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| 1 | Distribution and ecological risk assessment of some heavy metals in coastal surface sediments along the Red Sea,Egypt显示文摘The ecological risk assessment for Al,Zn,Cu,Ni,V,Pb,Cd,and Hg in surface sediment collected from the Egyptian Red Sea coast was evaluated using the Geo-accumulation Index(I_(geo)).Sediment Enrichment Factor(SEF) and Potential Ecological Risk Index(PERI) methods.The predominant heavy metal,aluminum,showed high concentrations along both of Aqaba Gulf(4378.8 ± 2554.1 μg/g) and southern part of the Red Sea(2972.8 + 1527.5 μg/g).while it recorded the lowest concentration in Suez Gulf(829.7 ± 398.2 μg/g).The determined heavy metal concentrations had the order of Al > Zn >-Ni > V > Pb > Cu > Cd > Hg.The statistical analyses showed some correlations among the heavy metals contents.Several international sediment quality guidelines were used to estimate the quality of the collected sediments.Interestingly,the recorded average heavy metals concentrations were lower than those of the permissible contents for sediment quality guidelines.The Geo-accumulation index calculations(I_(geo)) proved that the investigated region could be classified as an unpolluted area.Sediment Enrichment Factor(K_(SEF)) study showed high values in Suez Gulf region.The single pollution index analysis of heavy metals in the sediments(C^i_f) indicated that Al,Zn,V,and Pb were of natural origin,while Ni,Cd and Hg were seriously affected by human activities.Interestingly,amongst,all the determined heavy metals,Cd and Hg gave moderate ecological risk indicators. | Ahmed El Nemr Ghada F.El-Said Azza Khaled Safaa Ragab | 2016 | International Journal of Sediment Research2016，31，2： | 10 |
| 2 | Safety and efficacy of photodynamic therapy using BCECF-AM compared to mitomycin C in controlling post-operative fibrosis in a rabbit model of subscleral trabeculectomy显示文摘AIM:To evaluate the safety and efficacy of cellular photoablation using BCECF-AM[2',7'-bis-(2-carboxyethyl)-5-(and-6)-carboxyfluorescein,acetoxymethyl ester mixed isomers]as a method to control postoperative fibrosis in subscleral trabeculectomy(SST) compared to mitomycin C(MMC) in a rabbit model.· METHODS:A comparative prospective case-control animal study was conducted.Fourteen rabbits were subjected to SST with intraoperative use of wound modulating agents(MMC or BCECF-AM) of the right eye(study groups Ⅰ and Ⅱ respectively) and SST without use of intraoperative wound modulating agents for the left eye(control group Ⅱ).Two rabbits 4 eyes were considered as control group Ⅰ with no surgical intervention.BCECF-AM was injected subconjunctivally30 min before surgery followed by intraoperative illumination with diffuse blue light for 10 min.Antifibrotic efficacy was established by clinical response and histological examination.Clinical response was assessed by measuring intraocular pressure(IOP) at day 1,3,5,7,14,21 postoperatively.Success was defined by >20.0%reduction in IOP from the preoperative values without anti-glaucoma medications.· RESULTS:The mean percentage of reduction was35.0%in the study group Ⅰ with only one eye(14.3%) had12.5%reduction.The mean percentage of reduction was28.0%in the study group Ⅱ with two eyes(28.6%) in study group Ⅱ had 14.2%reduction each.Regarding the control group Ⅱ,the mean percentage of reduction was14.3%with 64.3%eyes had <20.0%reduction.There was a highly statistically significant difference between each of the study groups(right eyes) and the corresponding control group Ⅱ(left eyes) as regards the mean postoperative IOP values started from day 5 in both study groups and this highly significant difference remained so till the end of the follow up period.Histologically,MMC treated blebs showed thinning of conjunctival epithelium with marked reduction of the goblet cells relative to control.Marked sub-epithelial edema was seen along with variable collagen dispersion.Mild cellularity was noted in sub-epithelial tissue.BCECF-AM treated blebs showed normal conjunctival epithelial thickness with abundant goblet cells.Mild subepithelial edema was noted along with moderate collagen dispersion.No histological abnormality was noted in the ciliary body or the cornea in any of the studied groups.