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| 1 | 为 Budd-Chiari 症候群的 caval 自体移植片由于劣等的静脉 cava 阻塞显示文摘 Transjugular intrahepatic portosystemic shunt (TIPS) is the standard treatment of Budd-Chiari syndrome (BCS) non responsive to medical therapy. However, patients with inferior vena cava (IVC) obstruction proximal to the atrium do not benefit from TIPS and a surgical approach is mandatory. We report the case of BCS due to intrapericardial IVC obstruction. We describe a novel surgical approach using a fresh caval homograft. An attempt to balloon dilatation of the IVC obstruction was complicated by right atrial disruption with tamponade and ventricular fibrillation. Lately, the patient successfully underwent a reconstruction of the cavo-atrial continuity by the interposition of a fresh caval homograft, a novel surgical approach never described before for BCS. Further follow-up revealed progressive reduction and resolution of ascites, and overall clinical improvement. IVC obstruction near to the atrium can be surgically approached with a new technique consisting in inferior vena cava resection and replacement with a caval homograft. | Andrea Mancuso Luigi Martinelli Luciano De Carlis Antonio Gaetano Rampoldi Giovanni Magenta Aldo Cannata Luca Saverio Belli | 2013 | World Journal of Hepatology2013，5，5： | 9 |
| 2 | Costs of laparoscopic and open liver and pancreatic resection:A systematic review显示文摘AIM:To study costs of laparoscopic and open liver and pancreatic resections,all the compiled data from available observational studies were systematically reviewed.METHODS:A systematic review of the literature was performed using the Medline,Embase,Pub Med,and Cochrane databases to identify all studies published up to 2013 that compared laparoscopic and open liver[laparoscopic hepatic resection(LLR)vs open liver resection(OLR)]and pancreatic[laparoscopic pancreatic resection(LPR)vs open pancreatic resection]resection.The last search was conducted on October 30,2013.RESULTS:Four studies reported that LLR was associated with lower ward stay cost than OLR(2972 USD vs 5291 USD).The costs related to equipment(3345USD vs 2207 USD)and theatre(14538 vs 11406)were reported higher for LLR.The total cost was lower in patients managed by LLR(19269 USD)compared to OLR(23419 USD).Four studies reported that LPR was associated with lower ward stay cost than OLR(6755vs 9826 USD).The costs related to equipment(2496USD vs 1630 USD)and theatre(5563 vs 4444)were reported higher for LPR.The total cost was lower in the LPR(8825 USD)compared to OLR(13380 USD).CONCLUSION:This systematic review support the economic advantage of laparoscopic over open approach to liver and pancreatic resection. | Paolo Limongelli Chiara Vitiello Andrea Belli Madhava Pai Salvatore Tolone Gianmattia del Genio Luigi Brusciano Giovanni Docimo Nagy Habib Giulio Belli Long Richard Jiao Ludovico Docimo | 2014 | World Journal of Gastroenterology2014，20，46： | 5 |
| 3 | Laparoscopic and open surgical treatment of left-sided pancreatic lesions: clinical outcomes and cost-effectiveness analysis显示文摘 | Paolo Limongelli Andrea Belli Gianluca Russo Luigi Cioffi Alberto D’Agostino Corrado Fantini Giulio Belli | 2012 | Surgical Endoscopy2012，，7： | 4 |
| 4 | Minimally invasive surgical treatment of intrahepatic cholangiocarcinoma:A systematic review显示文摘BACKGROUND Intrahepatic cholangiocarcinoma(ICC)is the second most common primary liver cancer and is characterized by an aggressive behavior and a dismal prognosis.Radical surgical resection represents the only potentially curative treatment.Despite the increasing acceptance of laparoscopic liver resection for surgical treatment of malignant liver diseases,its use for ICC is not commonly performed.In fact,to achieve surgical free margins a major resection and/or vascular and/or biliary reconstructions is often needed,as well as an associated lymph node dissection.AIM To review and summarize the current evidences on the minimally invasive resection of ICC.METHODS A systematic review of the literature based on the criteria predetermined by the investigators was performed from the 1st of January 2009 up to the 1st of January2021 in 4 databases(PubMed,Scopus,Google Scholar,and Cochrane databases).All retrospective and prospective studies reporting on the comparative outcomes of open vs minimally invasive treatment of ICC were included.An evaluation of manuscripts quality was achieved using Methodological Index for Non-Randomized Studies criteria and Newcastle-Ottawa Scale.RESULTS After a systematic search 9 studies fulfilled the inclusion criteria.Among the all 3012 included patients,2450 were operated by an open approach and 562 by a minimally invasive(laparoscopic)approach.Baseline characteristics,tumor characteristics,surgical outcomes