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| 1 | Phenolic profile of seventeen Portuguese wild mushrooms显示文摘 | Josiana A. Vaz Lillian Barros Anabela Martins Jorge Sá Morais M. Helena Vasconcelos Isabel C.F.R. Ferreira | 2010 | LWT - Food Science and Technology2010，，1： | 1 |
| 2 | Method to evaluate foaming performance显示文摘 | Anabela R Jose E Isabel S | 1998 | Journal of Food Engineering1998，36，： | 1 |
| 3 | Dehydration of xylose into furfural over micro-mesoporous sulfonic acid catalysts显示文摘 | Ana S Dias Martyn Pillinger Anabela A Valente | 2005 | Journal of Catalysis2005，229，2： | 1 |
| 4 | Liquid phase dehydration of D-xylose in the presence of keggin-type heteropolyacids显示文摘 | ANA S D MARTYN P ANABELA | 2005 | Applied Catalysis A:General2005，285，： | 1 |
| 5 | Exfoliated titanate, niobate and titanoniobate nanosheets as solid acid catalysts for the liquid-phase dehydration of d -xylose into furfural显示文摘 | Ana S. Dias Sérgio Lima Daniel Carriazo Vicente Rives Martyn Pillinger Anabela A. Valente | 2006 | Journal of Catalysis2006，，2： | 1 |
| 6 | Dehydration of xylose into furfural over micro-mesoporous sulfonic acid catalysts显示文摘 | Dias Ana S Pillinger Martyn Valente Anabela A | 2005 | Journal of Catalysis2005，229，： | 1 |
| 7 | A practical perspective on ulvan extracted from green algae 显示文摘 | Anabela A Rui A S RuiL Reis | 2013 | Journal of Applied Phycology2013，25，： | 1 |
| 8 | Recombinant human erythropoietin treatment protects the cardio-renal axis in a model of moderate chronic renal failure显示文摘 | Ana Margarida Teixeira Patrícia Garrido Paulo Santos Rui Alves Belmiro Parada Elísio Costa Anabela Almeida Edite Teixeira-Lemos José Sereno Rui Pinto Luís Belo Alice Santos-Silva Frederico Teixeira Flávio Reis | 2010 | Renal Failure2010，，9： | 1 |
| 9 | Bioactive properties and chemical composition of six walnut cuhivars显示文摘 | Jose A P Ivo O Anabela S | 2008 | Food and Chemical Toxicology2008，，46： | 1 |
| 10 | Dehydration of xylose into furfural over micro-mesoporous sulfonic acid catalysts 显示文摘 | Dias Ana S Pillinger Martyn Valente Anabela A | 2005 | Journal of Catalysis2005，229，2： | 1 |
| 11 | Mesoporous silica-supported 12-tungstophosphoric acid catalysts for the liquid phase dehydration of D-xylose 显示文摘 | Dias Ana S Pillinger Martyn Valente Anabela A | 2006 | Microporous and Mesoporous Materials2006，94，13： | 1 |
| 12 | Liquid phase dehydration of d-xylose in the presence of Keggintype heteropolyacids显示文摘 | Ana S Dias Martyn Pillinger Anabela A Valente | 2005 | Appl Cata A2005，285，： | 1 |
| 13 | Dehydration of xvlose into furfural over micro-mesoporous suIfonic acid eatalysts显示文摘 | DIAS Ana S Pillinger Martyn Valente Anabela A | 2005 | Journalof Catal ysls2005，229，： | 1 |
| 14 | Liquid phase dehydration of D-xylose in the presence of Keggin-type heteropolyacids显示文摘 | Ana S Dias Martyn Pillinger Anabela A Valente | 2005 | Applied Catalysis A2005，285，12： | 1 |
| 15 | The effects of ferulic and salicylic acids on Bacillus cereus and Pseudomonas fluorescens single- and dual-species biofilms显示文摘 | Madalena Lemos Anabela Borges Joana Teodósio Paula Araujo Filipe Mergulh?o Luís Melo Manuel Sim?es | 2013 | International Biodeterioration & Biodegradation2013，，： | 1 |
| 16 | Usefulness of serum C-reactive protein and calprotectin for the early detection of colorectal anastomotic leakage:A prospective observational study显示文摘BACKGROUND Colorectal anastomotic leakage(CAL)is one of the most dreaded complications after colorectal surgery,with an incidence that can be as high as 27%.This event is associated with increased morbidity and mortality;therefore,its early diagnosis is crucial to reduce clinical consequences and costs.Some biomarkers have been suggested as laboratory tools for the diagnosis of CAL.AIM To assess the usefulness of plasma C-reactive protein(CRP)and calprotectin(CLP)as early predictors of CAL.METHODS A prospective monocentric observational study was conducted including patients who underwent colorectal resection with anastomosis,from March 2017 to August 2019.Patients were divided into three groups:G1–no complications;G2–complications not related