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| 1 | Exposure risk to carcinogenic PAHs in indoor-air during biomass combustion whilst cooking in rural India显示文摘 | Khanna R N Bhargava S K | 2004 | Atmospheric Environment2004,38,28: | 1 |
| 2 | A risk-based model for predicting the impact of using condoms on the spread of sexually transmitted infections显示文摘We create and analyze a mathematical model to understand the impact of condom-use and sexual behavior on the prevalence and spread of Sexually Transmitted Infections(STIs).STIs remain significant public health challenges globally with a high burden of some Sexually Transmitted Diseases(STDs)in both developed and undeveloped countries.Although condom-use is known to reduce the transmission of STIs,there are a few quantitative population-based studies on the protective role of condom-use in reducing the incidence of STIs.The number of concurrent partners is correlated with their risk of being infectious by an STI such as chlamydia,gonorrhea,or syphilis.We develop a Susceptible-Infectious-Susceptible(SIS)model that stratifies the population based on the number of concurrent partners.The model captures the multi-level heterogeneous mixing through a combination of biased(preferential)and random(proportional)mixing processes between individuals with distinct risk levels,and accounts for differences in condom-use in the low-and high-risk populations.We use sensitivity analysis to assess the relative impact of high-risk people using condom as a prophylactic intervention to reduce their chance of being infectious,or infecting others.The model predicts the STI prevalence as a function of the number of partners of an individual,and quantifies how this distribution of effective partners changes as a function of condom-use.Our results show that when the mixing is random,then increasing the condom-use in the high-risk population is more effective in reducing the prevalence than when many of the partners of high-risk people have high risk.The model quantifies how the risk of being infected increases for people who have more partners,and the need for high-risk people to consistently use condoms to reduce their risk of infection. | Asma Azizi Karen Ríos-Soto Anuj Mubayi James MHyman | 2017 | Infectious Disease Modelling2017,2,1: | 1 |
| 3 | Improved produetion of natural food preservative 8- poly- 1- lysine using a novel producer Bacillus cereus 显示文摘 | Anuj H Chheda Madhavi R Vernekar | 2014 | Food Bioscience2014,9,7: | 1 |
| 4 | Synthesis of mesoporous hexagonal titanium aluminosphate molecular sieves and their catalytic applieations显示文摘 | Kapoor M P Anuj R | 2000 | Applied Catalysis2000,203,: | 1 |
| 5 | Selective catalytic reduction of NO under ambient conditions using ammonia as reducing agent and MFI zeolites as catalysts 显示文摘 | Roberge D Anuj R Kaliaguine S | 1996 | Applied Catalysis B: Environmental1996,10,4: | 1 |
| 6 | Biomedical applications of colla- gen 显示文摘 | Chi H L Anuj S A Yugyung L R | 2002 | International Journal of Pharmaeeuties2002,221,12: | 1 |
| 7 | Large scale, highly conductive and patterned transparent films of silver nanowires on arbitrary substrates and their application in touch screens 显示文摘 | Anuj R Madaria Akshay Kumar and Chongwu Zhou | 2011 | Nanotechnology2011,22,24: | 1 |
| 8 | Sythesis of mesoporous hexagonal titanium aluminosphate molecular sieves and their catalytic applications显示文摘 | Anuj R | 2000 | Applied Catalysis2000,203,2: | 1 |
| 9 | IDH1 mutation is suffi- cient to establish the glioma hypermethylator phenotype 显示文摘 | Sevin T Daniel R Anuj G | 2012 | Nature2012,483,7390: | 1 |
| 10 | Transitioning patients with inflammatory bowel disease from hospital-based to rapid home-based infliximab: A stepwise, safety and patient-orientated process towards sustainability显示文摘BACKGROUND Infliximab and other intravenous biologic infusions are increasingly used for chronic disorders like inflammatory bowel disease(IBD).Rapid infliximab and home-based infusions are attractive solutions to address resource and capacity issues for infusion centres,yet infliximab infusion reactions reportedly occur in up to 25%of patients with IBD,even at the manufacturers’recommended infusion duration of 2 h.AIM To evaluate the safety,cost and patient satisfaction of transitioning from hospitalbased,standard 2 h to rapid home-based,30-min infliximab infusions.METHODS All patients receiving rapid infliximab infusions for IBD between 2014 to 2017(39 mo)were compared with those who received standard two-hour IFX infusions between 2005-2013(96 mo)at a single IBD centre.Data(per-infusion and perindividual)including adverse drug reactions(ADR),duration(based on needledeparture time)and other clinical data were extracted from electronic medical records.Multivariable logistical regression analysis assessed factors potentially associated with increased risk of ADRs to rapid infusions.The primary outcome was the safety[as per relative risk(RR)of (ADR)of(1)rapid 30 m infusions(both hospital-and home-based)vs standard 2 h infliximab infusions.Also,relative cost per infusion and patient satisfaction and productivity were evaluated in rapid infusion recipients who transitioned to home-based infusions.RESULTS Of 129 patients who received 1461 rapid IFX infusions(2014-2017)were compared with 169 patients who received 2214 standard IFX infusions(2005-2013).Within the rapid cohort,55(42.6%)were males,median age 42 years(range 18,86),114(84%)had Crohn’s disease(CD)with a median disease duration 5 years(0,36).Median needle to departure time was higher in the standard than the rapid protocol group,108(70,253)vs 50(33,90)min,(P<0.001),with a per infusion cost of$AUD 107.50 vs$49.77,respectively(both P<0.001).There was no difference in median infusion duration or costs between rapid home vs hospital-based infusions(P=0.21).8 patients in the rapid infliximab cohort had an ADR compared with 23 standard infliximab recipients(RR 0.55%vs 1.04%respectively),hence a higher likelihood of ADR with standard compared to rapid infusions[RR 3.0,95%CI(1.2,7.7),P=0.02].No ADRs were observed in 405 rapid home-based infusions.A lower body mass index(<22 kg/m2),presence of one or more extra intestinal manifestations,longer disease duration(>3 years)and previous exposure to another biologic were each independently associated with a higher likelihood of reaction(s)to rapid infusions.All(100%)survey respondents preferred the rapid vs standard infusions,however within rapid infusion recipients,61.3%found home based infusions more inconvenient than hospitalbased infusions despite a median of 0 h per week missed from paid work and no self-reported loss of work productivity.CONCLUSION Transitioning to rapid infliximab infusions appears very safe with significant cost benefit,patient satisfaction and avails the provision of safe,efficient,home-based infliximab infusions by IBD centres worldwide. | Anuj Bohra Qurat-Al-Ain Rizvi Charlotte Yuen Yu Keung Abhinav Vasudevan Daniel R van Langenberg | 2020 | World Journal of Gastroenterology2020,26,36: | 0 |