· CONCLUSION:Cellular photoablation using BCECF-AM is a safe and effective wound modulating agent to control postoperative fibrosis in trabeculectomy.However MMC considered as a more potent adjuvant to trabeculectomy than BCECF-AM in promoting IOP reduction. | Azza Mohamed Ahmed Said Rania Gamal Eldin Zaki Thanaa Helmy Mohamed Manal Ibraheem Salman | 2016 | International Journal of Ophthalmology(English edition)2016，9，3： | 5 |
| 3 | Corneal sensitivity,ocular surface health and tear film stability after punctal plug therapy of aqueous deficient dry eye显示文摘·AIM: To evaluate the effect of punctal occlusion using thermosensitive(smart plug) versus silicone plug for management of aqueous deficient dry eye on cornea sensitivity, ocular surface health and tear film stability.·METHODS: A comparative prospective interventiona case study included 45 patients with bilateral severe form of aqueous deficient dry eye. In each patient, the smar plug was inserted in the lower punctum of the right eye which was considered as study group 1 and silicone plug was inserted in the lower punctum of the left eye o the same patient which was considered as study group2. All patients were subjected to careful history taking and questionnaire for subjective assessment of severity of symptoms. Corneal sensitivity, corneal fluorescein rose bengal staining, Schirmer's I test, tear film break up time and conjunctival impression cytology were performed pre and 1, 3 and 6mo post plug insertion.·RESULTS: A statistically significant improvement in subjective and objective manifestations occurred following treatment with both types of plugs(P <0.01)The thermosensitive plug caused significant overal improvement, decrease in frequency of application o tear substitutes and improvement of conjunctiva impression cytology parameters in the inserted side(P <0.01). Canaliculitis was reported in two eyes(4.4% following punctal occlusion using thermosensitive plug(study group 1). Spontaneous plug loss occurred in 21eyes(46.6%) in the silicone plug group(study group 2).·CONCLUSION: Improvement of subjective and objective manifestations of aqueous deficient dry eye occurs following punctal plug occlusion. Thermosensitive plug has good patient's compliance with fewer complications and lower rates of loss compared to the silicone plug. | Azza Mohamed Ahmed Said Mona Elsayed Farag Tarek Mohamed Abdulla Othman Ali Othman Ziko Wesam Mohamed Osman | 2016 | International Journal of Ophthalmology(English edition)2016，9，11： | 4 |
| 4 | Differential expression of cell cycle regulators in HCV-infection and related hepatocellular carcinoma显示文摘AIM:To investigate cell cycle proteins in chronic hepatitis C virus infection in order to analyze their role in the process of hepatocyte transformation and to characterize their prognostic properties. METHODS:Subjects of the current study included 50 cases of chronic hepatitis C(CHC) without cirrhosis,30 cases of CHC with liver cirrhosis(LC) ,and 30 cases of hepatitis C-related hepatocellular carcinoma(HCC) admitted to the Department of Hepato-Gastroenterology,Theodor Bilharz Research Institute(TBRI) ,Giza,Egypt.Fifteen wedge liver biopsies,taken during laparoscopic cholecystectomy,were also included as normal controls.Laboratory investigations including urine and