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| 1 | CaMKII in cerebral ischemia显示文摘神经原上的 Ischemic 侮辱触发引起 Ca 导致 neuronal 房间死亡(excitotoxicity ) 的 2+ 超载的过多的、病理学的 glutamate 版本。Ca 2+/calmodulin (凸轮) 依赖者蛋白质 kinase II (CaMKII ) 是位于 neuronal 粘性下面并且学习的生理的有刺激性的 glutamate 信号的一个主要调停人。Glutamate 刺激在 T286 触发 CaMKII 的 autophosphorylation,使 kinase 成为 “ 的一个过程; autonomous”(从 Ca 2+ 刺激的部分活跃的独立人士) 并且那为 synaptic 的形式被要求粘性。最近的研究为侮辱以后的 neuroprotection 作为潜在的药目标也建议了自治 CaMKII 活动,在在 neuronal 文化的 glutamate 侮辱以后并且在在 vivo 的焦点的服的局部缺血以后。然而, CaMKII 和凸轮 kinase 家庭的另外的成员在 neuronal 死亡和幸存的规定被含有。这里,我们在 excitotoxicity 和服的局部缺血讨论过去的调查结果和凸轮 kinase 功能的可能的机制,与 CaMKII 和它的规定的一个焦点。 | Steven J COULTRAP Rebekah S VEST Nicole M ASHPOLE Andy HUDMON K Ulrich BAYEF | 2011 | Acta Pharmacologica Sinica2011，32，7： | 6 |
| 2 | Further geological and palaeoanthropological investigations at the Maludong hominin site, Yunnan Province, Southwest China显示文摘Three-dimensional mapping and section work undertaken by us in 2008 have identified 11 stratigraphic units at Maludong site.AMS radiocarbon dating of charcoal established an accurate and internally consistent age profile for the sequence of 17.8±0.2 ka to 13.2±0.1 ka.Archaeomagnetic analysis showed changes in externally derived pedogenically enhanced material consistent with a warming in climate between the cold period of Henrich Event 1 and the B lling-Aller d interstadial.Human remains recovered during the 1989 excavation were derived from a deposit dating to this interstadial,or between 14.3±0.3 ka and 13.5±0.1 ka.Anthropogenic features,including burnt rocks,baked sediment and thick charcoal and ash layers,were identified and examined through archaeomagnetic analysis.Two monkey fossils are described here,one of them being reassigned from Macaca robustus to M.aff.M.assamensis.They confirm the young age of the site and also show signs of anthropogenic alteration in the form of burning.Additional human cranial remains are reported for the first time and new data are provided for some specimens described previously.A range of new features is identified that strengthen the affinities of the Maludong remains to archaic humans.The presence of this globally unique mosaic of archaic and modern features raises important questions about human evolutionary history in East Asia during the Late Upper Pleistocene. | JI XuePing CURNOE Darren BAO ZhenDe HERRIES Andy I R FINK David ZHU YunSheng HELLSTROM John LUO Yun TACON Paul S C | 2013 | Chinese Science Bulletin2013，58，35： | 3 |
| 3 | Enhancement of surface wettability via micro-and nanostructures by single point diamond turning显示文摘Studies on surface wettability have received tremendous interest due to their potential applications in research and industrial processes. One of the strategies to tune surface wettability is modifying surface topography at micro-and nanoscales. In this research, periodic micro-and nanostructures were patterned on several polymer surfaces by ultra-precision single point diamond turning to investigate the relationships between surface topographies at the micro-and nanoscales and their surface wettability. This research revealed that single-point diamond turning could be used to enhance the wettability of a variety of polymers, including polyvinyl chloride(PVC), polyethylene 1000(PE1000), polypropylene copolymer(PP) and polytetrafluoroethylene(PFTE), which cannot be processed by conventional semiconductor-based manufacturing processes. Materials exhibiting common wettability properties(θ≈ 90°) changed to exhibit 'superhydrophobic' behavior(θ > 150°). Compared with the size of the structures, the aspect ratio of the void space between micro-and nanostructures has a strong impact on surface wettability. | Nicolás Cabezudo Jining Sun Behnam Andi Fei Ding Ding Wang Wenlong Chang Xichun Luo Ben B.Xu | 2019 | Nanotechnology and Precision Engineering2019，2，1： | 2 |
