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| 1 | 医保制度对医患关系影响的关键维度分析——基于中国、加拿大比较研究显示文摘目的探讨医保制度对我国医患关系产生影响的关键维度,通过对比中国与加拿大不同医保制度设计与要素安排及其对医患关系的影响,提出以医保制度重构为契机的医患关系改进政策建议。方法采用定量与定性相结合的分析方法对中国和加拿大的相关医保制度安排进行对比并提出合理政策建议。结果中国与加拿大在筹资机制、支付机制、报销机制、基金运行管理机制、立法监督机制以及异地就医等医保要素上所作出的不同制度安排,是造成两国医患关系不同结果的关键制度根源。结论构建和谐的医患关系绝不仅仅是医生与患者个人的责任,医保制度在其中起着不可忽视的作用。国际经验表明,合理的制度设计和要素安排能够为医患关系提供良好的制度环境。 | 王澜 吴群红 单凌寒 Ananya Parasor 李叶 康正 郝洁靓 潘庆霞 梁梓 | 2017 | 中国医院管理2017，37，4： | 8 |
| 2 | Perfusion computed tomography in renal cell carcinoma显示文摘Various imaging modalities are available for the diagnosis, staging and response evaluation of patients with renal cell carcinoma(RCC). While contrast enhanced computed tomography(CT) is used as the standard of imaging for size, morphological evaluation and response assessment in RCC, a new functional imaging technique like perfusion CT(p CT), goes down to the molecular level and provides new perspectives in imaging of RCC. p CT depicts regional tumor perfusion and vascular permeability which are indirect parameters of tumor angiogenesis and thereby provides vital information regarding tumor microenvironment. Also response evaluation using p CT may predate the size criteria used in Response Evaluation Criteria in Solid Tumors, as changes in the perfusion occurs earlier following tissue kinase inhibitors before any actual change in size. This may potentially help in predicting prognosis, better selection of therapy and more accurate and better response evaluation in patients with RCC. This article describes the techniques and role of p CT in staging and response assessment in patients with RCCs. | Chandan J Das Usha Thingujam Ananya Panda Sanjay Sharma Arun Kumar Gupta | 2015 | World Journal of Radiology2015，7，7： | 8 |
| 3 | Blunt pancreatic trauma: A persistent diagnostic conundrum?显示文摘Blunt pancreatic trauma is an uncommon injury but has high morbidity and mortality. In modern era of trauma care, pancreatic trauma remains a persistent challenge to radiologists and surgeons alike. Early detection of pancreatic trauma is essential to prevent subsequent complications. However early pancreatic injury is often subtle on computed tomography(CT) and can be missed unless specifically looked for. Signs of pancreatic injury on CT include laceration, transection, bulky pancreas, heterogeneous enhancement, peripancreatic fluid and signs of pancreatitis. Pan-creatic ductal injury is a vital decision-making parameter as ductal injury is an indication for laparotomy. While lacerations involving more than half of pancreatic parenchyma are suggestive of ductal injury on CT, ductal injuries can be directly assessed on magnetic resonance imaging(MRI) or encoscopic retrograde cholangio-pancreatography. Pancreatic trauma also shows temporal evolution with increase in extent of injury with time. Hence early CT scans may underestimate the extent of injures and sequential imaging with CT or MRI is important in pancreatic trauma. Sequential imaging is also needed for successful nonoperative management of pancreatic injury. Accurate early detection on initial CT and adopting a multimodality and sequential imaging strategy can improve outcome in pancreatic trauma. | Atin Kumar Ananya Panda Shivanand Gamanagatti | 2016 | World Journal of Radiology2016，8，2： | 8 |
