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| 1 | Management of hepatitis C in patients with chronic kidney disease显示文摘Hepatitis C virus(HCV) infection is highly prevalent among chronic kidney disease(CKD) subjects under hemodialysis and in kidney transplantation(KT) recipients, being an important cause of morbidity and mortality in these patients. The vast majority of HCV chronic infections in the hemodialysis setting are currently attributable to nosocomial transmission. Acute and chronic hepatitis C exhibits distinct clinical and laboratorial features, which can impact on managementand treatment decisions. In hemodialysis subjects, acute infections are usually asymptomatic and anicteric; since spontaneous viral clearance is very uncommon in this context, acute infections should be treated as soon as possible. In KT recipients, the occurrence of acute hepatitis C can have a more severe course, with a rapid progression of liver fibrosis. In these patients, it is recommended to use pegylated interferon(PEG-IFN) in combination with ribavirin, with doses adjusted according to estimated glomerular filtration rate. There is no evidence suggesting that chronic hepatitis C exhibits a more aggressive course in CKD subjects under conservative management. In these subjects, indication of treatment with PEG-IFN plus ribavirin relies on the CKD stage, rate of progression of renal dysfunction and the possibility of a preemptive transplant. HCV infection has been associated with both liver disease-related deaths and cardiovascular mortality in hemodialysis patients. Among those individuals, low HCV viral loads and the phenomenon of intermittent HCV viremia are often observed, and sequential HCV RNA monitoring is needed. Despite the poor tolerability and suboptimal efficacy of antiviral therapy in CKD patients, many patients can achieve sustained virological response, which improve patient and graft outcomes. Hepatitis C eradication before KT theoretically improves survival and reduces the occurrence of chronic graft nephropathy, de novo glomerulonephritis and post-transplant diabetes mellitus. | Roberto J Carvalho-Filho Ana Cristina CA Feldner Antonio Eduardo B Silva Maria Lucia G Ferraz | 2015 | World Journal of Gastroenterology2015，21，2： | 4 |
| 2 | Colonic duplication in an adult mimicking a tumor of pancreas显示文摘Duplications of the alimentary tract are uncommon congenital malformations that can present diagnostic difficulties. We report a rare case of a cystic colonic duplication in a female adult. Preoperative investigations were suggestive of pancreatic tumor. The diagnosis was established based on the histopathological examination of the resected specimen. We concluded that, though uncommon, intestinal duplication should be considered in differential diagnosis of abdominal mass. | Fabiana Pirani Carneiro Maria de Nazareth Sobreira Ana Emília B de Azevedo Andréa Pedrosa Ribeiro Alves Karina Martins Campos | 2008 | World Journal of Gastroenterology2008，14，6： | 3 |
| 3 | Influence of the ethylene-(methacrylic acid)-Zn^2+ ionomer on the thermal and mechanical properties of blends of poly (propylene) (PP)/ethylene-(vinyl alcohol) copoly- mer (EVOH) 显示文摘 | MARIA J A ANA A LU1S B | 2006 | European Polymer Journal2006，42，： | 1 |
| 4 | Recurrent Pain in Children and Adolescents显示文摘 | Ana Maria B | 2003 | Jornal de Pediatria2003，79，1： | 1 |
| 5 | Polymorphisms in exons 6 and 7 of the ABO locus and their association with venous thrombosis in young Brazilian patients显示文摘 | Sabrina G Paiva Adriano P Sabino Maria G Carvalho Daniel D Ribeiro Karina B Gomes Mariana S Santos Marina S Oliveira Geralda G Lages Luci MS Dusse Ana Paula Fernandes | 2009 | Blood Coagulation & Fibrinolysis2009，，2： | 1 |