and oncological outcomes were collected and analyzed,highlighting values with a statistical significant difference between patients treated with open or laparoscopic approach.Shorter hospital stay and lower intraoperative blood losses were reported by some Authors in minimally invasive surgery,on the contrary,in the open group there was a higher number of lymphadenectomies and a higher percentage of major hepatectomies.CONCLUSION Minimally invasive resection of ICC has some short-term benefits and it is safe and feasible only in selected centers with a high experience in laparoscopic approach for liver surgery.Minimally invasive surgery,actually,was considered mainly in patients with a tumor with a diameter<5 cm,without invasion of main biliary duct or main vessel and no vascular or biliary reconstructions were planned.Further studies are needed to elucidate its impact on long term oncologic outcomes. | Renato Patrone Francesco Izzo Raffaele Palaia Vincenza Granata Guglielmo Nasti Alessandro Ottaiano Gilda Pasta Andrea Belli | 2021 | World Journal of Gastrointestinal Oncology2021，13，12： | 3 |
| 5 | Hepatic resection for hepatocellular carcinoma in patients with C hild– P ugh’s A cirrhosis: is clinical evidence of portal hypertension a contraindication?显示文摘 | Roberto Santambrogio Michael D. Kluger Mara Costa Andrea Belli Matteo Barabino Alexis Laurent Enrico Opocher Daniel Azoulay Daniel Cherqui | 2012 | HPB2012，，1： | 2 |
| 6 | Laparoscopic hepatic resection for completely exophytic hepatocellular carcinoma on cirrhosis显示文摘 | Giulio Belli Corrado Fantini Alberto D’Agostino Andrea Belli Serena Langella | 2005 | Journal of Hepato - Biliary - Pancreatic Surgery2005，，6： | 1 |
| 7 | Laparoscopic left lateral hepatic lobectomy: a safer and faster technique显示文摘 | Giulio Belli Corrado Fantini Alberto D’Agostino Andrea Belli Luigi Cioffi Nadia Russolillo | 2006 | Journal of Hepato - Biliary - Pancreatic Surgery2006，，2： | 1 |
| 8 | 显示文摘 | Wagner Andrea Belli Renan Stotzel Christian | 2013 | The journal of Ddhesive Dentistry2013，15，5： | 1 |
| 9 | 显示文摘 | Lohbauer Ulrich Wagner Andrea Belli Renan | 2010 | Acta Biomaterialia2010，6，12： | 1 |
| 10 | Laparoscopic hand-assisted right hemihepatectomy by ultrasound-directed intrahepatic approach显示文摘 | Giulio Belli Alberto D’Agostino Corrado Fantini Andrea Belli Luigi Cioffi Paolo Limongelli Gianluca Russo | 2009 | Journal of Hepato-Biliary-Pancreatic Surgery2009，，： | 1 |
| 11 | Maintenance sunitinib or observation in metastatic pancreatic adenocarcinoma: A phase II randomised trial显示文摘 | Michele Reni Stefano Cereda Michele Milella Anna Novarino Alessandro Passardi Andrea Mambrini Giuseppe Di Lucca Giuseppe Aprile Carmen Belli Danova Marco Francesca Bergamo Enrico Franceschi Clara Fugazza Domenica Ceraulo Eugenio Villa | 2013 | European Journal of Cancer2013，，： | 1 |
| 12 | Novel uracil-based 2-aminoanilide and 2-aminoanilide-like derivatives: Histone deacetylase inhibition and in-cell activities显示文摘 | Antonello Mai Andrea Perrone Angela Nebbioso Dante Rotili Sergio Valente Maria Tardugno Silvio Massa Floriana De Bellis Lucia Altucci | 2008 | Bioorganic & Medicinal Chemistry Letters2008，，8： | 1 |
| 13 | Repeat liver surgery by laparoscopy for a malignant recurrence after previous open or laparoscopic resection显示文摘Aim:This paper reported the experience of one center on repeat laparoscopic liver surgery for metastasis and hepatocellular carcinoma(HCC)with a review of the literature.Methods:This retrospective study included 24 patients who underwent laparoscopic re-intervention(hepatic resection and radiofrequency ablation)for recurrent HCC in cirrhosis(n=17)and for recurrent malignant metastases(n=7)after a previous open or laparoscopic procedure.Patients were divided into two groups according to the fi rst surgical approach.Group 1 underwent open resection and laparoscopic procedure(7 patients),and Group 2 underwent laparoscopic resection and laparoscopic procedure(17 patients).Results:Mean operative time for re-intervention was signifi cantly longer for Group 1(220.14±80.06 min)than for Group 2(150±56.18 min;P=0.001),whereas the mean blood loss and mean hospital stay were comparable in both groups.According to Dindo-Clavien classifi cation,overall morbidity ranged between Grade I and IIIa and was similar in both groups.Conclusion:This study suggests that repeat laparoscopic surgery for recurrent hepatic malignant diseases in selected patients is a feasible and safe procedure with good short-term outcomes,but further prospective studies are needed to support these results. | Luigi Cioffi Andrea Belli Corrado Fantini Alberto D’Agostino Gianluca Russo Giulio Belli | 2015 | Hepatoma Research2015，1，1： | 1 |
