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148篇 您的检索式:作者名="Angelo L D"
    题名 作者 年代 出处 被引量
1一种miRNA标记在胶质瘤侵袭性表型的确定与预后评估中的价值(英文)显示文摘Gliomas represent a disparate group of tumours for which there are to date no cure. Thus,there is a recognized need for new diagnostic and therapeutic approaches based on increased understanding of their molecular nature. We performed the comparison of the microRNA( miRNA) profile of 8 WHO grade II gliomas and 24 higher grade tumours( 2 WHO grade III and 22 glioblastomas) by using the Affymetrix Gene Chip miRNA Array v. 1. 0. A relative quantification method( RT-q PCR) with standard curve was used to confirm the 22 miRNA signature resulted by array analysis. The prognostic performances of the confirmed miRNAs were estimated on the Tumor Cancer Genome Atlas( TCGA) datasets. We identified 22 miRNAs distinguishing grade II gliomas from higher grade tumours.RT-q PCR confirmed the differential expression in the two patients' groups for 13 out of the 22 miRNAs. The analysis of the Glioblastoma Multiforme( GBM) and Lower Grade Glioma( LGG) datasets from TCGA demonstrated the association with prognosis for 6 of those miRNAs. Moreover,in the GBM dataset miR-21 and miR-210 were predictors of worse prognosis in both univariable and multivariable Cox regression analyses( HR 1. 19,P = 0. 04,and HR 1. 18,P = 0. 029 respectively). Our results support a direct contribution of miRNAs to glioma cancerogenesis and suggest that miR-21 and miR-210 may play a role in the aggressive clinical behaviour of glioblastomas.Barbano R Palumbo O Pasculli B Galasso M Volinia S D'Angelo V Icolaro N Coco M Dimitri L Graziano P Copetti M Valori VM Maiello E Carella M Fazio VM Parrella P 2014中华神经外科疾病研究杂志2014,13,5:6
2Treatment of symptomatic intracranial arachnoid cysts by stereotactic cyst-ventricular shunting显示文摘 Gorgoglione L Catapano G 1999Stereotact Funct Neurosurg1999,72,1:1
3Nanophase in- termetallic FeAI obtained by sintering after mechanical alloying 显示文摘ANGELO L D ONOFRIO L D GONZALEZ G 2009Journal oi' Alloys and Compounds2009,483,12:1
4Teaching Neurolmage: spinalextradural arachnoid cyst: a rare cause of back pain显示文摘De BP Lucantoni C D'Angelo L 2008Neurology2008,71,9:1
5Effect of inner myometrium on reproductive outcome after IVF 显示文摘Gianaroli L Gordts S D' Angelo A 2005Reprod Biomed Online2005,10,:1
6Phase transformation study on NiTsA125 and Nis0A150 during mechanical alloying显示文摘Angelo L D Gonzalez G Ochoa J 2007Journal of Alloys and Compounds2007,,:1
7Marked decrease of serum Ca 125 levels after Denver shunt placement in a patient with cirrhosis and refractory ascites显示文摘Leggio L Abenavoli L D'Angelo C 2006Dig Dis Sci2006,51,9:1
8Involvement of peroxisome proliferator-activated receptorβ/δ(PPARβ/δ)in BDNF signaling during aging and in Alzheimer disease:possible role of 4-hydroxynonenal(4-HNE)显示文摘Benedetti E D'Angelo B Cristiano L 2014Cell Cycle2014,13,8:1
9Treatment of symptomatic intracranial arachnoid cysts by stereotatic cystventricular shunting显示文摘D'Angelo V Gorgoglione L Catapano G 1999Stereotact Funct Neurosurg1999,72,1:1
10Hydrogen production from glycerol on Ni/Al 2 O 3 cata-lyst显示文摘Sánchez Esteban A D’Angelo Miguel A Comelli Raúl A 2010International Journal of Hydrogen Energy2010,35,:1
11Evaluation of a new rapid quantitative D-dimer assay in patients with clinically suspected deep vein thrombosis显示文摘D'Angelo A D'Alessandro G Tomassini L 0,,3:1
12Surgical treatment of anterior callosal tumors 显示文摘D Angelo V Napolitano M Gorgoglione L 1997J Neurosurg Sci1997,41,1:1
13Laboratory observation of the dust-acoustic wave mode显示文摘Barkan A Merlino R L D′Angelo N 1995Physics of Plasma1995,2,10:1
14Pollution source identificationof accidental contamination in water distribution net-works 显示文摘Cristiana D C Angelo L 2008Journal of Water Resources Planning andManagement2008,134,2:1
15Expression of cell cycle markers and human papillomavirus infection in oral squamous cell carcinoma:use of fuzzy neural networks显示文摘Lo Muzio L D'Angelo M Procaccini M 2005Int J Cancer2005,115,5:1
16Endoscopic management of intra and paraventricular CSF cysts 显示文摘Tamburrini G D'Angelo L Patemoster G 2007Childs Nerv Syst2007,23,6:1
17Spatial patterns of nitrogen mineralization, fertilizer distribution and roots explain nitrate leaching from mature Amazonian oil palm plantation显示文摘Schroth G Rodrigues M R L D'Angelo S A 2000Soil Use and Management2000,16,3:1
18PPAR @ a me-diates the effects of the pesticide methyl thiophanateon liver of the lizard Podarcis sicula 显示文摘Buono S Cristiano L D'angelo B 2007ComparativeBiochemistry and Physiology Part C: Toxicology &Pharmacology2007,145,30:1
19Cl continuities detection intriangular meshes 显示文摘Angelo L D Stefano P D 2010Computer-Aided Design2010,42,9:1
20Effect of food on the bioavailability of pidotimod in healthy volunteers 显示文摘D' Angelo L de Ponti F Crema F 1994Arzneimittelforsch1994,44,12:1
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