| 4 | Sessile serrated adenomas:Demographic,endoscopic and pathological characteristics显示文摘AIM:To study the demographic and endoscopic characteristics of patients with sessile serrated adenoma(SSA) in a single center.METHODS:Patients with SSA were identified by review of the pathology database of Mayo Clinic Arizona from 2005 to 2007.A retrospective chart review was performed to extract data on demographics,polyp characteristics,presence of synchronous adenomatous polyps or cancer,polypectomy methods,and related complications.RESULTS:One hundred and seventy-one(2.9%) of all patients undergoing colonoscopy had a total of 226 SSAs.The mean(SE) size of the SSAs was 8.1(0.4) mm;42% of SSAs were ≤ 5 mm,and 69% were ≤ 9 mm.Fifty-one per cent of SSAs were located in the cecum or ascending colon.Approximately half of the patients had synchronous polyps of other histological types,including hyperplastic and adenomatous polyps.Synchronous adenocarcinoma was present in seven(4%) cases.Ninety-seven percent of polyps were removed by colonoscopy.CONCLUSION:Among patients with colon polyps,2.9% were found to have SSAs.Most of the SSAs were located in the right side and were safely managed by colonoscopy. | Suryakanth R Gurudu Russell I Heigh Giovanni De Petris Evelyn G Heigh Jonathan A Leighton Shabana F Pasha Isaac B Malagon Ananya Das | 2010 | World Journal of Gastroenterology2010，16，27： | 7 |
| 5 | 关于城市非正规化现象的规划认识论显示文摘在新世纪,许多重要的城市变革都发生在发展中国家,尤其是以城市贫民非法定居为主要表现形式的非正式化现象在大都市城市化中已经非常普遍。本文聚焦于城市非正式化现象,探讨了在正式的城市化秩序之外所出现的此类“不可规划”(unplannable)的状况,以及为了解决这些问题而面对的挑战。文中指出,规划师必须学会如何在这种预期之外的状态之下进行工作。这些政策认识不但对第三世界城市有益,而且对与社会公正分配相关的城市规划更具普遍意义。 | Ananya Roy 高璟 | 2005 | 国外城市规划2005，20，4： | 6 |
| 6 | 将非物质文化遗产与旅游业相连以赋权社区显示文摘文化旅游景点通常被视为是在促进乡愁,在那里,游客们被带回到过去,观看文物或历史古迹。它们往往被展示为传统仪式或艺术表演的静态意象。这种文化的商品化可能不是非常本真的,对民间艺术家来说,他们从中获得的经济收益往往微不足道。印度社会组织banglanatak dot com发起了'为生活的艺术'(Art for Life)倡议,旨在增加有着丰富非物质文化遗产资源的农村和地方社区的生活选择,一个成功的策略是将艺术家的村庄发展为文化旅游景区。本个案研究讲述了卷轴画家村Naya、Fakiri歌手村Gorbhanga和住着桑塔尔(Santhal)原住民的Tunta村,这些村庄都位于印度东部。在这些村庄中,游客们与艺术形式的实践者即活着的遗产进行互动,享受到一种民间艺术传统的真实经验。艺术家社区已经有能力创新旅游产品和管理旅游服务。节日已成为推进新旅游景点的重要工具,村落也已成为教育旅游目的地。在此过程中,艺术家的平均月收入大幅提高,同时社区的环境卫生和生活条件也得到改善。文化旅游给妇女和年轻人提供了体面的工作机会。本文指出:旅游发展策略可以复兴遗产,增强社区认同感和自豪感,给当地社区带来巨大经济收益,使社区成员拥有并管理旅游业而非成为旅游业的低端工作人员。 | Ananya Bhattacharya 沈燕 彭牧 | 2016 | 西北民族研究2016，，4： | 5 |
| 7 | Deficient DNA mismatch repair is associated with favorable prognosis in Thai patients with sporadic colorectal cancer显示文摘AIM:To determine the prognostic significance of deficient mismatch repair(d MMR) and BRAF V600 E in Thai sporadic colorectal cancer(CRC) patients.METHODS:We studied a total of 211 out of 405 specimens obtained from newly diagnosed CRC patients between October 1,2006 and December 31,2007 at Siriraj Hospital,Mahidol University.Formalinfixed paraffin-embedded blocks of CRC tissue samples w e re a n a l y ze d fo r d M M R b y d e t e c t i o n o f M M R protein expression loss by immunohistochemistry or microsatellite instability using polymerase chain reaction(PCR)-DHPLC.BRAF V600 E mutational analysis was performed in DNA extracted from the