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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 2 | 与久坐者相比,职业运动员的肠道菌群在代谢组分,尤其是功能代谢水平上有所不同显示文摘目的有证据表明肠道菌群以及影响其结构和活性的因素在人类代谢、免疫和发育过程中发挥作用。我们曾报道,与久坐者相比,诸如职业运动员,配有相应饮食的极度体育活动者肠道菌群种属和代谢组分发生了改变。这次我们重点研究这些因素对菌群功能/代谢活动的影响,以进一步揭示运动者和久坐者间的差别。方法对专业国际橄榄球联盟球员(样本数为40例)和对照(样本数为46例)的肠道菌群进行代谢表型和功能宏基因组分析,并将结果与生活方式指标(比如饮食习惯)和临床评估指标(比如血清肌酸激酶)进行关联。结果与对照相比,运动员组中与肌肉更新和整体健康相关的信号通路(比如:氨基酸、抗生素生物合成和碳水化合物代谢)和肠道菌群代谢产物(比如:短链脂肪酸乙酸酯、丙酸酯和丁酸酯)有所增加。结论运动和久坐相比,其肠道菌群在宏基因组和代谢组学上比组织水平显示出更大差异,拓展了饮食.运动.肠道微生态模式新视野。 | Barton W Penney NC Cronin O Garcia-Perez I Molloy MG Holmes E Shanahan F Cotter PD O'Sullivan O 毛玲娜 宋震亚 | 2017 | 英国医学杂志中文版2017，20，7： | 2 |
| 3 | Fate of metals in waste combustion systems 显示文摘 | Barton R G Clark W D Seeker W R | 1990 | Combustion Science and Technology1990，74，： | 1 |
| 4 | 显示文摘 | Bahri P A Bandani J A Barton G W | 1995 | Computers and Chemical Engineering1995，，： | 1 |
| 5 | Receptor-mediated gene delivery to human peripheral blood mononuclear cells using anti-CD3 antibody coupled to polyethylenimine显示文摘 | O'NEIL M M KENNEDY C A BARTON R W | 2001 | Gene Therapy2001，，8： | 1 |
| 6 | Suggested methods for the quantitative descrip- tion of discontinuities in rock masses 显示文摘 | Barton W E | 1978 | Int J Rock Mech Min Sci & Geomech Abstr1978，15，6： | 1 |
| 7 | Transmission line resistance compression networks and applications to wireless power transfer显示文摘 | BARTON T W GORDONSON J M PERREAULT D J | 2015 | IEEE Journal of Emerging and Selected Topics in Power Electronics2015，3，1： | 1 |
| 8 | Enzyme therapy in type I Gaucher disease : comparative efficacy of mannose-terminated , glucocerebrosidase from natural and recombinant sources 显示文摘 | GRABOWSKI G A BARTON N W PASTORES G | 1995 | Ann Intern Med1995，122，1： | 1 |
| 9 | Dynamic optimization with state variable path constraints显示文摘 | Feehery W Barton P | 1998 | Computers and Chemical Engineering1998，22，4： | 1 |
| 10 | Reaction of some grasses to artificial salinization显示文摘 | Gausman H W Cowley W R Barton S H | 1954 | Agronomy Journal1954，46，41： | 1 |
| 11 | Comparison of ex- perimental and modelling studies for the microwave drying of ironbark timber显示文摘 | Lehne M Barton G W Langrish T A G | 1999 | Drying Technology1999，17，10： | 1 |
| 12 | MicroRNA control of PHABULOSA in leaf development:importance of pairing to the mieroRNA 5' region 显示文摘 | Mallory A C Reinhart B J Jones-Rhoades M W Tang G L Zamore P D Barton M K Barrel D P | 2004 | The EMBO Journal2004，23，： | 1 |
| 13 | Relative virulence of isolates of Sclerotinia homoeocarpa with varying sensitivity to propiconazole显示文摘 | Hsiang T Yang L Barton W | 1998 | European Journal of Plant Pathology1998，104，： | 1 |
| 14 | Nucleotide-metabolizing enzymes and lymphocyte differentiation 显示文摘 | Barton R W Goldschneider I | 1979 | Mol cell biochem1979，28，13： | 1 |
| 15 | Utility of the Arabidopsis FAE1 and yeast SLC1 - 1 genes for improve- ments in erucic acid and oil content in rapeseed 显示文摘 | Katavic V Friesen W Barton D L | 2000 | Biochem Soc Trans2000，28，6： | 1 |
| 16 | The concept of a mobile or molecular phase within the macromolecuiar network of coals : A debate 显示文摘 | Given P H Marzec A Barton W A | 1986 | Fuel1986，65，： | 1 |
| 17 | Further studies on the activation of the C-H bond in saturated hydrocarbons显示文摘 | BARTON D H R HAY- MOTHERWELL R S MOTHERWELL W B | 1983 | Tetrahedron Letter1983，24，19： | 1 |
| 18 | Accelerated corrosion and embrittlement of high-strength bridge wire显示文摘 | Barton S C Vermaas G W Duby P F | 2000 | Materials in Civil Engineering2000，12，1： | 1 |
| 19 | The future of electrocoagulation as a localized water treatment technology显示文摘 | HOLT P K BARTON G W MITCHELL C A | 2005 | Chemosphere2005，59，： | 1 |
| 20 | Baseline sensitivity and cross-resistance to demethylation-inhibiting fungicides in Ontario isolates of Sclerotinia homoeocarpa 显示文摘 | HSIANG T YANG L BARTON W | 1997 | Eur J Plant Pathol1997，103，： | 1 |
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