| 14 | Thermal-induced Residual stresses affect the lifetime of zir- conia-veneercrowns显示文摘 | Renan Belli Roland Frankenberger Andreas Appeltb | 2013 | Dental Materials2013，29，： | 1 |
| 15 | Laparoscopic Segment VI Liver Resection using a Left Lateral Decubitus Position: A Personal Modified Technique显示文摘 | Giulio Belli Corrado Fantini Alberto D’Agostino Luigi Cioffi Paolo Limongelli Gianluca Russo Andrea Belli | 2008 | Journal of Gastrointestinal Surgery2008，，12： | 1 |
| 16 | Sorafenib for the treatment of recurrent hepatocellular carcinoma after liver transplantation: does mTOR inhibitors association augment toxicity?显示文摘 | Giovanni Perricone Andrea Mancuso Luca S. Belli Chiara Mazzarelli Claudio Zavaglia | 2014 | European Journal of Gastroenterology & Hepatology2014，，5： | 1 |
| 17 | Laparoscopic left lateral hepatic lobectomy: a safer and faster technique显示文摘 | Giulio Belli Corrado Fantini Alberto D’Agostino Andrea Belli Luigi Cioffi Nadia Russolillo | 2006 | Journal of Hepato - Biliary - Pancreatic Surgery2006，，2： | 1 |
| 18 | Hepatic resection for hepatocellular carcinoma in patients with C hild– P ugh’s A cirrhosis: is clinical evidence of portal hypertension a contraindication?显示文摘 | Roberto Santambrogio Michael D. Kluger Mara Costa Andrea Belli Matteo Barabino Alexis Laurent Enrico Opocher Daniel Azoulay Daniel Cherqui | 2012 | HPB2012，，1： | 1 |
| 19 | Adverse events affect sorafenib efficacy in patients with recurrent hepatocellular carcinoma after liver transplantation: experience at a single center and review of the literature显示文摘 | Claudio Zavaglia Aldo Airoldi Andrea Mancuso Marcello Vangeli Raffaella Viganò Gabriella Cordone Maria Gentiluomo Luca Saverio Belli | 2013 | European Journal of Gastroenterology & Hepatology2013，，2： | 1 |
| 20 | Local ablation of pancreatic tumors: State of the art and future perspectives显示文摘BACKGROUND Currently,the technologies most commonly used to treat locally advanced pancreatic cancer are radiofrequency ablation(RFA),microwave ablation,and irreversible(IRE)or reversible electroporation combined with low doses of chemotherapeutic drugs.AIM To report an overview and updates on ablative techniques in pancreatic cancer.METHODS Several electronic databases were searched.The search covered the years from January 2000 to January 2021.Moreover,the reference lists of the found papers were analysed for papers not indexed in the electronic databases.All titles and abstracts were analysed.RESULTS We found 30 studies(14 studies for RFA,3 for microwave therapy,10 for IRE,and 3 for electrochemotherapy),comprising 1047 patients,which were analysed further.Two randomized trials were found for IRE.Percutaneous and laparotomy approaches were performed.In the assessed patients,the median maximal diameter of the lesions was in the range of 2.8 to 4.5 cm.All series included patients unfit for surgical treatment,but Martin et al assessed a subgroup of patients with borderline resectable tumours who underwent resection with margin attenuation with IRE.Most studies administered chemotherapy prior to ablative therapies.However,several studies suggest that the key determinant of improved survival is attributable to ablative treatment alone.Nevertheless,the authors suggested chemotherapy before local therapies for several reasons.This strategy may not only downstage a subgroup of patients to curative-intent surgery but also support to recognize patients with biologically unfavourable tumours who would likely not benefit from ablation treatments.Ablation therapies seem safe based on the 1047 patients assessed in this review.The mortality rate ranged from 1.8%to 2%.However,despite the low mortality,the reported rates of severe post procedural complications ranged from 0%-42%.Most reported complications have been self-limiting and manageable.Median overall survival varied between 6.0 and 33 mo.Regarding the technical success rate,assessed papers reported an estimated rate in the range of 85%to 100%.However,the authors reported early recurrence after treatment.A distinct consideration should be made on whether local treatments induce an immune response in the ablated area.Preclinical and clinical studies have shown that RFA is a promising mechanism for inducing antigen-presenting cell infiltration and enhancing the systemic antitumour T-cell immune response and tumour regression.CONCLUSION In the management of patients with pancreatic cancer,the possibility of a multimodal approach should be considered,and conceptually,the combination of RFA with immunotherapy represents a novel angle of attack against this tumour. | Vincenza Granata Roberta Grassi Roberta Fusco Andrea Belli Raffaele Palaia Gianpaolo Carrafiello Vittorio Miele Roberto Grassi Antonella Petrillo Francesco Izzo | 2021 | World Journal of Gastroenterology2021，27，23： | 1 |
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