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| 1 | Parenting preschoolers with autism: Socioeconomic influences on wellbeing and sense of competence显示文摘BACKGROUND Previous research suggests that parents raising a child with autism experience higher levels of psychological distress than parents of typically developing children and parents of children with other developmental disorders. Little is known, however, about the intersection between the effects of socioeconomic status(SES) on the wellbeing and sense of parental competency of parents of preschoolers with autism and how it relates to child symptom severity.AIM To examine the relationship between their child's symptom severity, SES, as measured by neighbourhood advantage and occupational status, on the psychological wellbeing and perceived parenting competence among parents of preschoolers with autism.METHODS Parents of 117 preschool-aged children with a diagnosis of autism spectrum disorder(ASD), 107 mothers and 54 fathers, completed questionnaires about their child's symptoms of ASD and functioning, their own perceptions of their wellbeing and parental competence on entry to an early intervention program in Sydney, Australia. Parents also provided demographic information pertaining to their occupation, level of education attained and address(postcode). All children were also assessed for their severity of symptoms using the Autism Diagnostic Observation Schedule. The Australian Socioeconomic Index of occupationalstatus as a measure of familial SES and the Index of Relative Socio-economic Advantage and Disadvantage as a measure of neighbourhood advantage were used to examine the impact of SES on parental sense of competence and wellbeing.RESULTS Compared to normative populations, both mothers and fathers in our sample reported significantly higher levels of parenting sense of efficacy but lower levels of interest in the parenting role. Mothers also displayed higher levels of satisfaction. Both mothers and fathers displayed higher levels of depression than normative populations with mothers also reporting greater levels of stress and anxiety. Child symptom severity was associated with maternal parenting competency with these relationships amplified among mothers with higher familial SES and who lived in areas of greater neighbourhood advantage.Increased adaptive functioning was associated with better maternal wellbeing,particularly among mothers who lived in areas of greater neighbourhood advantage. Contrastingly, paternal parenting competence was generally not influenced by child adaptive functioning or symptom severity, although for those in higher familial SES brackets, children's symptom severity and maladaptive symptoms were negatively related to paternal sense of parenting efficacy. There was a trend towards moderate relationships between lower familial SES and greater depression, stress and anxiety among fathers, but no relationship with their child's ASD symptom severity or functioning.CONCLUSION SES differentially impacts wellbeing and sense of parenting competence and its relationship to the impact of child symptoms for mothers and fathers of preschoolers with autism. | Nisha E Mathew Karen L O Burton Anne Schierbeek Rudi ?rn?ec Amelia Walter Valsamma Eapen | 2019 | World Journal of Psychiatry2019，9，2： | 6 |
| 2 | Long-term irritable bowel syndrome symptom control with reintroduction of selected FODMAPs显示文摘AIM To investigate the long-term effect of dietary education on a low fermentable oligosaccharide, disaccharide and polyol(FODMAP) diet on irritable bowel syndrome(IBS) symptoms and quality of life(Qo L).METHODS Participants with IBS(Rome III) were randomized to two groups. Group I commenced a low FODMAP diet at baseline. At three months, group II, so far a comparator group, crossed over to a low FODMAP diet while group I started re-challenging foods. All patients completed the IBS SSS(IBS symptom severity scoring system, 0-500 points increasing with severity), IBS Qo L questionnaire(0-100 increasing with Qo L), a FODMAP specific food frequency questionnaire and provided a stool sample at baseline, three and six months for microbiome analysis.RESULTS Fifty participants were enrolled into group I(n = 23) or group II(n = 27). Participants in both groups were similar in baseline values but with more men in group I. There was a significantly lower IBS SSS(275.6 ± 63.6 to 128.8 ± 82.5 vs 246.8 ± 71.1 to 203.6 ± 70.1)(P < 0.0002) and increased Qo L(68.5 ± 18.0 to 83 ± 13.4 vs 72.9 ± 12.8 to 73.3 ± 14.4)(P < 0.0001) in group I vs group II at 3 mo. The reduced IBS SSS was sustained at 6 mo in group I(160 ± 102) and replicated in group II(124 ± 76). Fiber intake decreased on the low FODMAP diet(33 ± 17 g/d to 21 ± 8 g/d)(P < 0.01) and after re-introducing FODMAP containing foods increased again to 27 ± 9 g/d. There was no change seen in the intestinal microbiome when participants adopted a low FODMAP diet.CONCLUSION This study demonstrated that a reduction in FODMAPs improves symptoms in IBS and this improvement can be maintained while reintroducing FODMAPs. | Ruth M Harvie Alexandra W Chisholm Jordan E Bisanz Jeremy P Burton Peter Herbison Kim Schultz Michael Schultz | 2017 | World Journal of Gastroenterology2017，23，25： | 5 |
