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| 1 | Rhabdomyolysis after midazolam administration in a cirrhotic patient treated with atorvastatin显示文摘The administration of statins in patients with liver disease is not an absolute contraindication. Hepatotoxicity is a rare and often dose-related event and in the literature there are only a few described cases of fatal rhab-domyolysis in patients with chronic liver disease after statin administration. During treatment with 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors,the factors responsible for myopathy may either be related to the patient,or due to interactions with other medications that are metabolic substrates of the same isozymes and therefore able to increase blood statin concentration. The most important side effects consist of increased transaminase levels,abdominal pain or muscle weakness,increased serum levels of creatine kinase and rhabdomyolysis. In this article we report a case of fatal rhabdomyolysis with acute renal failure after gastric endoscopy,where midazolam was used as a sedation agent in a patient with chronic liver disease treated with a high dose of atorvastatin. Therefore,we suggest paying particular attention to the potential risks of associating atorvastatin and midazolam in patients with chronic liver disease who need to undergo gastric endoscopy. | Antonietta Gigante Gianluca Di Lazzaro Giraldi Maria Ludovica Gasperini Biagio Barbano Marta Liberatori Liborio Sardo Francesca Di Mario Antonella Giorgi Filippo Rossi-Fanelli Antonio Amoroso | 2014 | World Journal of Gastrointestinal Pharmacology and Therapeutics2014，5，3： | 6 |
| 2 | 砾性土液化评价方法的通用性和可靠性研究显示文摘以2008年汶川地震液化震害调查资料为背景,基于操作性和经济性上具有显著优势的中国动力触探试验(DPT)而提出的砾性土液化评价方法,包括砾性土层液化触发条件以及判别公式(CYY公式),理论上已经得到国内外同行的认可,但其通用性和可靠性尚需检验。以5个国家29个历史地震砾性土场地中美联合勘测为基础,研究DPT技术、砾性土层液化触发条件和CYY公式在不同国家、不同地震和不同场地的适用性和可靠性问题,其中,成都平原14个砾性土场地的勘测与数据处理由中方完成,美国、意大利、新西兰、厄瓜多尔等15个砾性土场地的勘测与数据处理由美方Rollins教授主导完成,均为新的测试检验点。结果表明:中国动力触探标准探头在不同国家、不同砾性土场地上测试具有可行性,可以有效穿透20 m的砾性土场地,动探击数可作为砾性土液化评价的核心指标,同时亦可扩展到砾性土层的力学性能评价;不同国家、不同砾性土液化场地上,均存在不排水或排水不畅的埋藏条件,符合砾性土层液化触发条件要求;对动力触探击数进行锤击能量、有效上覆压力等修正后,CYY公式在不同国家、不同地震、不同砾性土液化场地的判别成功率约96%,具有较高可靠性。以2008年汶川地震砾性土液化为背景、以动力触探锤击数为基本指标的砾性土液化评价方法,具有国际通用的可行性。 | 曹振中 Kyle M.Rollins 袁晓铭 T.Leslie Youd Michael Talbot Jashod Roy Sara Amoroso | 2019 | 岩土工程学报2019，41，9： | 5 |
| 3 | Changing trends in corneal graft surgery: a ten-year review显示文摘AIM:To review indications and corneal tissue use for penetrating and lamellar surgery between 2002 and 2011.·METHODS:The surgical reports of corneal grafts performed during 2002-2011,using tissues supplied by the Eye Bank of Piedmont(Italy),were reviewed retrospectively.Patient demographic data,date of intervention,indication for surgery,and surgical technique used were recorded.Surgical techniques included penetrating keratoplasty(PK),deep anterior lamellar keratoplasty(DALK)and endothelial keratoplasty(EK).Theχ2test was used to compare the distribution of indications and types of surgical technique used,for corneal grafts done during 2002-2006 versus those done during 2007-2011.·RESULTS:The number of corneal grafts increased by30.7%from 2002-2006 to 2007-2011(from 1567 to 2048).Comparing the two periods,both main indications and surgical techniques changed significantly.In 2007-2011,the proportion of interventions for aphakic/pseudophakic bollous keratopathy(from 16.8%to 21.3%),graft failure(from 16.4%to 19.1%)and Fuchs endothelial dystrophy(from 12.8%to 16.7%)all increased significantly(P<0.05),while those for keratoconus decreased significantly(from35.6%to 27.3%;P<0.001).In 2007-2011,the proportion of PK decreased significantly(from 92.4%to 57.2%;P<0.001)while that of EK and DALK went from 0.4%to30.2%(P<0.001)and from 7.2%to 12.6%(P<0.001)respectively.·CONCLUSION:During 2002-2011 the number of interventions increased significantly for corneal endothelial diseases and graft failure.The growing demand for interventions for these diseases corresponded to the widespread adoption of EK techniques.The use of DALK also increased,but more moderately than EK procedures. | Ugo de Sanctis camilla alovisi Luigi Bauchiero Guido Caramello Gianfranco Girotto Claudio Panico Luisa Vinai Federico Genzano Antonio Amoroso federico grignolo | 2016 | International Journal of Ophthalmology(English edition)2016，9，1： | 3 |
