|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 食管黏膜下鳞状细胞癌及腺癌的高淋巴结转移率显示文摘Background and study aims: The application of endoscopic mucosectomy in early esophageal cancer is limited by the presence of lymph-node metastasis. The aim of this prospective study was to analyze the rate of lymph-node involvement relative to the depth of mucosal or submucosal tumor penetration, comparing squamous-cell carcinomas and adenocarcinomas. Patients and methods: A total of 60 patients with pT1 esophageal cancer- 24 with squamous-cell carcinomas (SCCs) and 36 with adenocarcinomas- were treated with transthoracic enbloc esophagectomy with two-field lymphadenectomy (n = 50) or transhiatal esophageal resection (n = 10). An average of 30 lymph nodes were examined, and the following characteristics were evaluated: histology, mucosal infiltration, depth of submucosal wall infiltration in three thirds (sm1, sm2, sm3), grading, resection category, ratio of metastatic to resected lymph nodes, and locations of metastatic nodes. Results: The rates of lymph-node metastasis were 0% for the 16 mucosal carcinomas and 45% for the 44 submucosal carcinomas (P< 0.01). There were no significant differences in the extent of lymph-node involvement between submucosal adenocarcinomas (41% ) and submucosal SCCs (50% ). Sm1 carcinomas were associated with a lower rate of lymph-node metastasis (SCCs 33% , adenocarcinomas 22% ) than sm3 carcinomas (SCCs 69% , adenocarcinomas 78% ). Two patients (9% ) with submucosal SCCs and five patients (23% ) with submucosal adenocarcinomas were classified as having stage pM1 lymph. The average lymph-node ratio in patients with pN1 was 0.13 for adenocarcinomas and 0.1 for SCCs (difference not significant). In the multivariate analysis, the parameters mucosal vs. submucosal (P < 0.01) and G1/G2 vs. G3 (P < 0.05) showed a significant impact in relation to metastatic lymph nodes. Conclusions: The most important factor for predicting lymph-node metastasis in early esophageal cancer is the presence of submucosal infiltration. Early adenocarcinomas and SCCs do not differ with regard to their rate of lymphatic involvement. The rate of lymph-node metastasis increases with the depth of submucosal infiltration, but metastases can already occur in sm1 lesions. Submucosal infiltration is a contraindication for endoscopic mucosectomy. Limited surgical procedures without adequate lymphadenectomy do not appear to be appropriate in the treatment of patients with submucosal esophageal carcinomas. | Bollschweiler E. Baldus S.E. Schrder W. A.H. Hlscher 张红凯 | 2006 | 世界核心医学期刊文摘(胃肠病学分册)2006，2，8： | 2 |
| 2 | Human-centrie connectivity enabled by body-coupled communications 显示文摘 | Baldus H Corroy S Fazzi A | 2009 | IEEE Commun Mag2009，47，6： | 1 |
| 3 | Splenectomy in proxi mal gastric cancer:frequency of lymph node metastasis to the splenic hilus显示文摘 | Monig S P Collet P H Baldus S E | 2001 | J Surg Oncol2001，76，2： | 1 |
| 4 | The simulation method of the galvanic coupling intrabody communication with different signal transmission paths 显示文摘 | Yong S Baldus H Espina J | 2011 | Instrumentation and Measurement IEEE Transactions on2011，60，23： | 1 |
| 5 | Plug'n play simplicity for wire- less medical body sensors显示文摘 | Falck T Baldus H Espina J | 2007 | Mobile Networks and Applications2007，12，23： | 1 |
| 6 | Reliable set - up of medical body - sensor networks 显示文摘 | BALDUS H KLABUNDE K MUESCH G | 2004 | Wireless Sensor Net- works In Wireless Sensor Networks2004，25，12： | 1 |
| 7 | High cyelooxygenase-2 expression following neoadjuvant radioehemotherapy is associated with minor histopathologic response and poor prognosis in esophageal cancer显示文摘 | Xi H Baldus SE Warnecke-Eberz U | 2005 | Clin Cancer Res2005，11，： | 1 |
| 8 | Combined laparo- scopic/endoscopic treatment of gastric stroma tumors 显示文摘 | Schiifer H Schneider PM Baldus SE | 2006 | Zen- tralbl Chit2006，131，3： | 1 |