| 6 | Overnight lowering of free fatty acid with Acipimox improves insulin resistance and glucose toler ance in obese diabetic and nondiabetic subjects 显示文摘 | Guenther B Maria ERS | 1999 | Diabetes1999，48，： | 1 |
| 7 | Mitochondrial-targeted protective properties of isolated diterpenoids from sideritis spp, in response to the deleterious changes induced by H2O2 显示文摘 | Elena G B Ana I D Maria E C | 2013 | Nat Prod2013，76，5： | 1 |
| 8 | Influence of temperature, pH and ionic strength on the production of isoflavone - rich soy protein isolates 显示文摘 | ANA C L B FRANCO M L MARIA I G | 2006 | Food Chemistry2006，98，： | 1 |
| 9 | Arabidopsis and tobacco plants ectopically expressing the soybean antiquitin-like ALDH7 gene display enhanced tolerance to drought,salinity,and oxidative stress显示文摘 | Simone M R Maxuel O A Ana P S G Fabio M D Maria C B P Elizabeth P B F | | 0，，： | 1 |
| 10 | Ovemight lowing of free fatty aeid with Acipimox improves insulin resistance and glucose tolerance in obese diabetic and nondiabetic subjeets 显示文摘 | Ana TM Guenther B Maria ERS | 1999 | Diabetes1999，48，8： | 1 |
| 11 | Structural and magnetic properties of Ln(Ⅲ) complexes with diimines and crotonato as a bridging ligand 显示文摘 | Ana M A Ricarclo B Maria T G | 2004 | Inorg Chim Acta2004，357，： | 1 |
| 12 | Chromosome number in Bromeliaceae显示文摘 | Ana L P C José G A A Moema C B Jorge C S A Maria L S G | 2000 | Genetic and Molecular Biology2000，23，1： | 1 |
| 13 | Polymer blends based On polyolefin elastomer and polypropylene 显示文摘 | Ana Lcia N Da Silva Maria Ines B Tavares Daniel P Politano | 1997 | J Appl polym Sei1997，66，： | 1 |
| 14 | Sucrulytic activities in relation to sink strength and carbohydrate composition in tomato fruit growing under salinity显示文摘 | MARIA E B ANA M S C MARIA C B | 1996 | Plant Science1996，，118： | 1 |
| 15 | Sociodemographic Determinants of Prevalence and Incidence of Helicobacter pylori Infection in Portuguese Adults显示文摘 | Joana Bastos Bárbara Peleteiro Rita Barros Luís Alves Milton Severo Maria Fátima Pina Hugo Pinto Sandra Carvalho Ana Marinho Jo?o T. Guimar?es Ana Azevedo Carlo Vecchia Henrique Barros Nuno Lunet | 2013 | Helicobacter2013，，6： | 1 |
| 16 | In vivo growth-inhibition of Sarcoma180 by an α-(1→4)-glucan-β-(1 →6)-glucan-protein complex polysaccharide obtained from Agaricus blazei Murill显示文摘 | MARIA L C G DANIEL P B ANA P N N A | 2009 | J Nat Med2009，63，： | 1 |
| 17 | Ternary interpenetrating networks of polyurethane - poly ( methyl methacrylate) -silica: preparation by the sol - gel process and characterization of films 显示文摘 | Gabriela B Martina M Ana Maria M | 2006 | European Polymer Journal2006，42，11： | 1 |
| 18 | Aerobic exercise reduces oxidative stress and improves vascular changes of small mesenteric and coronary arteries in hypertension显示文摘 | Fernanda R Roque Ana M Briones Ana B García‐Redondo María Galán Sonia Martínez‐Revelles Maria S Avenda?o Victoria Cachofeiro Tiago Fernandes Dalton V Vassallo Edilamar M Oliveira Mercedes Salaices | 2013 | Br J Pharmacol2013，，3： | 1 |
| 19 | β-Glucosidase activity in wine yeasts: Application in enology显示文摘 | Maria A V Juan F uI Ana I B P | 2007 | Enzyme and Microbial Technology2007，40，3： | 1 |
| 20 | Quereetin induces ap- optosis via caspase activation, regulation of Bcl-2, and inhibition of PI-3-Kinase/Akt and ERK pathways in a human hepatoma cell line (HepG2) 显示文摘 | Ana Belen GS Maria AM Laura B | 2006 | JNutr2006，136，11： | 1 |
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