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| 1 | Sperm DNA fragmentation, recurrent implantation failure and recurrent miscarriage显示文摘证据正在增加精子 DNA 的正直可能也与培植失败和周期性的流产(RM ) 有关。调查这,在有在 vitro 授精,与 RM 诊断的 16 个女人和七位最近的父亲(控制) 列在后面的周期性的培植失败(RIF ) 的 35 个女人的搭挡的精子 DNA 破碎被检验。精子由测试和终端 deoxynucleotidyl transferase dUTP 刻痕结束标记的精子染色质分散(SCD )(TUNEL ) 是检验密度前和密度以后的 centrifugation 试金。在在三之间的搭挡或精子集中,活动性或形态学组织的任何一个的年龄没有重要差别。而且,在 DNA 破碎由也测量了的精子没有明显的差别测试。不管多么虽然平均在所有的精子 DNA 破碎组织当由 SCD 测试测量了时,在准备精子是统计上更低的,这没从 TUNEL 试金与结果被看见。这些结果不支持精子 DNA 破碎是 RIF 或 RM 的一个重要原因的假设,否则测试的那精子 DNA 正直在如此的病人有价值。它也在从精子 DNA 破碎测试解释数据加亮测试方法论和精子准备方法之间的重要差别。 | Carol Coughlan Helen Clarke Rachel Cutting Jane Saxton Sarah Waite William Ledger Tinchiu Li Allan A Pacey | 2015 | Asian Journal of Andrology2015，17，4： | 17 |
| 2 | 【特刊综述】性激素与糖代谢显示文摘在患有代谢综合征和2型糖尿病的男性中睾酮水平较低,而睾酮水平也可预示这些不利的代谢状态的出现。身体构成(或称BMI,腰围)是这种关系的重要中介。性激素结合球蛋白也与胰岛素抵抗和2型糖尿病负相关,但是有关雌激素的数据是不一致的。包括克兰费尔特综合征以及治疗晚期前列腺癌的雄激素剥夺疗法在内的雄激素缺乏临床模型确认了雄激素和血糖状态的关联。对胰岛素/血糖环境的实验操作和对内源性睾丸功能的抑制提示了雄激素和胰岛素敏感性的关系是双向的。在没有糖尿病的男性中,雄激素疗法不能区分到底是胰岛素抵抗的效果还是脂肪量的效果,特别是内脏型肥胖。与之类似的是,几个小规模的临床研究验证了外源性睾酮在治疗患有2型糖尿病的男性中的效果,但是在排除了身体构成的影响后,雄激素在减轻胰岛素抵抗中的作用仍是不确定的。 | Carolyn A Allan | 2014 | Asian Journal of Andrology2014，16，2： | 8 |
| 3 | Early combined immunosuppression or conventional management in patients with newly diagnosed Crohn’s disease: an open randomised trial显示文摘 | Geert D’Haens Filip Baert Gert van Assche Philip Caenepeel Philippe Vergauwe Hans Tuynman Martine De Vos Sander van Deventer Larry Stitt Allan Donner Severine Vermeire Frank J Van De Mierop Jean-Charles R Coche Janneke van der Woude Thomas Ochsenkühn Ad A | 2008 | The Lancet2008，，9613： | 5 |
| 4 | Incremental value of magnetic resonance neurography of Lumbosacral plexus over non-contributory lumbar spine magnetic resonance imaging in radiculopathy: A prospective study显示文摘AIM: To test the incremental value of 3T magnetic resonance neurography(MRN) in a series of unilateral radiculopathy patients with non-contributory magnetic resonance imaging(MRI).METHODS: Ten subjects(3 men,7 women; mean age54 year and range 22-74 year) with unilateral lumbar radiculopathy and with previous non-contributory lumbar spine MRI underwent lumbosacral(LS) plexus MRN over a period of one year. Lumbar spine MRI performed as part of the MRN LS protocol as well as bilateral L4-S1 nerves,sciatic,femoral and lateral femoral cutaneous nerves were evaluated in each subject for neuropathy findings on both anatomic(nerve signal,course and caliber alterations) and diffusion tensor imaging(DTI)tensor maps(nerve signal and caliber alterations).Minimum fractional anisotropy(FA) and mean apparent diffusion coeffcient(ADC) of L4-S2 nerve roots,sciatic and femoral nerves were recorded.RESULTS: All anatomic studies and 80% of DTI imaging received a good-excellent imaging quality grading. In a blinded evaluation,all 10 examinations demonstrated neural and/or neuromuscular abnormality corresponding to the site of radiculopathy. A number of contributory neuropathy findings including double crush syndrome were observed. On DTI tensor maps,nerve signal and caliber alterations were more conspicuous. Although individual differences were observed among neuropathic appearing nerve(lower FA and increased ADC) as compared to its contralateral counterpart,there were no significant mean differences on statistical comparison of LS plexus nerves,femoral and sciatic nerves(P > 0.05).CONCLUSION: MRN of LS plexus is useful modality for the evaluation of patients with non-contributory MRI of lumbar spine as it can incrementally delineate the etiology and provide direct objective and non-invasive evidence of neuromuscular pathology. | Avneesh Chhabra Sahar J Farahani Gaurav K Thawait Vibhor Wadhwa Allan J Belzberg John A Carrino | 2016 | World Journal of Radiology2016，8，1： | 4 |