| 9 | Cotrel Dubousset instrumentation for adolescent idiopathic scoliosis显示文摘 | Lenke L G Briwell K H Baldus C | 1992 | J Bone Joint Surg (Am)1992，74，154： | 1 |
| 10 | Lymph node staging of esophageal squamous cell carcinoma in patients with and without neoadjuvant radiochemotherapy: Histomorphologic analysis显示文摘 | Wolfgang Schr?der M.D. Stephan E. Baldus M.D. Stefan P. M?nig M.D. Tobias K. E. Beckurts M.D. Hans P. Dienes M.D. Arnulf H. H?lscher M.D | 2002 | World Journal of Surgery2002，，5： | 1 |
| 11 | Novel High-Performance Ceramics-Amorphous Inorganic Networks from Molecular Precursors显示文摘 | Baldus H Jansen M | | 0，，： | 1 |
| 12 | Neoadjuvant chemoradiotherapy for esophageal cancer:Impact on extracapsular lymph node involvement显示文摘AIM:To assess the effects of neoadjuvant chemoradiotherapy(CRT) on the presence of extracapsular lymph node involvement(LNI) and its prognostic value in patients with resected esophageal cancer.METHODS:Two hundred and ninety-eight patients with advanced esophageal cancer underwent esophagectomy between 1997 and 2006.One hundred and ninety patients(63.8%) were treated with neoadjuvant CRT prior to resection.A total of 986 metastatic LNs were examined.Survival of the patients was analyzed according to intra-and extra-capsular LNI.RESULTS:Five-year survival rate was 22.5% for the entire patient population.Patients with extracapsular LNI had a 5-year survival rate of 16.7%,which was comparable to the 15.8% in patients with infiltrated nodes of the celiac trunk(pM1lymph).In contrast to patients treated with surgery alone,neoadjuvant therapy resulted in signif icantly(P = 0.001) more patients with pN0/M0(51.6% vs 25.0%).In 17.6% of the patients with surgery alone vs 16.8% with neoadjuvant CRT,extracapsular LNI was detected.Neoadjuvant therapy does not reduce the occurrence of extracapsular LNI.CONCLUSION:Extracapsular LNI is an independent negative prognostic factor not influenced by neoadjuvant CRT.In a revised staging system for esophageal cancer,extracapsular LNI should be considered. | Ralf Metzger Elfriede Bollschweiler Uta Drebber Stefan P Mnig Wolfgang Schrder Hakan Alakus Martin Kocher Stephan E Baldus Arnulf H Hlscher | 2010 | World Journal of Gastroenterology2010，16，16： | 1 |
| 13 | The overexpression of c-met as a prognostic indicator for gastric carcinomacompared to p53 and p21 nuclear accumulation显示文摘 | Uta Drebber Stephan Baldus Britt Nolden Guido Grass Elfriede Bollschweiler Hans Dienes Arnulf H?lscher Stefan M?nig | 2008 | Oncology Reports2008，，6： | 1 |
| 14 | Frequency of nodal metastases to the upper mediastinum in Barrett’s cancer显示文摘 | W. Schr?der MD S. P. M?nig MD S. E. Baldus MD C. Gutschow MD P. M. Schneider MD A. H. H?lscher MD | 2002 | Annals of Surgical Oncology2002，，8： | 1 |
| 15 | High cyclooxygenase-2 expression following neoadjuvant radiochemotherapy is asso-ciated with minor histopathologic response and poor prognosis in esophageal cancer 显示文摘 | Xi H Baldus SE Wamecke-Eberz U | 2005 | Clin Cancer Res2005，11，23： | 1 |
| 16 | Ceramic fibers for matrix composites in high-temperature engine applications显示文摘 | BALDUS H P JANSEN M SPORN D | 1999 | Science1999，285，： | 1 |
| 17 | Transapical transcatheter aortic valve implantation using the JenaValveTM system: acute and 30-day results of the muhicentre CE-mark study显示文摘 | Treede H Mohr FW Baldus S | 2012 | Eur J Cardiothorac Surg2012，41，6： | 1 |
| 18 | Frequency of nodal metastases to the upper mediastinum in Barrett’s cancer显示文摘 | W. Schr?der MD S. P. M?nig MD S. E. Baldus MD C. Gutschow MD P. M. Schneider MD A. H. H?lscher MD | 2002 | Annals of Surgical Oncology2002，，8： | 1 |
| 19 | Novel high-performance ceramics--amorphous inorganic networks from molecular precursors 显示文摘 | BALDUS H P JANSEN M | 1997 | Angew Chem Int Ed Enigl1997，36，： | 1 |
| 20 | Ceramic fiber for matrix composites in high-temperature engine applications显示文摘 | Baldus H P Jansen M Sporn D | | 0，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员