| 3 | Thiopurines and inflammatory bowel disease: Current evidence and a historical perspective显示文摘The use of thiopurines in inflammatory bowel disease(IBD) has been examined in numerous prospective, controlled trials, with a majority demonstrating a clinical benefit. We conducted this review to describe the historical and current evidence in the use of thiopurines in IBD. A systematic search was performed on MEDLINE between 1965 and 2016 to identify studies on thiopurines in IBD. The most robust evidence for thiopurines in IBD includes induction of remission in combination with anti-tumor necrosis factor(antiTNF) agents, and maintenance of remission and postoperative maintenance in Crohn's disease. Less evidence exists for thiopurine monotherapy in induction of remission, maintenance of ulcerative colitis, chemoprevention of colorectal cancer, and in preventing immunogenicity to anti-TNF. Evidence was often limited by trial design. Overall, thiopurines have demonstrated efficacy in a broad range of presentations of IBD. With more efficacious novel therapeutic agents, the positioning of thiopurines in the management of IBD will change and future studies will analyze the benefit of thiopurines alone and in conjunction with these new medications. | Jordan E Axelrad Abhik Roy Garrett Lawlor Burton Korelitz Simon Lichtiger | 2016 | World Journal of Gastroenterology2016，22，46： | 3 |
| 4 | 2008 estimate of worldwide rotavirus-associated mortality in children younger than 5 years before the introduction of universal rotavirus vaccination programmes: a systematic review and meta-analysis显示文摘 | Jacqueline E Tate Anthony H Burton Cynthia Boschi-Pinto A Duncan Steele Jazmin Duque Umesh D Parashar | 2012 | The Lancet Infectious Diseases2012，，2： | 2 |
| 5 | Placental oxidative stress:from miscrriage to pre-eclampsia显示文摘 | Burton GJ Jauniaux E | 2004 | J Soc Gynecol Investig2004，11，6： | 1 |
| 6 | Genetic base of 651Chinese soybean eultivars released during 1923 to 1995 显示文摘 | Cui Z L Thomas E Carter J Burton J W | 2000 | Crop Science2000，40，： | 1 |
| 7 | Prucalopride accelerates gastrointestinal and colonic transit in patients with constipation without a rectal evacuation disorder 显示文摘 | Bourns E Camilleri M Burton D | 2001 | Gastroenterology2001，120，2： | 1 |
| 8 | Effects of polyacrylamide application method on soil erosion and water infiltration显示文摘 | Burton D G Trenkel J E Shock C C | | 0，，： | 1 |
| 9 | Profile nitrous - oxide and carbon diox- ide concentrations in a soil subject to freezing显示文摘 | Burton D L Beauchamp E G | 1994 | Soil Science Socie- ty of America Journal1994，58，1： | 1 |
| 10 | Distribution of tobacco constituents in tobacco leaf tissue tobacco-special nitrosamines,nitrate,nitrite,and alkaloids显示文摘 | Burton H R Dye N K Bush L E | 1992 | Journal of Agricultural and Food Chemistry1992，40，6： | 1 |
| 11 | Contrast sensitivity after implantation of diffractive bifocal and monofocal intraocular lenses显示文摘 | Allen ED Burton RL | 1998 | J Cataract Refract Surg1998，24，： | 1 |
| 12 | A sustainable solution for dietary iron deficiency through plant biotechnology and breeding to increase seed ferritin control显示文摘 | Theil E C Burton J W Beard J L | 1997 | European Journal of Clinical Nutrition1997，51，4： | 1 |
| 13 | Genetic base for noah American public soybean cultivars released between 1947-1988显示文摘 | Gizlice Z Carter Jr T E Burton J W | 1994 | Crop Science1994，34，： | 1 |
| 14 | Oxidative stress显示文摘 | Burton GJ Jauniaux E | 2011 | Best Pract Res Clin Obstet Gynaecol2011，25，3： | 1 |
| 15 | The compact cities : just or just compact A preliminary analysis显示文摘 | Burton E | 2000 | Urban Studies2000，37，11： | 1 |
| 16 | Turnover of human tubular cells exposed to proteins in vivo and in vitro显示文摘 | Burton CJ Harper SJ Bailey E | 2001 | Kidney Int2001，59，2： | 1 |
| 17 | 显示文摘 | Burton B P Cockayne E | 1999 | Physical Review B1999，60，12： | 1 |
| 18 | The procell death bcl-2 family member,BNIP3,is localized to the nucleus of human glialcells:implications for glioblastoma multiforme tumor cells urvival under hypoxia显示文摘 | HENSON E S BAIJAL P | 2006 | Int J Cancer2006，118，7： | 1 |
| 19 | The compact city: just or just compact? a preliminary analysis显示文摘 | BURTON E | 2000 | Ur- ban Study2000，37，11： | 1 |
| 20 | Physical Activity Levels of Older Adults Receiving a Home Care Service显示文摘 | BURTON E LEWIN G BOLDY D | 2013 | Journal of Aging and Physical Activity2013，21，2： | 1 |
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