to CAL;and G3–CAL.Five biomarkers were measured and analyzed in the first 5 postoperative days(PODs),namely white blood cell(WBC)count,eosinophil cell count(ECC),CRP,CLP,and procalcitonin(PCT).Clinical criteria,such as abdominal pain and clinical condition,were also assessed.The correlation between biomarkers and CAL was evaluated.Receiver operating characteristic(ROC)curve analysis was used to compare the accuracy of these biomarkers as predictors of CAL,and the area under the ROC curve(AUROC),specificity,sensitivity,positive predictive value,and negative predictive value(NPV)during this period were estimated.RESULTS In total,25 of 396 patients developed CAL(6.3%),and the mean time for this diagnosis was 9.0±6.8 d.Some operative characteristics,such as surgical approach,blood loss,intraoperative complications,and duration of the procedure,were notably related to the development of CAL.The length of hospital stay was markedly higher in the group that developed CAL compared with the group with complications other than CAL and the group with no complications(median of 21 d vs 13 d and 7 d respectively;P<0.001).For abdominal pain,the best predictive performance was on POD4 and POD5,with the largest AUROC of 0.84 on POD4.Worsening of the clinical condition was associated with the diagnosis of CAL,presenting a higher predictive effect on POD5,with an AUROC of 0.9.WBC and ECC showed better predictive effects on POD5(AUROC=0.62 and 0.7,respectively).Those markers also presented a high NPV(94%-98%).PCT had the best predictive effect on POD5(AUROC=0.61),although it presented low accuracy.However,this biomarker revealed a high NPV on POD3,POD4,and POD5(96%,95%,and 96%,respectively).The mean CRP value on POD5 was significantly higher in the group that developed CAL compared with the group without complications(195.5±139.9 mg/L vs 59.5±43.4 mg/L;P<0.00001).On POD5,CRP had a NPV of 98%.The mean CLP value on POD3 was significantly higher in G3 compared with G1(5.26±3.58μg/mL vs 11.52±6.81μg/mL;P<0.00005).On POD3,the combination of CLP and CRP values showed a high diagnostic accuracy(AUROC=0.82),providing a 5.2 d reduction in the time to CAL diagnosis.CONCLUSION CRP and CLP are moderate predictors of CAL.However,the combination of these biomarkers presents an increased diagnostic accuracy,potentially decreasing the time to CAL diagnosis. | Nuno J G Rama Marlene C C Lages Maria Pedro S Guarino Óscar Lourenço Patrícia C Motta Lima Diana Parente Cândida S G Silva Ricardo Castro Ana Bento Anabela Rocha Fernando Castro-Pocas João Pimente | 2022 | World Journal of Gastroenterology2022，28，24： | 1 |
| 17 | Liquid phase dehydration of D-xylose in the presence of Keggin-type heteropolyacids显示文摘 | DIAS ANA S PILLINGER MARTYN ANABELA A | 2005 | Applied Catalysis A: General2005，285，12： | 1 |
| 18 | Mesoporous silica-supported 12- tungstophosphoric acid catalysts for the liquid phase dehydration of d-xylose 显示文摘 | Ana S D Martyu P Anabela A V | 2006 | Microporous and Mesopomus Materials2006，94，： | 1 |
| 19 | ^(222)Rn calibration procedure for water analyses by liquid scintillation counting显示文摘Purpose Among the several methods to measure ^(222)Rn in water,the liquid scintillation counting(LSC)technique is one of the most sensitive and widely used when analysing non-saline waters by liquid extraction,providing excellent accuracy,precision and low-level detection limits.When using the liquid scintillation counter Tri-Carb 3170 TR/SL(Perkin-Elmer)it is not possible to make an automatic determination of the alpha/beta discrimination parameter,being necessary to evaluate the pulse decay discriminator(PDD)value manually to the ^(222)Rn determination.In this work,we describe the steps to perform the calibration of that type of equipment.Methods The method consists in the preparation of standard samples from a ^(226)Ra certified standard solution and the adjustment of the PDD value by hand until the percentage of alpha events reaches a plateau of a near-constant fraction of total events.The process consists in taking several measures between PDD 80 and 200 with 15 min counting time each.Within the