same archival tissues by two-round allele-specific PCR and analyzed by high sensitivity DHPLC.Associations between patient characteristics,MMR and BRAF status with diseasefree survival(DFS) and overall survival(OS) were determined by Kaplan-Meier survival plots and log-rank test together with Cox's proportional hazard regression.RESULTS:d MMR and BRAF V600 E mutations were identified in 31 of 208(14.9%) and 23 of 211(10.9%) tumors,respectively.d MMR was more commonly found in patients with primary colon tumors rather than rectal cancer(20.4% vs 7.6%,P =0.01),but there was no difference in MMR status between the right-sided and left-sided colon tumors(20.8% vs 34.6%,P = 0.24).d MMR was associated with early-stage rather than metastatic disease(17.3% vs 0%,P = 0.015).No clinicopathological features such primary site or tumor differentiation were associated with the BRAF mutation.Six of 31(19.3%) samples with d MMR carried the BRAFmutation,while 17 of 177(9.6%) with proficient MMR(p MMR) harbored the mutation(P = 0.11).Notably,patients with d MMR tumors had significantly superior DFS(HR = 0.30,95%CI:0.15-0.77; P = 0.01) and OS(HR = 0.29,95%CI:0.10-0.84; P = 0.02) compared with patients with p MMR tumors.By contrast,the BRAF V600 E mutation had no prognostic impact on DFS and OS.CONCLUSION:The prevalence of d MMR and BRAF V600 E in Thai sporadic CRC patients was 15% and 11%,respectively.The d MMR phenotype was associated with a favorable outcome. | Krittiya Korphaisarn Ananya Pongpaibul Chanin Limwongse Ekkapong Roothumnong Wipawi Klaisuban Akarin Nimmannit Artit Jinawath Charuwan Akewanlop | 2015 | World Journal of Gastroenterology2015，21，3： | 4 |
| 8 | Anisotropy Properties of Tissues: A Basis for Fabrication of Biomimetic Anisotropic Scaffolds for Tissue Engineering显示文摘Tissue engineering has been a subject of extensive scientific exploration in the last two decades making gradual inroads into clinical studies as well.Along with regenerative cells and growth factors,biomaterial scaffolds are integral to the development of a tissue engi neered construct.It is now appreciated that scaffolds should mimic the target tissue properties intimately in order to provide a micro-environment milieu that allows the seeded cells to differentiate into the desired tissue.Even from a structural viewpoint,mismatch between scaffold and native matrix properties can cause cell necrosis through mechanisms such as stress shielding.One of the key prop erties of most body tissues is that they exhib社anisotropy.However,most fabrication methods generate isotropic scaffolds and require specific modifications to produce anisotropic scaffolds.In the last decade,the advent of additive manufacturing and bioprinting has provided facile tools to fabricate scaffolds with desired anisotropy.On the other hand,a biomimetic scaffold can be designed only when target tissue anisotropy is well known to the tissue engineer.This review presents an overview of the anisotropic properties of different tissues,which will be critical for developing biomimetic engineered constructs.The traditional anatomical records do not adequately present these properties from the perspective of designing tissue