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| 1 | Intralesional steroid is beneficial in benign refractory esophageal strictures:A meta-analysis显示文摘AIM To analyze the effect of intralesional steroid injections in addition to endoscopic dilation of benign refractory esophageal strictures.METHODS A comprehensive search was performed in three databases from inception to 10 April 2017 to identify trials, comparing the efficacy of endoscopic dilation to dilation combined with intralesional steroid injections. Following the data extraction, meta-analytical calculations were performed on measures of outcome by the randomeffects method of Der Simonian and Laird. Heterogeneity of the studies was tested by Cochrane's Q and I^2 statistics. Risk of quality and bias was assessed by the Newcastle Ottawa Scale and JADAD assessment tools.RESULTS Eleven articles were identified suitable for analyses, involving 343 patients, 235 cases and 229 controls in total. Four studies used crossover design with 121 subjects enrolled. The periodic dilation index(PDI) was comparable in 4 studies, where the pooled result showed a significant improvement of PDI in the steroid group(MD:-1.12 dilation/month, 95% CI:-1.99 to -0.25 P = 0.012; I^2 = 74.4%). The total number of repeat dilations(TNRD) was comparable in 5 studies and showed a non-significant decrease(MD:-1.17, 95%CI:-0.24-0.05, P = 0.057; I^2 = 0), while the dysphagia score(DS) was comparable in 5 studies and did not improve(SMD: 0.35, 95%CI:-0.38, 1.08, P = 0.351; I^2 = 83.98%) after intralesional steroid injection.CONCLUSION Intralesional steroid injection increases the time between endoscopic dilations of benign refractory esophageal strictures. However, its potential role needs further research. | László Szapáry Benedek Tinusz Nelli Farkas Katalin Márta Lajos Szakó Agnes Meczker Roland Hágendorn Judit Bajor Aron Vincze Zoltan Gyongyi Alexandra Mikó Dezso Csupor Péter Hegyi Balint Eross | 2018 | World Journal of Gastroenterology2018，24，21： | 7 |
| 2 | Chronic kidney disease severely deteriorates the outcome of gastrointestinal bleeding: A meta-analysis显示文摘AIM To understand the influence of chronic kidney disease(CKD) on mortality, need for transfusion and rebleeding in gastrointestinal(GI) bleeding patients.METHODS A systematic search was conducted in three databases for studies on GI bleeding patients with CKD or endstage renal disease(ESRD) with data on outcomes of mortality, transfusion requirement, rebleeding rate and length of hospitalization(LOH). Calculations were performed with Comprehensive Meta-Analysis software using the random effects model. Heterogeneity was tested by using Cochrane's Q and I2 statistics. Mean difference(MD) and OR(odds ratio) were calculated.RESULTS1063 articles(EMBASE: 589; PubM ed: 459; Cochrane: 15) were found in total. 5 retrospective articles and 1 prospective study were available for analysis. These 6 articles contained data on 406035 patients, of whom 51315 had impaired renal function. The analysis showed a higher mortality in the CKD group(OR = 1.786, 95%CI: 1.689-1.888, P < 0.001) and the ESRD group(OR = 2.530, 95%CI: 1.386-4.616, P = 0.002), and a rebleeding rate(OR = 2.510, 95%CI: 1.521-4.144, P < 0.001) in patients with impaired renal function. CKD patients required more unit red blood cell transfusion(MD = 1.863, 95%CI: 0.812-2.915, P < 0.001) and spent more time in hospital(MD = 13.245, 95%CI: 6.886-19.623, P < 0.001) than the controls.CONCLUSION ESRD increases mortality, need for transfusion, rebleeding rate and LOH among GI bleeding patients. Prospective patient registries and observational clinical trials are crucially needed. | Roland Hágendorn Nelli Farkas Aron Vincze Zoltán Gyongyi Dezso Csupor Judit Bajor Bálint Eross Péter Csécsei Andrea Vasas Zsolt Szakács László Szapáry Péter Hegyi Alexandra Mikó | 2017 | World Journal of Gastroenterology2017，23，47： | 3 |