plateau,the alpha/beta ratio was used to determine the plateau final range as well as the optimum PDD value.After that,the calibration standards and blanks were measured and the region of interest(ROI)was established by finding the maximum value for the figure of merit(FOM)in the upper and lower limits.Results The optimal PDD value of 148 was established by the alpha/beta ratio,and after that,it was possible to measure ^(226)Ra standards to perform the calibration.An efficiency of(9.758±0.035)×1^(0-1) was obtained.In routine measurements,a detection limit of about 0.50 Bq L^(-1) is achieved for a 120 min counting time.To evaluate the uncertainty budget,the uncertainties of the net count rate,the efficiency,the sample amount and the decay correction factor were considered.Conclusions A method was developed for the calibration of LSC Tri-Carb 3170 TR/SL with the optimization of the PDD using a ^(226)Ra standard solution.The acquisition to obtain the plot of the variation of the events fraction in each window(alpha and beta)in function of PDD allowed to evaluate a plateau where the fraction of events was at a minimum.Afterwards,it was possible to measure the set of ^(226)Ra standards after the equilibrium with ^(222)Rn and determine the efficiency for ^(222)Rn with a detection limit of about 0.50 Bq L^(-1) in routine analyses. | Ana Rita Gomes Sérgio Dias Anabela Mourato Joao Abrantes Mário Reis | 2023 | Radiation Detection Technology and Methods2023，7，2： | 0 |
| 20 | Development of a warning score for early detection of colorectal anastomotic leakage:Hype or hope?显示文摘BACKGROUND Colorectal anastomotic leakage(CAL),a severe postoperative complication,is associated with high morbidity,hospital readmission,and overall healthcare costs.Early detection of CAL remains a challenge in clinical practice.However,some decision models have been developed to increase the diagnostic accuracy of this event.AIM To develop a score based on easily accessible variables to detect CAL early.METHODS Based on the least absolute shrinkage and selection operator method,a predictive classification system was developed[Early ColoRectAL Leakage(E-CRALL)score]from a prospective observational,single center cohort,carried out in a colorectal division from a non-academic hospital.The score performance and CAL threshold from postoperative day(POD)3 to POD5 were estimated.Based on a precise analytical decision model,the standard clinical practice was compared with the E-CRALL adoption on POD3,POD4,or POD5.A cost-minimization analysis was conducted,on the assumption that all alternatives delivered similar health-related effects.RESULTS In this study,396 patients who underwent colorectal resection surgery with anastomosis,and 6.3%(n=25)developed CAL.Most of the patients who developed CAL(n=23;92%)were diagnosed during the first hospital admission,with a median time of diagnosis of 9.0±6.8 d.From POD3 to POD5,the area under the receiver operating characteristic curve of the E-CRALL score was 0.82,0.84,and 0.95,respectively.On POD5,if a threshold of 8.29 was chosen,87.4%of anastomotic failures were identified with E-CRALL adoption.Additionally,score usage could anticipate CAL diagnosis in an average of 5.2 d and 4.1 d,if used on POD3 and POD5,respectively.Regardless of score adoption,episode comprehensive costs were markedly greater(up to four times)in patients who developed CAL in comparison with patients who did not develop CAL.Nonetheless,the use of the E-CRALL warning score was associated with cost savings of€421442.20,with most(92.9%)of the savings from patients who did not develop CAL.CONCLUSION The E-CRALL score is an accessible tool to predict CAL at an early timepoint.Additionally,ECRALL can reduce overall healthcare costs,mainly in the reduction of hospital costs,independent of whether a patient developed CAL. | Nuno J G Rama Óscar Lourenço Patrícia C Motta Lima Maria Pedro S Guarino Diana Parente Ricardo Castro Ana Bento Anabela Rocha Fernando Castro-Poças João Pimentel | 2022 | World Journal of Gastrointestinal Surgery2022，14，11： | 0 |
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