engineering scaffolds.Subsequently,present state-of-the art in devel opment of anisotropic scaffolds as well as tissue constructs using different conventional and emerging fabrication techniques is discussed.It is expected that the readers will obtain a comprehensive reference on the research area by examining these two aspects juxtaposed to each other and gain key trends for fabrication of anisotropic scaffolds,plausibly with improved regenerative outcomes. | Pallab Datta Veena Vyas Santanu Dhara Amit Roy Chowdhury Ananya Barui | 2019 | Journal of Bionic Engineering2019，16，5： | 4 |
| 9 | <ce:link locator='fx1'/> American Gastroenterological Association (AGA) Institute Technical Review on Obscure Gastrointestinal Bleeding显示文摘 | Gottumukkala S. Raju Lauren Gerson Ananya Das Blair Lewis | 2007 | Gastroenterology2007，，5： | 4 |
| 10 | Anti-viral role of toll like receptor 4 in hepatitis B virus infection: An in vitro study显示文摘AIM Toll like receptors plays a significant anti-viral role in different infections. The aim of this study was to look into the role of toll like receptor 4(TLR4) in hepatitis B virus(HBV) infection.METHODS Real time PCR was used to analyze the transcription of TLR4 signaling molecules, cell cycle regulators and HBV DNA viral load after triggering the Hep G2.2.15 cells with TLR4 specific ligand. Nuclear factor(NF)-κB translocation on TLR4 activation was analyzed using microscopic techniques. Protein and cell cycle analysis was done using Western Blot and FACS respectively.RESULTS The present study shows that TLR4 activation represses HBV infection. As a result of HBV suppression, there are several changes in host factors which include partial release in G1/S cell cycle arrest and changes in host epigenetic marks. Finally, it was observed that anti-viral action of TLR4 takes place through the NF-κB pathway.CONCLUSION The study shows that TLR4 activation in HBV infection brings about changes in hepatocyte microenvironment and can be used for developing a promising therapeutic target in future. | Dipanwita Das Neelakshi Sarkar Isha Sengupta Ananya Pal Debraj Saha Manikankana Bandopadhyay Chandrima Das Jimmy Narayan Shivram Prasad Singh Runu Chakravarty | 2016 | World Journal of Gastroenterology2016，22，47： | 4 |
| 11 | Growth inhibition mediated by PSP94 or CRISP-3 is prostate cancer cell line specific显示文摘94 氨基酸(PSP94 ) 的能分泌的蛋白质被显示出与充满半胱氨酸的能分泌的蛋白质交往的前列腺 3 (CRISP-3 ) 在里面人的精液的血浆。有趣地, PSP94 表示被减少或在前列腺瘤的多数输了,而 CRISP-3 表示与正常前列腺织物相比是在前列腺癌症的 upregulated。为了获得单个角色的更好的理解,这些蛋白质在前列腺 tumourigenesis 和他们的相互作用的功能的关联有,我们宫外地在三根前列腺细胞线(PC3, WPE1-NB26 和 LNCaP ) 与 CRISP-3 一起表示了 PSP94 或 PSP94 并且执行了生长抑制试金。反向的抄写聚合酶链反应和西方的污点分析被用来为 PSP94 和 CRISP-3 表示屏蔽前列腺房间线。为人的 PSP94 和 CRISP-3 的哺乳动物的表示构造也被产生, recombinant 蛋白质的表示,本地化和分泌物是由西方的污点分析和 immunofluorescence 试金跟随的 transfection 的 assayed。PSP94 或 CRISP-3 的宫外的表示在房间生长上有的效果被 clonogenic 幸存试金追随者 transfection 学习。评估二蛋白质的合作表示的效果,表示了 PSP94 的 PC3 的稳定的克隆被产生。他们是随后有 CRISP-3 表示构造的 transfected 并且使遭到了到 clonogenic 幸存试金。我们的结果证明 PSP94 和 CRISP-3 能各在一根细胞线导致生长抑制特定的举止。尽管 CRISP-3-positive 房间线的生长被 PSP94 禁止,生长抑制由 CRISP-3 调停了没被 PSP94 的存在或缺席影响。这建议 CRISP-3 可以在前列腺 tumourigenesis 期间参予 PSP94 独立的活动。 | Bhakti R. Pathak Ananya A. Breed Vaishali H. Nakhawa Dhanashree D. Jagtap Smita D. Mahale | 2010 | Asian Journal of Andrology2010，12，5： | 3 |