| 3 | Self-orgnized shortcuts in the argentine ant 显示文摘 | Goss S Aron S Deneubourg J L | 1989 | Naturwissenschaften1989，76，： | 1 |
| 4 | Deriving inherent optical properties from water color: a multiband quasi-analytical algorithm for optically deep waters显示文摘 | Lee Z P Carder K L Arone R A | 2002 | Applied Optics2002，41，27： | 1 |
| 5 | A model of market power and efficiency in private electronic exchanges 显示文摘 | Aron R Ungar L Valluri A | 2008 | European Journal of Operational Research2008，187，3： | 1 |
| 6 | The self-organizing exploratory pattern of the argentine ant显示文摘 | DENEUBOURG J L ARON S GOSS S | | 0，，02： | 1 |
| 7 | Measuring progress toward achieving hemoglobin Alc goals in diabetes care: pass/fail or partial credit显示文摘 | Pogach L Engelgau M Aron D | 2007 | JAMA2007，297，5： | 1 |
| 8 | Seasonal affective disorder and the G-protein beta-3-subunit C825T polymorphism 显示文摘 | Johansson C Willeit M Aron L | 2004 | Biol Psychiatry2004，55，3： | 1 |
| 9 | Understanding platelet dysfunction in sepsis 显示文摘 | Pigozzi L Aron JP Ball J | 2016 | Intensive Care Med2016，42，4： | 1 |
| 10 | Deriving inherent optical properties from water color: a multi-band quasi-analytical algorithm for optically deep waters 显示文摘 | LEE Z P CARDER K L ARONE R A | 2002 | Applied Optics2002，41，27： | 1 |
| 11 | Effects of Whole-Body Vibration Exercise on Lower-Extremity Muscle Strength and Power in an Older Population: A Randomized Clinical Trial显示文摘 | Rees Sven S Murphy Aron J Watsford Mark L | 2008 | Physical Therapy2008，，4： | 1 |
| 12 | Self-organized shortcuts in the argentine anti显示文摘 | Goss S Aron S Deneubourg J L | 1989 | Naturwissen Chaften1989，76，： | 1 |
| 13 | Depsipeptide (FR901228) induces histone acetylation and inhibition of histone deacetylase in chronic lymphocytic leukemia cells concurrent with activation of caspase 8 mediated apoptosis and down-regulation of c-FLIP protein显示文摘 | Aron J L Parthun M R Marcucci G | 2003 | Blood2003，102，2： | 1 |
| 14 | Self-organized shortcuts in the Argentine ant显示文摘 | SGoss S Aron J L Deneubourg J M Pasteels | 1989 | Naturwissenchafien1989，76，： | 1 |
| 15 | REST and stress resistance in aging and Alzheimer's disease显示文摘 | Lu T Aron L Zullo J | 2014 | Nature2014，507，7493： | 1 |
| 16 | Gone but not forgotten:the search for the lost surgical specimens:application of quality improvement techniques in reducing medical error显示文摘 | Slavin L Best MA Aron DC | 2001 | Qual Manag Health Care2001，10，： | 1 |
| 17 | Stanley: The robot that won the DARPA grand challenge 显示文摘 | THRUN S MONTEMERLO M DAHLKAMP H STAVENS D ARON A DIEBEL J FONG P GALE J HALPENNY M HOFFMANN G LAU K OAKLEY C PALATUCCI M PRATT V STANG P STROHBAND S DUPONT C JENDROSSEK L E KOELEN C MARKEY C RUMMEL C VAN N J JENSEN E ALESSANDRINI P BRADSKI G DAVIES B ETTINGER S KAEHLER A NEFIAN A MAHONEY P | 2006 | Journal of Field Robotics2006，23，9： | 1 |
| 18 | Seasonality and Period-Doubling Bifurcations in an Epidemic Model显示文摘 | Aron J L Schwartz I B | 1984 | J Theor Biol1984，110，： | 1 |
| 19 | Quality indicators for diabetes mellitus in the ambu- latory setting: using the Delphi method to inform performance mea- surement development显示文摘 | Aron D Pogach L | 2008 | Qual Saf Health Care2008，17，5： | 1 |
| 20 | Landsat-5 TM and land- sat-7 ETM + absolute radiometric calibration using the reflectance- based method 显示文摘 | Thome K J Helder D L Aron D | 2004 | IEEE Transactions on Geoscience and Remote Sensing2004，42，12： | 1 |
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