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| 1 | 玻璃体内注射贝伐单抗对DME患者视力、黄斑中心厚度和眼血流的影响(英文)显示文摘目的:探讨玻璃体内注射贝伐单抗对伴有黄斑水肿的糖尿病患者眼血流参数的影响。方法:患者21例21眼,伴有弥漫性糖尿病性黄斑水肿(diabeticmacular edema,DME),黄斑中心厚度(central macularthickness,CMT)>320μm,无缺血性黄斑水肿或其他血管性视网膜疾病。患者术前以及注射1.25mg/0.05mL贝伐单抗1d,4wk后接受三种眼科检查:视力(visual acuity,VA)检测、光学相干断层扫描(optical coherence tomography,OCT)测量CMT以及采用超声成像测量眼动脉(ophthalmicartery,OA)、视网膜中央动脉(central retinal artery,CRA)、鼻侧睫状后动脉(nasal posterior ciliary artery,NPCA)以及颞侧睫状后动脉(temporal posterior ciliary artery,TPCA)中的收缩期峰值血流速度(peak systolic velocities,PSV)和舒张末期血流速度(end-diastolic velocities,EDV)。阻力指数(resistive indices,RI)由软件自动计算,注射前与注射后1d的血流速度进行了比较。患者术前和注射后4wk的VA和CMT值进行了比较。结果:注射前平均最佳矫正视力(best-corrected visual acuity,BCVA)为0.88±0.21logMAR,注射后为0.54±0.19logMAR(P<0.01)。平均CMT由注射前440.57±54.58μm下降至250.33±31.12μm(-190.24±36.00μm)。PSV、EDV和RI的变化并不显著。结论:贝伐单抗注射后视力显着改善,CMT降低,而PSV、EDV和RI在OA、CRA、TPCA和NPCA中没有显著变化。玻璃体内注射贝伐单抗注射液能改善VA和CMT,但对于糖尿病患者的OA、CRA、TPCA和NPCA的血流速度没有影响。 | Mehmet Demir Alper Ozel Burcu Dirim Erhan Ozdal Efe Can | 2013 | 国际眼科杂志2013，13，3： | 2 |
| 2 | Computing timing jitter from phase noise spectra for oscillators and phase-locked loops with white and 1/f noise显示文摘 | Alper Demir | 2006 | IEEE Transactions on Ciruits and Systems-I: Regular Papers2006，53，9： | 1 |
| 3 | Phase noise in oscillators: unifying theory and numeri- cal methods for characterization 显示文摘 | Alper Demir Amit Mehrotra Jaijeet Roychowdhury | 2000 | IEEE Trans on Circuits and Systems I: Fundamental Theory and Ap- plications2000，47，5： | 1 |
| 4 | Clitoris metastasis from a retroperitoneal leiomyosarcoma: A case report显示文摘Leiomyosarcoma is a rare form of cancer commonly found in the retroperitoneum, uterus, stomach, small intestine and vascular tissue. Surgery with a wide margin of resection is the most effective treatment. Nevertheless, metastasis is common and generally occurs within the first 3 years. The liver and lungs are the most common sites of metastasis in leiomyosarcoma. Other sites of metastasis include bone, spleen, soft tissues and brain. Metastatic tumours of the clitoris are extremely rare. As cited in the literature, the most common cancers that metastasize to the clitoris are breast, bladder, renal and gastric. Here, we report a case of a clitoral mass in a 64-year-old woman who received an operation for retroperitoneal leiomyosarcoma 4 years prior. Mass resection was performed. The pathological diagnosis was a leiomyosarcoma metastasis. The patient also presented with brain and lung metastases at the time of the clitoral metastasis. This is the first case of clitoral and brain metastases originating from a retroperitoneal leiomyosarcoma. | Suna Cokmert Lutfiye Demir Murat Akyol Ibrahim Vedat Bayoglu Alper Can Ilkay Tugba Unek Filiz Aka Bolat | 2014 | World Journal of Clinical Oncology2014，5，1： | 1 |
| 5 | Phase noise in oscillators: a unifying theory and numerical methods for characterization 显示文摘 | Alper Demir Amit Mehrotra Jaijeet Roychowdhu- ry | 2000 | IEEE Transactions on Circuits and Systems-It Fundamen- tal Theory and Applications2000，47，5： | 1 |
| 6 | Phase noise in oscillators:Unifying theory and numerical methods for characterization显示文摘 | Alper Demir Amit Mehrotra Jaijeet Roychowdhury | 2000 | IEEE Trans on Circuits and Systems I:Fundamental Theory and Applications2000，47，5： | 1 |
| 7 | Phase noise in oscillators : A unifying theory and numerical methods for characterization显示文摘 | Alper Demir Amit Mehrotra Jaijeet Roychowdhury | 2000 | IEEE Transcations on Circuits and Systems-Ⅰ : Fundamental Theory and Applications2000，47，5： | 1 |
| 8 | Computing timing jitter from phase noise spectra for oscillators and phase-locked loops with white and 1/f noise 显示文摘 | Alper Demir | 2006 | IEEE Transcations on Circuits and Systems-Ⅰ: Regular Papers2006，53，9： | 1 |
| 9 | Retinal nerve fiber layer and ganglion cell-inner plexiform layer thickness in children with obesity显示文摘AIM:To evaluate retinal nerve fiber layer(RNFL)thickness analysis of peripapillary optic nerve head(PONH) and macula as well as ganglion cell-inner plexiform layer(GCIPL) thickness in obese children.· METHODS:Eighty-five children with obesity and 30 controls were included in the study.The thicknesses of the PONH and macula of each subject's right eye were measured by high-resolution spectral-domain optic coherence tomography(OCT).· RESULTS:The RNFL thicknesses of central macular and PONH were similar between the groups(all P >0.05).The GCIPL thickness was also similar between the groups.However,the RNFL thickness of temporal outer macula were 261.7±13.7 and 268.9±14.3 μm for the obesity and the control group,respectively(P =0.034).· CONCLUSION:Obesity may cause a reduction in temporal outer macular RNFL thickness. | Selim Demir Samet ozer Sait Alim Alper Günes Hüseyin Ortak Resul Yilmaz | 2016 | International Journal of Ophthalmology(English edition)2016，9，3： | 1 |
| 10 | Phase Noise in Oscillators:A Unifying Theory and Numerical Methods for Charac- terization显示文摘 | Alper Demir Amit Mehrotra Jaijeet Roychowdhury | 2000 | IEEE Transactions on Circuits and Systems--I : Fundamental Theory and Applications2000，47，5： | 1 |
| 11 | Effects of cardiac valve dysfunction on perioperative management of liver transplantation显示文摘 | Alper I Ulukaya S Demir F | | 0，，05： | 1 |
| 12 | Uncritical Receivers of Historical Myths: A Grim Picture From Turkish High Schoolers显示文摘 | Muhammet Avarogullarl Mehmet Alper Demir | 2015 | US-China Education Review(B)2015，5，4： | 0 |
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