| 4 | Targeting neuronal nitric oxide synthase as a valuable strategy for the therapy of neurological disorders显示文摘The management of neurological disorders have huge and increasing human and economic costs.Despite this,there is a scarcity of effective therapeutics,and there is an extreme urgency for new and real treatments.In this short review we analyze some promising advancements in the search of new bioactive molecules targeting neuronal nitric oxide synthase(nNOS),an enzyme deputed to the biosynthesis of nitric oxide(NO).In different conditions of neuronal damages,this molecule is overproduced,contributing to the pathogenesis and progression of neuronal diseases.Two main approaches to modulate nNOS are discussed:a first one consisting in the direct inhibition of the enzyme by means of small organic molecules,which can be also active against other different targets involved in such diseases.A second section is dedicated to molecules able to prevent the formation of the ternary complex N-methyl-D-aspartate(NMDA)-type glutamate receptors,postsynaptic density-95(PSD95) protein-nNOS,which is necessary to activate the latter for the biosynthesis of NO. | Cristina Maccallini Rosa Amoroso | 2016 | Neural Regeneration Research2016，11，11： | 3 |
| 5 | Optical coherence tomography angiography in retinal cavernous hemangioma显示文摘Dear Editor,Cavernous hemangiomas of the retina are rare benign vascular tumors,commonly diagnosed in children and young adults.They are characterized by dilated blood vessels that form cavities or caverns through which the blood flow is very low or virtually absent[1].Retinal lesions may | Gilda Cennamo Francesca Amoroso Domenico Solari Mariacristina Alfier Giuseppe de Crecchio | 2017 | International Journal of Ophthalmology(English edition)2017，10，12： | 3 |
| 6 | Bevacizumab with FOLFOXIRI (irinotecan, oxaliplatin, fluorouracil, and folinate) as first-line treatment for metastatic colorectal cancer: a phase 2 trial显示文摘 | Gianluca Masi Fotios Loupakis Lisa Salvatore Lorenzo Fornaro Chiara Cremolini Samanta Cupini Andrea Ciarlo Francesca Del Monte Enrico Cortesi Domenico Amoroso Cristina Granetto Gabriella Fontanini Elisa Sensi Cristiana Lupi Michele Andreuccetti Alfredo Fa | 2010 | Lancet Oncology2010，，9： | 2 |
| 7 | Systemic lupus erythemato-sus and renal involvement:which role of citokines expression显示文摘 | Gigante A Amoroso D Ferri F | 2006 | Eur Rev Med Pharmacol Sci2006，10，5： | 1 |
| 8 | An efficient and reusable catalyst based on Pd/CeOz for the room temperature aerobic Suzuki-Miyaura reaction in water/ethanol显示文摘 | AMOROSO F COLUSSI ZOTTO A DE | 2010 | Journal of Molecular Catalysis A: Chemical2010，315，19： | 1 |
| 9 | Pathophysiology of vascular endothelium and circulating platelets: implications for coronary revascularisation and treatment显示文摘 | van Veldhuisen DJ Tio RA | 2001 | Int J Cardiol2001，79，： | 1 |
| 10 | 显示文摘 | Paggi A Amoroso A Ferri GM | 1998 | Eur Rev Med Pharmacol Sci1998，2，1： | 1 |
| 11 | Microarray-based genetics of cardiac malformations显示文摘 | I Miertus J Amoroso A | 2001 | Ital Heart J2001，2，8： | 1 |
| 12 | Correlation between virus genotype and chronicity rate in acute hepatitis C显示文摘 | Amoroso P Rapicetta M Tosti ME | 1998 | J Hepatol1998，28，6： | 1 |
| 13 | Genetic factors in mother-to-child transmission of HCV infection显示文摘 | Elena Bevilacqua Annalisa Fabris Paolo Floreano Lucy Pembrey Marie-Louise Newell Pier-Angelo Tovo Antonio Amoroso | 2009 | Virology2009，，1： | 1 |
| 14 | Bare metal stents, durable polymer drug eluting stents, and biodegradable polymer drug eluting stents for coronary artery disease: mixed treatment comparison meta-analysis显示文摘 | Bangalore S Toklu B Amoroso N | 2013 | BMI2013，347，： | 1 |
| 15 | Gemcitabine plus celeeoxib(GECO)in advanced pancreatic cancer:a phase Ⅱ trial显示文摘 | Ferrari V Valcamonico F Amoroso V | 2006 | Cancer Chemother Pharmacol2006，57，： | 1 |
| 16 | Surprisingly small HONO emissions from snow surfaces at Browning Pass, Antarctica 显示文摘 | Beine H J Amoroso A Domine F | 2006 | Atmos Chem Phys2006，6，： | 1 |
| 17 | Asymmetric synthesis of arylpropionic acids and aryloxy acids by using lactamides as chiral auxiliaries 显示文摘 | Ammazzalorso A Amoroso R Bettoni G | 2006 | Eur J Org Chem2006，18，： | 1 |
| 18 | Pathophysiology of vascular endothelium and circulation platelets:implications for coronary revascularization and treatment显示文摘 | Amoroso G van Veldhuisen DJ Tio RA | 2001 | Int J Cardiol2001，79，： | 1 |
| 19 | Identification of a new locus for medullary cystic disease,on chromosome 16pl2显示文摘 | Scolari F Puzzer D Amoroso A | 1999 | Am J Hum Genet1999，64，： | 1 |
| 20 | Decision Procedures for Surjectivity and Injectivity of Parallel Maps for Tessellation Structures显示文摘 | AMOROSO S PATTY | 1972 | Computer System Sci1972，，6： | 1 |
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