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| 1 | Mammary gland growth and vascularity at parturition and during lactation in primiparous ewes fed differing levels of selenium and nutritional plane during gestation显示文摘Background: Objectives were to examine the effects of selenium(Se) supply and maternal nutritional plane during gestation on mammary gland growth, cellular proliferation, and vascularity at parturition and d 20 of lactation. Rambouillet primiparous ewes(n = 84) were allocated to treatments in a 2 x 3 factorial. Factors were dietary Se(adequate Se [ASe, 11.5 μg/kg BW] or high Se [HSe, 77.0 μg/kg BW]) and nutritional plane(60% [RES], 100% [CON], or 140% [EXC]). At parturition, lambs were removed and 42 ewes(7/treatment) were necropsied. Remaining ewes were fed a common diet meeting requirements for lactation and mechanically milked twice daily until necropsy on d 20. At both necropsy periods, mammary glands were dissected and tissues harvested. Samples were analyzed for RNA, DNA, and protein content, cell proliferation, and vascularity. Where interactions were present(P ≤ 0.05), least squares means from the highest-order interaction are presented. Results: Final body weight of ewes was least(P ≤ 0.002) in RES, intermediate for CON, and greatest for EXC, regardless of stage of the ewe at necropsy(parturition or d 20 of lactation). In ewes necropsied at parturition, mammary glands were heavier(P = 0.02) in EXC compared to RES, with CON intermediate. Concentration of RNA(mg/g) was decreased(P = 0.01) in EXC compared to CON at parturition. There was a tendency(P = 0.07) for a Se by nutrition interaction in percentage of cells proliferating where ASe-EXC ewes had greater(P ≤ 0.02) number of proliferating cells then all other treatments. Mammary vascular area tended(P = 0.08) to be affected by a Se by nutrition interaction where ASe-CON had less(P = 0.007) vascular area than HSe-CON ewes. In ewes necropsied at d 20 of lactation, the number of alveoli per area was decreased(P ≤ 0.05) in RES compared to CON and EXC-fed ewes. Conclusions: Results of this study indicate that proper maternal nutritional plane during gestation is important for mammary gland development, even out to d 20 of lactation. | Tammi L Neville Allison M Meyer Arshi Reyaz Pawel B Borowicz Dale A Redmer Lawrence P Reynolds Joel S Caton Kimberly A Vonnahme | 2013 | Journal of Animal Science and Biotechnology2013，4，4： | 3 |
| 2 | Changes in enzymeactivities and soil microbial community composition along carbonand nutrient gradients at the Franz Josef chronosequence,NewZealand显示文摘 | ALLISON V J CONDRON L M PELTZER D A | 2007 | Soil Biological and Biochemistry2007，39，7： | 1 |
| 3 | Valuable patents 显示文摘 | Allison J R Lemley M A Moore K A | 2004 | Georgetown Law Journal2004，92，3： | 1 |
| 4 | Mitral and aortic annular calcification are highly associated with systemic calcified atherosclerosis 显示文摘 | ALLISON M A CHEUNG P CRIQUI M H | 2006 | Circulation2006，113，6： | 1 |
| 5 | Heart mitochondria contain functional ATP-dependent K^+ channels 显示文摘 | Zsombor L James A S Allison W M | 2003 | J Mo Cell Cardiol2003，35，11： | 1 |
| 6 | Estrogen therapy and coronaryartry calcification显示文摘 | Manson J E Allison M A Rossouw J E | 2007 | N Engl J Med2007，356，： | 1 |
| 7 | Valuable patents显示文摘 | Allison J R Lemley M A Moore K A | 2004 | Georgetown Law Journal2004，92，： | 1 |
| 8 | Transport and transformation of dissolved and particulate materials on conti- nental margins influenced by major rivers: benthic boundary layer and seabed processes 显示文摘 | Mekee B A Aller R C Allison M A | 2004 | Continental Shelf Research2004，24，78： | 1 |
| 9 | Pulsed dye laser treatment of bum scars: alleviation or iiTitation显示文摘 | Allison K P Kiernan M N Waters R A | 2003 | ? Burns2003，29，： | 1 |
| 10 | Influence of cranberry juice on attachment of Escherichia coli to glass显示文摘 | Allison D G Cronin M A Hawker J | 2000 | Basic Microbiol2000，40，： | 1 |
| 11 | Behavioural responses of piglets to castration : the effect of piglet age 显示文摘 | Allison A T Daniel M W Martin L | 2001 | AppliedAnimal Behaviour Science2001，73，1： | 1 |
| 12 | Patterns in nutrient availability and plant diversity of temperate north America wetlands显示文摘 | BEDFORD L B WALBRIDGE M R ALLISON A | 1999 | Ecology1999，80，7： | 1 |
| 13 | Degradation of the selective herbicide 2,2-dichloropro-pionate(dalapon)by a soil bacterium显示文摘 | Berry E K M Allison N Skinner A J | 1979 | Journal of General Microbiology1979，110，1： | 1 |
| 14 | Rapid export of riverine-and shelf-derived organic matter into the Mississippi Can- yon显示文摘 | BIANCHI T S ALLISON M A CANUEL E A | 2006 | EOS American Geophysical Union2006，87，： | 1 |
| 15 | Evaluation of nu- tritional support in acute pancreatitis显示文摘 | LOBO D N MEMON M A ALLISON S P | 2000 | Hr J Surg2000，87，6： | 1 |
| 16 | Review of signal processing in genetics显示文摘 | Berryman M J Allison A | 2005 | Fluctuation and Noise Letters2005，5，4： | 1 |
| 17 | The epidemi- ology of subclavian stenosis and its association with markers of subclinical atherosclerosis: the Multi-Ethnic Study of Atherosclerosis (MESA) 显示文摘 | Aboyans V Kamineni A Allison M A | 2010 | Atherosclerosis2010，211，1： | 1 |
| 18 | Hypoth-alamic regulation of cortical bone mass:opposing activity of Y2 re-ceptor and leptin pathway显示文摘 | BALDOCK P A ALLISON S MCDONALD M M | | 0，，10： | 1 |
| 19 | Diannexin treatment decreases ischemia-reperfusion injury at the endothelial cell level of the microvascular bed in muscle flaps 显示文摘 | Molski M Groth A Allison A C | 2009 | Ann Plast Surg2009，63，5： | 1 |
| 20 | Glomerular filtration rate and n-terminal pro-brain natriuretic peptide as predictors of cardiovascular mortality in vascular patients显示文摘 | SHADMAN R ALLISON M A CRIQUI M H | 2007 | J Am Coll Cardiol2007，49，： | 1 |
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