| 5 | 利用腰围身高比预测有雄激素缺乏症的老年男性体内血清睾酮水平显示文摘老年男性血清睾酮的下降可能部分是由肥胖引起的,但是,还不能确定哪些肥胖相关的参数与睾酮水平最密切相关。我们研究过伴有雄激素缺乏症但健康状况良好的老年男性的年龄、肥胖和睾酮水平的关系。本研究中,我们从社区中募集了54岁以上无痛症或其他严重疾病的非吸烟男性做横向研究分析,测定身高,体重和腰围,并计算体质指数(BMI)和腰围身高比(WHt)。收集两个早上的血液样本,测量总睾酮,性激素结合球蛋白和促黄体激素。计算游离睾酮(cFT)。并对上述指标与肥胖参数之间的关系进行多元线性凹归分析。207名54-86岁之间的男性参与了此次研究。单因素分析结果表明腰围身高比与睾酮和游离睾酮的相关性明显高于体重和腰吲或体质指数。另外,对总睾酮和游离睾酮来说,体重和腰围以及身高都有重要意义(所有的P均小于0.05),身高值中加入体重和腰围值后,导致体重和腰用以及身高的回归系数都增加了,其中腰围呈负相关,身高呈正相关。总之,腰围身高比是预测健康但有雄激素缺乏症的老年男性的睾酮和游离睾酮最好的体质指标。 | Carolyn A Allan Roger E Peverill Boyd JG Strauss Elise A Forbes Robert I McLachlan | 2011 | Asian Journal of Andrology2011，13，3： | 3 |
| 6 | Aedes albopictus (Diptera: Culicidae) oviposition response to organic infusions from common flora of suburban Florida显示文摘 | Obenauer P J Allan S A Kaufman P E | 2010 | Journal of Vector Ecology2010，，2： | 2 |
| 7 | A high performance satellite data modem using real-time digital signal processing techniques显示文摘 | Allan R D Bramwell J R Saunders D A | 1988 | J IERE1988，58，3： | 2 |
| 8 | Osteopontin overexpression in breast cancer:knowledge gained and possible implications for clinical management显示文摘 | TUCK AB CHAMBERS AF ALLAN AL | 2007 | J Cell Biochem2007，102，4： | 1 |
| 9 | Enzymes as silage additives for silage quality, digestion, digestibility and performance in growing cattle显示文摘 | Jacobs J L Mc Allan A B | 1991 | Grass and Forage Science1991，46，1： | 1 |
| 10 | 2001 technology roadmap for semiconductors显示文摘 | Allan A Edenfeld D Joyner J Y W H | 2002 | Computer2002，35，1： | 1 |
| 11 | Virtual water: The water, food, and trade nexus useful concept or misleading metaphor显示文摘 | Allan J A | 2003 | Water International2003，28，1： | 1 |
| 12 | A phase Ⅱ study of liposomal lurtotecan (OSI-211) in patients with topotecan resistant ovarian cancer显示文摘 | Michael VS Franco M Allan A | 2004 | Gynecol Oncol2004，93，1： | 1 |
| 13 | An ELISA for the detection of Bacillus subtilis L-form bacteria confirms their symbiosis in strawberry显示文摘 | FERGUSON C M J BOOTHL N A ALLAN E J | 2000 | Lett in Appl Microbiol2000，31，： | 1 |
| 14 | 查看详情显示文摘 | Allan C R Hadwiger L A | | 0，，： | 1 |
| 15 | New Developments in the Marine Nitrogen Cyc1e显示文摘 | Brandes Jay A Devol Allan H Deutsch Curtis | 2007 | Chemical Reviews2007，107，： | 1 |
| 16 | Autonomic function is impaired in elderly stroke survivors 显示文摘 | McLaren A Kerr S Allan L | 2005 | Stroke2005，36，5： | 1 |
| 17 | Demonstration of a shell-core structure in layered cadmium selenide-zinc selenide small particles by x-ray photoelectron and Auger spectroscopies 显示文摘 | HOENER C F ALLAN K A BARD A J | 1992 | J Phys Chem1992，96，： | 1 |
| 18 | Simultaneous demodulation technique for a multiplexed fiber Fizeau interferometer and fiber Bragg grating sensor system显示文摘 | ALLAN C W PAUL A C PENG G D | 2006 | Opt Lett2006，31，1： | 1 |
| 19 | 8-GHz Static Frequency Divider in AlInAs/InGaAs HBT Technology显示文摘 | Fields Charles H Stephen Thomas III Shi Binqiang Young Kim Boegeman Mary Montes Rosanna Martinez Kramer Allan R and Meena Madhav A Low-Power 72 | 2001 | IEEE JOURNAL OF SOLID-STATE CIRCUITS2001，36，： | 1 |
| 20 | Beta (3) integrin expression increases breast carcinoma cell responsiveness to the malignancy enhancing effects of osteopontin显示文摘 | Furger K A Allan A L Wilson S M Hota C Vantyghem S A Postenka C O | 2003 | Mol Cancer Res2003，1，： | 1 |
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