | IEEE Transactions on Robotics2006，22，6： | 1 |
| 7 | Testing and evaluation of an integrated GPS/INS system for small AUV navigation显示文摘 | Healey A J etc | 1999 | IEEE Journal of Oceaning Engineering1999，，： | 1 |
| 8 | A simplified quaternion-based algorithm for orienta- tion estimation from earth gravity and magnetic field measurements 显示文摘 | YUN X P BACHMANN E R MCGHEE R B | 2008 | IEEE Transactions on Instrumentation and Measurement2008，57，3： | 1 |
| 9 | Time depence of the expression of ICAM-1 (CD54) in human skin wounds 显示文摘 | J Dreβler Bachmann L Muller E | 1997 | Int J Legal Med1997，110，： | 1 |
| 10 | Effects of corn oil addition to the diet on the energy metabolism of heart, liver and kidney of female rats显示文摘 | Bachmann E Wcber E | 1990 | Pharmacol Toxieol1990，67，1： | 1 |
| 11 | Molecular and functional analysis of the Epstein-Barr virus LMP1 oncogene promoter in lymphoproliferative diseases显示文摘 | Rothenberger S Bachmann E Knecht H | 1997 | Exp Hematol1997，25，13： | 1 |
| 12 | Testing and Evaluation of an Integrated GPS/INS System for Small AUV Navigation 显示文摘 | X Yun E R Bachmann R B McGhee | 1999 | Journal of Oceanic Engineering (S0364-9059)1999，24，3： | 1 |
| 13 | The volatile an-esthetic sevoflurane inhibits activation of neutrophil granulo-cytes during simulated extracorporeal circulation 显示文摘 | Schmid E Krajewski S Bachmann D | 2012 | Int Im-munopharmacol2012，14，2： | 1 |
| 14 | 显示文摘 | | 1951 | J Am Chem Soc1951，73，： | 1 |
| 15 | The use of P-element transposons to generate transgenic flies 显示文摘 | Bachmann AKnust E | 2008 | Methods Mol Biol2008，420，： | 1 |
| 16 | Systematic characterization of amplitude-integrated EEG signals for monitoring the preterm brain显示文摘 | Griesmaier E Enot DP Bachmann M | 2013 | Pediatr Res2013，73，2： | 1 |
| 17 | Multiple-close pharmacokinetics of intravenously administeredcefoperazone and sulbactam when given in combination toinfected, seriously ill, elderly patients 显示文摘 | SCHWARTZ J I JAUREGUI L E BACHMANN K A | 1988 | Antimicrob AgentsChemother1988，32，5： | 1 |
| 18 | HPV vaccination with Gardasil: a breakthrough in women's health显示文摘 | Hanna E Bachmann G | 2006 | Expert Opin Biol Ther2006，6，11： | 1 |
| 19 | A simplified quater- nion-based algorithm for orientation estimation from earth gravity and magnetic field measurements 显示文摘 | Yun X Bachmann E R McGhee R B | 2008 | IEEE Transac- tions on Instrumentation and Measurement2008，57，3： | 1 |
| 20 | Design,implementation,and experimental results of a quaternion-based Kalman filter for human body motion tracking显示文摘 | Yun X P Bachmann E | 2006 | IEEE Transactions on Robotics2006，22，6： | 1 |
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