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| 1 | Dual destructive and protective roles of adaptive immunity in neurodegenerative disorders显示文摘Inappropriate T cell responses in the central nervous system(CNS)affect the pathogenesis of a broad range of neuroinflammatory and neurodegenerative disorders that include,but are not limited to,multiple sclerosis,amyotrophic lateral sclerosis,Alzheimer’s disease and Parkinson’s disease.On the one hand immune responses can exacerbate neurotoxic responses;while on the other hand,they can lead to neuroprotective outcomes.The temporal and spatial mechanisms by which these immune responses occur and are regulated in the setting of active disease have gained significant recent attention.Spatially,immune responses that affect neurodegeneration may occur within or outside the CNS.Migration of antigen-specific CD4+T cells from the periphery to the CNS and consequent immune cell interactions with resident glial cells affect neuroinflammation and neuronal survival.The destructive or protective mechanisms of these interactions are linked to the relative numerical and functional dominance of effector or regulatory T cells.Temporally,immune responses at disease onset or during progression may exhibit a differential balance of immune responses in the periphery and within the CNS.Immune responses with predominate T cell subtypes may differentially manifest migratory,regulatory and effector functions when triggered by endogenous misfolded and aggregated proteins and cell-specific stimuli.The final result is altered glial and neuronal behaviors that influence the disease course.Thus,discovery of neurodestructive and neuroprotective immune mechanisms will permit potential new therapeutic pathways that affect neuronal survival and slow disease progression. | Kristi M Anderson Katherine E Olson Katherine A Estes Ken Flanagan Howard E Gendelman R Lee Mosley | 2014 | Translational Neurodegeneration2014，3，1： | 8 |
| 2 | Image analysis and fracture geometry to characterize soil desiccation cracks显示文摘 | BEAR J U KEN T F ANDERSON S H | | 0，，： | 1 |
| 3 | Soft Tissue and Oc- clusal management in the surgical uprighting of impacted molars: technical note显示文摘 | Anderson Ken Murtagh Keith Sacks Harry G | 2012 | J Oral Maxillofac Surg2012，70，： | 1 |
| 4 | 显示文摘 | Gretchen Graef Ken Anderson Joanna Groza | 1996 | Materials and Engineering B1996，41，2： | 1 |
| 5 | Preglomerular structural changes in the renal vasculature显示文摘 | ANDERSON W P KEN M M EVANS R G | 1995 | Hyperten Blood Press1995，，： | 1 |
| 6 | Microstructural Size Effects in High-Strength High-Conductivity Cu-Cr-Nb Alloys 显示文摘 | Ken R Anderson Joanna R Groza | 2001 | Metallurgical and Materials Transactions A2001，32，5： | 1 |
| 7 | Pre-glomerular structural changes in the renal vasculature显示文摘 | Anderson WP Ken MM Evans RG | 1995 | Hypertension Blood Press1995，，： | 1 |
| 8 | Effects of the laccase-mediator system on the handsheets properties of two high kappa kraft pulps显示文摘 | Ken K Y Wong Kathryn B Anderson Paul Kibblewhite R | 1999 | Enzyme and Microbial Technology1999，25，： | 1 |
| 9 | Effects of the laccase-mediator system on the handsheet properties of two high kappa kraft pulps显示文摘 | Ken K Y Wong Kathryn B Anderson R Paul Kibblewhite | 1999 | Enzyme and Microbial Technology1999，，25： | 1 |
| 10 | Efects of the laeease mediator system on the hand sheet properties of two high kappa kraft pulps显示文摘 | Ken K Y Wong Kathryn B Anderson R Paul Kibble White | 1999 | Enzyme and Technology1999，，25： | 1 |
| 11 | Effects of the laccase mediator system on the hand sheet properties of two high kappa kraft pulps 显示文摘 | Ken K Y Wong Kathryn B Anderson R Paul Kibble White | 1999 | Enzyme and Technology1999，，25： | 1 |
| 12 | Enzymatic processing for pulp and paper manufacture 显示文摘 | Ken K Y Anderson W | 1999 | Appita J1999，52，6： | 1 |
| 13 | Antibiotic prophylaxis for GI endoscopy显示文摘 | Subhas Banerjee Bo Shen Todd H. Baron Douglas B. Nelson Michelle A. Anderson Brooks D. Cash Jason A. Dominitz S. Ian Gan M. Edwyn Harrison Steven O. Ikenberry Sanjay B. Jagannath David Lichtenstein Robert D. Fanelli Ken Lee Trina van Guilder Leslie E. Ste | 2008 | Gastrointestinal Endoscopy2008，，6： | 1 |
| 14 | Persistent Genetic Abnormalities in Barrett’s Esophagus After Photodynamic Therapy显示文摘 | Kausilia K. Krishnadath* Kenneth K. Wang* Ken Taniguchi? Thomas J. Sebo? Navtej S. Buttar* Marlys A. Anderson* Lori S. Lutzke* Wanguo Liu? | 2000 | Gastroenterology2000，，3： | 1 |
| 15 | Antibiotic prophylaxis for GI endoscopy显示文摘 | Subhas Banerjee Bo Shen Todd H. Baron Douglas B. Nelson Michelle A. Anderson Brooks D. Cash Jason A. Dominitz S. Ian Gan M. Edwyn Harrison Steven O. Ikenberry Sanjay B. Jagannath David Lichtenstein Robert D. Fanelli Ken Lee Trina van Guilder Leslie E. Ste | 2008 | Gastrointestinal Endoscopy2008，，6： | 1 |
| 16 | 生活观察带来营销机会显示文摘今天,企业人种志(Corporate Ethnography)研究不再只是为了创新,它已经成为企业全面了解客户及自身业务的关键所在。在我们英特尔公司(Intel)和其他一些公司,人种志研究承担起了新的职能,比如帮助企业制定战略和长期规划。 | 肯·安德森(Ken Anderson) 徐广彤(翻译) | 2009 | 商业评论2009，，5： | 0 |
| 17 | 仙履奇缘显示文摘中文名:仙履奇缘英文名:Cinderella导演:克莱德·吉诺尼米威尔弗雷德·杰克逊国家地区:美国出品公司:华特·迪士尼电影公司上映时间:1950年2月15日剧情简介《仙履奇缘》,又名《灰姑娘》,根据法国作家查尔斯·佩罗的同名童话故事《Cendrillon》改编,由克莱德·吉诺尼米、威尔弗雷德·杰克逊、汉密尔顿·卢斯科执导,艾琳·伍兹、威廉·菲普斯等人配音,1950年2月15日在美国首映。 | 夏尔·佩罗 Ken Anderson | 2017 | 电影画刊2017，0，6： | 0 |
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