| 12 | Predictors of mortality among HIV-infected patients initiating anti retroviral therapy at a tertiary care hospital in Eastern India显示文摘Objective:To assess early mortality and identify its predictors among the ART naive HIV-infected patients initiating anti retroviral therapy(ART) available free of cost at the ART Centres. Methods:A retrospective cohort analysis of routinely collected programme data was done for assessing mortality of all ART naive adult patients who received first-line ART at a government tertiary care hospital in eastern India during 1st March 2009 and 28th February 2010.Bivariate and multiple regression analyses of the baseline demographic,clinical and laboratory records using SPSS 15.0 were done to identify independent predictors of mortality.Results:The mortality rate at one year was estimated to be 7.66(95%CI 5.84-9.83) deaths/100 patient-years and more than 50%of the deaths occurred during first three months of ART initiation with a median time interval of 73 days.Tuberculosis was the major cause of death.ART naive patients with baseline serum albumin <3.5 mg/dL were eight(OR 7.9;95%CI:3.8-16.5) at risk of death than those with higher serum albumin levels and patients with CD4 count <I00 cells/μL were two times(OR 2.2; 95%CI:1.1-4.4) at risk of death compared to higher CD4 counts.Conclusions:Risk of mortality is increased when ART is initiated at advanced stages of immunosuppression denoted by low serum albumin levels and CD4 cell counts.This highlights the importance of early detection of HIV infection,early management of opportunistic infections including tuberculosis and timely initiation of the antiretroviral drugs in the resource-limited countries,now available free in the Indian national ART programme. | Ananya Bhowmik Subhasis Bhandari Rajyasree De Subhasish Kamal Guha | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，12： | 3 |
| 13 | Garden rue inhibits the arachidonic acid pathway, scavenges free radicals, and elevates FRAP: role in inflammation显示文摘AIM:In the present study,the anti-inflammatory and antioxidant activities of the methanol extract of Ruta graveolens leaves(RG-M) were evaluated using various in vivo and in vitro models.METHOD:For anti-inflammatory activity,RG-M was administered by the oral route(p.o.) in a carrageenan–induced paw edema model,and by the intraperitoneal route(i.p.) in an exudative inflammation model.In vitro inhibition of cyclooxygenase and lipoxygenase enzymes was evaluated.In vitro antioxidant activity was also examined.Endogenous antioxidant status was further evaluated by ferric reducing ability of plasma model.RESULTS:RG-M showed maximum inhibition of carrageenan-induced edema(100 mg·kg-1–33.36%; 200 mg·kg-1–45.32% and 400 mg·kg-1–56.28%).In the exudative inflammation model,a significant reduction in leukocyte migration(200 mg·kg-1–54.75% and 400 mg·kg-1–77.97%) and protein exudation(200 mg·kg-1–31.14% and 400 mg·kg-1–49.91%) were observed.RG-M also exhibited inhibition of COX–1(IC50 182.27 μg·mL-1) and COX–2(IC50 190.16 μg·mL-1) as well as 5–LOX(IC50 215.71 μg·mL-1).Antioxidant activity was significant with improved endogenous antioxidant status.CONCLUSION:The results demonstrated the anti-inflammatory and antioxidant activity of RG-M with potent inhibitory effects on the arachidonic acid pathways. | Manjir Sarma Kataki Bibhuti B Kakoti Biman Bhuyan Ananya Rajkumari Prakash Rajak | 2014 | Chinese Journal of Natural Medicines2014，12，3： | 3 |