stool analysis,liver function tests and prothrombin concentration;serologic markers for viral hepatitis and ultrasonography were done for all cases of the study together with immunohistochemical analysis using primary antibodies against Cyclin D1,Cyclin E,p21,p27 and Rb/p105 proteins. RESULTS:Normal wedge liver biopsies didn't express Cyclin E or Rb/p105 immunostaining but show positive staining for Cyclin D1,p21 and p27.Cyclin D1 expressed nuclear staining that was sequentially increased from CHC to LC(P<0.01) to HCC(P<0.001) cases;meanwhile,Cyclin E revealed nuclear positivity only in the case of HCCs patients that was directly correlated to Rb/p105 immuno-reactivity.The expression of p21 and p27 was significantly increased in CHC and LC cases compared to normal controls and HCCs with no significant difference between well-and poorlydifferentiated tumors.p21 showed only a nuclear pattern of staining,while,p27 presented with either cytoplasmic and/or nuclear reactivity in all studied cases.Correlation analysis revealed a direct relation between Cyclin D1 and p21 in CHC cases(P<0.001) ,between Cyclin D1 and Cyclin E in HCCs(P<0.01);however,an inverserelationship was detected between Cyclin D1 and p21 or p27(P<0.001) and between p21 and Rb/p105(P<0.05) in HCCs. CONCLUSION:Upregulation of Cyclin D1 in CHC plays a vital role in the development and differentiation of HCC;while,Cyclin E may be a useful marker for monitoring tumor behavior.p21 and p27 can be used as predictive markers for HCC.Furthermore,higher expression of Rb/p105 as well as inverse relation with p21 and histologic grades suggests its important role in hepatic carcinogenesis. | Azza E El Bassiouny Mona M Nosseir Mona K Zoheiry Noha A Ameen Ahmed M Abdel-Hadi Ibrahim M Ibrahim Suher Zada Abdel-Hakeem Saad El-Deen Nora E El-Bassiouni | 2010 | World Journal of Hepatology2010，2，1： | 3 |
| 5 | Parameters Affecting Energy Consumption for Producing High Carbon Ferromanganese in a Closed Submerged Arc Furnace显示文摘The power consumption is considered to be the most important factor affecting the production cost of ferromanganese alloy.Different parameters affecting the energy consumption for industrial production of high carbon ferromanganese HCFeMn were investigated in a closed submerged arc furnace.The analysis of industrial data revealed that the most energy-consumed factors were the direct reduction by solid carbon,Boudouard reaction,metal and slag formation,and decomposition of fluxing materials(limestone and dolomite).To reduce the energy consumption and minimize the energy losses in the production process of HCFeMn,it was recommended to use Mn blend with minimum Mn to Fe ratio of 6and lower SiO2content or higher basicity.The added coke must be adjusted according to the material balance to prevent the over-coke and to minimize the highly endothermic'Boudouard reaction'.In addition,it was recommended to work at basic slags with the ratio of(CaO+MgO)to SiO2equal to 1.0-1.2instead of much higher slag basicity.Furthermore,the mass losses had to be minimized through adjusting the handling and charging process and to take care of all metal produced. | Azza Ahmed Hossam Halfa Mohamed K.El-Fawakhry Hoda El-Faramawy Mamdouh Eissa | 2014 | Journal of Iron and Steel Research(International)2014，21，7： | 3 |
