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4篇 您的检索式:作者名="Alla Singh"
    题名 作者 年代 出处 被引量
1An unsolved conundrum: the ideal follow-up strategy after curative surgery for colorectal cancer显示文摘Piriyah Sinclair Anjana Singh Amjid A. Riaz Alla Amin 2012Gastrointestinal Endoscopy2012,,5:2
2An unsolved conundrum: the ideal follow-up strategy after curative surgery for colorectal cancer显示文摘Piriyah Sinclair Anjana Singh Amjid A. Riaz Alla Amin 2012Gastrointestinal Endoscopy2012,,5:1
3Surveying the genomic landscape of silage-quality traits in maize(Zea mays L.)显示文摘Despite the longstanding importance of silage as a critical feed source for ruminants,its quality improvement has been largely overlooked.Although numerous quantitative trait loci(QTL)and genes affecting silage quality in maize have been reported,only a few have been effectively incorporated into breeding programs.Addressing this gap,the present study undertook a comprehensive meta-QTL(MQTL)analysis involving 523 QTL associated with silage-quality traits collected from 14 published studies.Of the 523 QTL,405 were projected onto a consensus map comprising 62,424 genetic markers,resulting in the identification of 60 MQTL and eight singletons.The average confidence interval(CI)of the MQTL was 3.9-fold smaller than that of the source QTL.Nine of the 60 identified MQTL were classified as breeder’s MQTL owing to their small CIs,involvement of more QTL,and large contribution to phenotypic variation.One-third of the MQTL co-localized with DNA marker-trait associations identified in previous genomewide association mapping studies.A set of 78 high-confidence candidate genes influencing silage quality were identified in the MQTL regions.These genes and associated markers may advance marker-assisted breeding for maize silage quality.Jatin Sharma Shubham Sharma Krishna Sai Karnatam Om Prakash Raigar Chayanika Lahkar Dinesh Kumar Saini Sushil Kumar Alla Singh Abhijit Kumar Das Priti Sharma Ramesh Kumar 2023The Crop Journal2023,11,6:0
4Meta-QTL analysis for mining of candidate genes and constitutive gene network development for fungal disease resistance in maize(Zea mays L.)显示文摘The development of resistant maize cultivars is the most effective and sustainable approach to combat fungal diseases.Over the last three decades,many quantitative trait loci(QTL)mapping studies reported numerous QTL for fungal disease resistance(FDR)in maize.However,different genetic backgrounds of germplasm and differing QTL analysis algorithms limit the use of identified QTL for comparative studies.The meta-QTL(MQTL)analysis is the meta-analysis of multiple QTL experiments,which entails broader allelic coverage and helps in the combined analysis of diverse QTL mapping studies revealing common genomic regions for target traits.In the present study,128(33.59%)out of 381 reported QTL(from 82 studies)for FDR could be projected on the maize genome through MQTL analysis.It revealed 38 MQTL for FDR(12 diseases)on all chromosomes except chromosome 10.Five MQTL namely 1_4,2_4,3_2,3_4,and 5_4 were linked with multiple FDR.Total of 1910 candidate genes were identified for all the MQTL regions,with protein kinase gene families,TFs,pathogenesis-related,and disease-responsive proteins directly or indirectly associated with FDR.The comparison of physical positions of marker-traits association(MTAs)from genome-wide association studies with genes underlying MQTL interval verified the presence of QTL/candidate genes for particular diseases.The linked markers to MQTL and putative candidate genes underlying identified MQTL can be further validated in the germplasm through marker screening and expression studies.The study also attempted to unravel the underlying mechanism for FDR resistance by analyzing the constitutive gene network,which will be a useful resource to understand the molecular mechanism of defense-response of a particular disease and multiple FDR in maize.Mamta Gupta Mukesh Choudhary Alla Singh Seema Sheoran Deepak Singla Sujay Rakshit 2023The Crop Journal2023,11,2:0
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