| 14 | Plant Carbonic Anhydrases: Structures, Locations, Evolution, and Physiological Roles显示文摘碳的 anhydrases (CA ) 是锌 metalloenzymes 催化公司 2 和 HCO 3 的互变现象并且在自然是无所不在的。更高的植物包含三个 evolutionarily 不同的 CA 家庭, CA, CA,和 CA,在每个家庭被多重 isoforms 在所有种类代表的地方。CA 抄本的其他的拼接显得普通;因而,在种的功能的 CA isoforms 的数字可以超过基因的数字。CA 在众多的植物纸巾并且在不同细胞的地点被表示。最流行的 CA 是在叶绿体, cytosol,和线粒体的那些。在地点的这差异是在 CA 在植物起的许多生理、生物化学的作用的 paralleled。在在 C 3, C 的 CA 的这评论,数字和类型, 4, 和 crassulacean 酸新陈代谢(凸轮) 植物被考虑,并且 and CA 的角色简短被讨论。评论的剩余物集中于植物 CA 并且用种系发生的途径包括在种类之间的相当或相同的事物的鉴定,考虑内部 -- 并且蛋白质的细胞内部的本地化,与为选择的证据一起拼接形式。CA 织物特定的表示模式的当前的理解并且什么控制他们被考察,并且 CA 为被含有的生理的角色被介绍。 | Robert J. DiMario Harmony Clayton Ananya Mukhedee Martha Ludwig James V. Moroney | 2017 | Molecular Plant2017，10，1： | 3 |
| 15 | Endoscopic treatment of anastomotic biliary strictures after living donor liver transplantation: outcomes after maximal stent therapy显示文摘 | Ting-Hui Hsieh Kristin L. Mekeel Michael D. Crowell Cuong C. Nguyen Ananya Das Bashar A. Aqel Elizabeth J. Carey Thomas J. Byrne Hugo E. Vargas David D. Douglas David C. Mulligan M. Edwyn Harrison | 2013 | Gastrointestinal Endoscopy2013，，1： | 3 |
| 16 | Ellagic acid facilitates indomethacin-induced gastric ulcer healing via COX-2 up-regulation显示文摘导致消炎痛的胃的溃疡在试验性的老鼠模型由 ellagic 酸(EA ) 愈合的机制在我们的学习被描述。溃疡索引(UI ) 和 myeloperoxidase (军邮局) 胃纸巾的活动在消炎痛以后在第三天显示出最大的溃疡(18 mg/kg,单个剂量) 管理。UI 和军邮局活动的初步的观察建议 EA 拥有愈合溃疡的活动。另外的反溃疡参数象前列腺素 E2 的层次那样, cyclooxygenase (艇长) 1 和 2 酶,反煽动性的 cytokines [ interleukin ( IL ) -4 和-5], pro-angiogenic 因素例如脉管的 endothelial 生长因素, hepatocyte 生长因素( HGF ),并且 endothelial 生长因素( EGF )由消炎痛是下面调整的。为 3 天的处理转移了的 EA (7 mg/kg/day ) 导致消炎痛的支持 inflammatory 愈合的生物化学的参数站在一起。这些活动与 EA 的能力被相关改变愈合的 COX-2-dependent 小径。然而, EA 的愈合溃疡的活动被特定的 COX-2 禁止者, celecoxib,和 NS-398 的管理前损害。一起拿,这些结果建议 EA 处理加速溃疡由导致 IL-4 愈合, EGF/HGF 铺平并且提高 COX-2 表示。 | Ananya Chatterjee Sirshendu Chatterjee Smita Das Arpita Saha Subrata Chattopadhyay Sandip K.Bandyopadhyay | 2012 | Acta Biochimica et Biophysica Sinica2012，44，7： | 3 |
| 17 | American Gastroenterological Association (AGA) Institute Medical Position Statement on Obscure Gastrointestinal Bleeding显示文摘 | Gottumukkala S. Raju Lauren Gerson Ananya Das Blair Lewis | 2007 | Gastroenterology2007，，5： | 3 |
| 18 | Predictive significance of cancer related-inflammatory markers in locally advanced rectal cancer显示文摘BACKGROUND Locally advanced rectal cancer is treated using neoadjuvant chemoradiation(nCRT),followed by total mesorectal excision(TME).Tumor regression and pathological post-treatment stage are prognostic for oncological outcomes.There is a significant correlation between markers representing cancer-related inflammation,including high neutrophil-to-lymphocyte ratio(NLR),monocyteto-lymphocyte ratio(MLR),and platelet-to-lymphocyte(MLR)and unfavorable oncological outcomes.However,the predictive role of these