| 6 | Clinical benefits of biochemical markers of bone turnover in Egyptian children with chronic liver diseases显示文摘AIM: To investigate the association between serum insulin-like growth factor 1 (IGF-1), osteocalcin, and parathyroid hormone (PTH) levels with the etiology and clinical condition of patients with chronic liver disease.METHODS: Eighty children with hepatocellular damage were divided into 3 groups according to the etiology of disease infection: bilharziasis (9 patients), hepatitis B virus (HBV, 12 patients) and hepatitis C virus (HCV, 29 patients). The Child score index was found as A in 24 patients, B in 22 patients, C in 4 patients. Thirty healthy children served as control group. HBsAg, HBcAbIgM, HBcAbIgG, and anti-HCV were detected using ELISA technique. HCV-RNA was measured by reverse transcription polymerase chain reaction (RT-PCR). Anti-bilharzial antibodies were detected by indirect haem- agglutination test. Liver function tests were performed using autoanalyser. Serum IGF-1, osteocalcin and PTH levels were measured by ELISA technique. Abdominal ultrasonography was also conducted.RESULTS: Serum IGF-1 level was significantly lower in all patient groups with liver diseases, while serum osteocalcin and PTH levels were significantly elevated in patients with HBV and HCV infections compared with the control group. Serum osteocalcin and PTH concentrations were measured with the severity of liver disease from Child A to C. Child A patients unexpectedly showed significantly reduced IGF-1 levels in comparison to patients staged as Child B or C. Serum osteocalcin level was negatively correlated with albumin (14.7 ± 0.54 vs 3.6 ± 0.10, P < 0.05), while that for PTH was positivelycorrelated with total protein (70.1 ± 2.17 vs 6.7 ± 0.10, P < 0.05) in patients with HCV infection.CONCLUSION: Low serum IGF-1 level seems to play a critical role in the bone loss in patients with chronic liver disease. Elevated biochemical markers of bone remodeling suggest high-turnover in patients with viral infection and reflect severity of the clinical stage. | Karam A Mahdy Hanaa H Ahmed Fathia Mannaa Azza Abdel-Shaheed | 2007 | World Journal of Gastroenterology2007，13，5： | 3 |
| 7 | Removal of direct blue-86 from aqueous solution by new activated carbon developed from orange peel 显示文摘 | AHMED E1 Nemr OLA Abdelwahab AZZA Khaled | 2009 | Journal of Hazardous Materials2009，161，1： | 1 |
| 8 | Distribution and Statistical Analysis of Leachable and Total Heavy Metals in the Sediments of the Suez Gulf显示文摘 | Ahmed El Nemr Azza Khaled Amany El Sikaily | 2006 | Environmental Monitoring and Assessment (-)2006，，1： | 1 |
| 9 | Comprehensive risk assessment of heavy metals in surface sediments along the Egyp- tian Red Sea coast显示文摘 | Dalia M S A S Azza K Ahmed E N | 2014 | The Egyptian Journal of Aquatic Research2014，40，4： | 1 |
| 10 | Removal of Direct N Blue-106 from artificial textile dye effluent using activated carbon from orange peel: Adsorption isotherm and kinetic studies显示文摘 | Azza Khaled Ahmed El Nemr Amany El-Sikaily Ola Abdelwahab | 2008 | Journal of Hazardous Materials2008，，1： | 1 |
| 11 | Polychlorinated biphenyls and chlorinated pestiddes in mussels from the Egyptian Red Sea coast显示文摘 | AZZA K AHMED E N TAREK O S | | 0，，： | 1 |
| 12 | Prevalence of Candida colonization in preterm newborns and VLBW in neonatal intensive care unit: role of maternal colonization as a risk factor in transmission of disease显示文摘 | Gihan Yousef Ali Eglal Hussein S. S. Algohary Khalid Ahmed Rashed Mohammed Almoghanum Azza AbdelRahman Khalifa | 2012 | Journal of Maternal-Fetal and Neonatal Medicine2012，，6： | 1 |
| 13 | Polychlorinated biphenyls and chlorinated pesticides in mussels from the Egyptian Red Sea coast显示文摘 | Azza K Ahmed E N Tarek O S | 2004 | Chemosphere2004，54，： | 1 |
| 14 | Polychlorinated biphenyls and chlorinated pesticides in mussels from the Egyptian Red Sea coast显示文摘 | Azza Khaled Ahmed El Nemr Tarek O. Said Amany El-Sikaily Aly M.A. Abd-Alla | 2003 | Chemosphere2003，，10： | 1 |