| 4 | Strategic guidelines for street canyon geometry to achieve sustainable street air quality显示文摘 | ANDY T C ELLEN S P SO | 2001 | Atmosphere Environment2001，35，： | 1 |
| 5 | Generalized p values in significance testing of hypotheses in the presence of nuisance parameters显示文摘 | TSUI K W WEERAH ANDI S | 1989 | Journal of the American Statistical Association1989，84，： | 1 |
| 6 | Effect of methy jasmonate on harpin-induced hypersensitive cell death,generation of hydrogen peroxide and expression of PAL mRNA in tobacco suspension cultured BY-2cells显示文摘 | Andi S Taguchi F Toyoda K | | 0，，04： | 1 |
| 7 | Dynamically vulcanized alloy innerliners显示文摘 | Donald S Tracey Andy H Tson | 2007 | Rubber World2007，236，6： | 1 |
| 8 | Preparation and Assembly of Colloidal Gold Nanoparticles in CTAB-stabilized Reverse Microemulsion显示文摘 | CHEN Feng-xi XU Guo-qin ANDY HOR T S | 2003 | Mater Lett2003，57，21： | 1 |
| 9 | High throughput real time electrochemical monitoring of LAMP for pathogenic bacte ria detection 显示文摘 | Mohammadali S Minhaz U A Andy N | 2014 | Biosensors and Bioelectronics2014，58，： | 1 |
| 10 | A study of the role of apoptotie cell death and cell cycle events mediating the mechanism of action of 6-hydroxycomnarin-3- carboxylat-osilver in human malignant hepatic cells 显示文摘 | Bhumika Thati Andy Noble Bernadette S C | 2007 | Cancer Letters2007，250，1： | 1 |
| 11 | Mycelial growth and substrate acidification of ectomycorrhizal fungi in response to different minerals 显示文摘 | Anna R Bjorn D L Andy F S T | 2004 | FEMS Microbiology Ecology2004，47，： | 1 |
| 12 | Static and dy-namic sliding mode control schemes for a permanent magnet step-per motor显示文摘 | MOHAMED Zribi HERBERTT S R ANDY Ngai | 2001 | International Journal of Control2001，74，2： | 1 |
| 13 | Pharmacovigilance activities in 55low-and middle-income countries显示文摘 | Sten O Shanthi N P Andy S | 2010 | Drug safety2010，33，8： | 1 |
| 14 | A view of cloud computing显示文摘 | MICHAEL A ARMANDO F REAN Q ANTHONY D J RANDY K ANDY K GUNHO L DAVID P ARIEL R ION S MATEI Z | 2010 | Communications of the ACM2010，53，4： | 1 |
| 15 | Efficient route to organometallic cage formation via C-H activation-dirocted muff component assembly accompanying aromatic guest encapsulation显示文摘 | HAN Y F UN Y J ANDY HOR T S ct al | 2012 | Organometallics2012，3，3： | 1 |
| 16 | Preparation and assembly of colloidal gold nanoparticles in CTAB-stabilized reverse microemulsion 显示文摘 | Xu G Q Andy T S | 2003 | Mater Lett2003，57，： | 1 |
| 17 | Two-Port vector network analyzer measurements up to 508 GHz 显示文摘 | ANDY F LORENE S GOUTAM C | 2007 | IEEE Trans Theory Tech2007，57，2： | 1 |
| 18 | Attention-deficit/hyperactivity disorder in preschool children:An investigation of validation based on visual attention performance显示文摘 | Mini T Xuemei S Andy B | 2009 | J Child Adolesc Psychopharmacol2009，19，2： | 1 |
| 19 | A study of the electrochemical properties of conduc- ting polymers for application in electrochemical capac- itors 显示文摘 | Rudge Andy I Raistrick an S Gottesfeld himshon | 1994 | Electrochim Acta1994，39，2： | 1 |
| 20 | How is post-industrial decline associated with the geography of physical activity? Evi- dence from the Health Survey for England显示文摘 | ESTHER R ANDY J HUMPHREY S | 2014 | Soc Sci Med2014，104，1： | 1 |
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