markers on the effect of chemoradiation is unknown.AIM To evaluate the predictive roles of NLR,MLR,and PLR in patients with locally advanced rectal cancer receiving neoadjuvant chemoradiation.METHODS Patients(n=111)with locally advanced rectal cancer who underwent nCRT followed by TME at the Minimally Invasive Surgery Unit,Siriraj Hospital between 2012 and 2018 were retrospectively analyzed.The associations between post-treatment pathological stages,neoadjuvant rectal(NAR)score and the pretreatment ratios of markers of inflammation(NLR,MLR,and PLR)were analyzed.RESULTS Clinical stages determined using computed tomography,magnetic resonance imaging,or both were T4(n=16),T3(n=94),and T2(n=1).The NAR scores were categorized as high(score>16)in 23.4%,intermediate(score 8-16)in 41.4%,and low(score<8)in 35.2%.The mean values of the NLR,PLR,and MLR correlated with pathological tumor staging(ypT)and the NAR score.The values of NLR,PLR and MLR were higher in patients with advanced pathological stage and high NAR scores,but not statistically significant.CONCLUSION In patients with locally advanced rectal cancer,pretreatment NLR,MLR and PLR are higher in those with advanced pathological stage but the differences are not significantly different. | Kitinat Timudom Thawatchai Akaraviputh Vitoon Chinswangwatanakul Ananya Pongpaibul Pornpim Korpraphong Janjira Petsuksiri Suthinee Ithimakin Atthaphorn Trakarnsanga | 2020 | World Journal of Gastrointestinal Surgery2020，12，9： | 3 |
| 19 | Screening for anti-pancreatic lipase properties of 28 traditional Thai medicinal herbs显示文摘Objective:To screen the effect of 28 medicinal plants on inhibition of pancreatic lipase and evaluate the phytochemical contents of extracts.Methods:The ethanolic extracts of 28 traditional Thai herbal medicines were assayed for their in vitro activities against porcine pancreatic lipase using p-nitrophenyl butyrate as a substrate.Quantitative estimation of flavonoids,phenolics,and alkaloids was done.Results:Extracts from four herbs,Memecylon edule Roxb.,Garcinia vilersiana Pierre,Cryptolepis elegans Wall.and Phyllanthus chamaepeuce Ridl.,at a concentration of100 mg/m L,strongly inhibited porcine pancreatic lipase by 90.97%,92.04%,94.64%and95.38%,respectively.There was a significant positive correlation between phenolic content and inhibition activity.Inhibition activity was significantly correlated with flavonoid and with alkaloid contents.Conclusions:From this result,it could be concluded that herbs represent a rich of antipancreatic lipase compounds,in particular,Cryptolepis elegans Wall.and Phyllanthus chamaepeuce Ridl.It is suggested that the phytochemical compounds from these plants may be applied for the prevention and treatment of obesity or hyperlipidemia. | Ananya Dechakhamphu Nattapong Wongchum | 2015 | Asian Pacific Journal of Tropical Biomedicine2015，5，12： | 2 |
| 20 | Obscure Gastrointestinal Bleeding显示文摘Definition Obscure GI bleeding is de ned as bleeding from the GI tract that persists or recurs without an obvious etiology after esophagogastroduodenoscopy (EGD), colonoscopy, | Ananya Das | 2008 | 中国消化内镜2008，2，9： | 2 |
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