| 15 | Molecular and serological prevalence of Toxoplasma gondii in pregnant women and sheep in Egypt显示文摘Objective: To investigate molecular and serological prevalence of Toxoplasma gondii(T.gondii) in pregnant women and sheep in Egypt.Methods: Blood samples collected from healthy 364 pregnant women and 170 sheep were investigated for T.gondii antibodies and parasitemia using highly specific and sensitive surface antigen(TgSAG2) based enzyme linked immunosorbent assay(ELISA)and real time-polymerase chain reaction(RT-PCR).Results: Overall prevalence of T.gondii was 51.76%, 17.65% in sheep, 33.79%, 11.81%in pregnant women, using ELISA and RT-PCR respectively.Significant differences in T.gondii prevalence were observed on the basis of contact with cats or soil in pregnant women using either RT-PCR or ELISA.In pregnant women, a significant increase was detected in aged and those eating under-cooked mutton using simultaneous ELISA/RTPCR.Conclusions: Consumption of under-cooked infected mutton is an important source of human infection and the combination of the two assays provide accurate and precise data during infection. | Hany M.Ibrahim Azza H.Mohamed Ahmed A.El-Sharaawy Hend E.El-Shqanqery | 2017 | Asian Pacific Journal of Tropical Medicine2017，10，10： | 1 |
| 16 | Impact of biliary complications on quality of life in live-donor liver transplant recipients显示文摘BACKGROUND Despite significant advancements in liver transplantation(LT)surgical procedures and perioperative care,post-LT biliary complications(BCs)remain a significant source of morbidity,mortality,and graft failure.In addition,data are conflicting regarding the health-related quality of life(HRQoL)of LT recipients.Thus,the success of LT should be considered in terms of both the survival and recovery of HRQoL.AIM To assess the impact of BCs on the HRQoL of live-donor LT recipients(LDLT-Rs).METHODS We retrospectively analysed data for 25 LDLT-Rs who developed BCs post-LT between January 2011 and December 2016 at our institution.The Short Form 12 version 2(SF 12v2)health survey was used to assess their HRQoL.We also included 25 LDLT-Rs without any post-LT complications as a control group.RESULTS The scores for HRQoL of LDLT-Rs who developed BCs were significantly higher than the norm-based scores in the domains of physical functioning(P=0.003),role-physical(P<0.001),bodily pain(P=0.003),general health(P=0.004),social functioning(P=0.005),role-emotional(P<0.001),and mental health(P<0.001).No significant difference between the two groups regarding vitality was detected(P=1.000).The LDLT-Rs with BCs had significantly lower scores than LDLT-Rs without BCs in all HRQoL domains(P<0.001)and the mental(P<0.001)and physical(P=0.0002)component summary scores.CONCLUSION The development of BCs in LDLT-Rs causes a lower range of improvement in HRQoL. | Reginia Nabil Guirguis Ehab Hasan Nashaat Azza Emam Yassin Wesam Ahmed Ibrahim Shereen A Saleh Mohamed Bahaa Mahmoud El-Meteini Mohamed Fathy Hany Mansour Dabbous Iman Fawzy Montasser Manar Salah Ghada Abdelrahman Mohamed | 2021 | World Journal of Hepatology2021，13，10： | 1 |
| 17 | Polychlorinated biphenyls and chlorinated pesticides in mussels from the Egyptian Red Sea coast显示文摘 | AZZA K AHMED E N TAREK O S | 2004 | Chemosphere2004，4，： | 1 |
| 18 | Pharmacological preconditioning with nicorandil and pioglitazone attenuates myocardial ischemia/reperfusion injury in rats显示文摘 | Lamiaa A. Ahmed Hesham A. Salem Amina S. Attia Azza M. Agha | 2011 | European Journal of Pharmacology2011，，1： | 1 |
| 19 | Removal of toxic chromium from wastewater using green alga Ulva lactuca and its activated carbon显示文摘 | Amany El-Sikaily Ahmed El Nemr Azza Khaled Ola Abdelwehab | 2007 | Journal of Hazardous Materials2007，，1： | 1 |
| 20 | Removal of toxic chromium from wastewater using green alga Ulva lactuca and its activated carbon显示文摘 | Amany El-Sikaily Ahmed El Nemr Azza Khaled Ola Abdelwehab | 2007 | Journal of Hazardous Materials2007，，1： | 1 |
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