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| 1 | Accuracy of urea breath test in Helicobacter pylori infection: Meta-analysis显示文摘AIM: To quantitatively summarize and appraise the available evidence of urea breath test(UBT) use to diagnose Helicobacter pylori(H. pylori) infection in patients with dyspepsia and provide pooled diagnostic accuracy measures.METHODS: We searched MEDLINE, EMBASE, Cochrane library and other databases for studies addressing the value of UBT in the diagnosis of H. pylori infection. We included cross-sectional studies that evaluated the diagnostic accuracy of UBT in adult patients with dyspeptic symptoms. Risk of bias was assessed using QUADAS(Quality Assessment of Diagnostic Accuracy Studies)-2 tool. Diagnostic accuracy measures were pooled using the random-effects model. Subgroup analysis was conducted by UBT type(13C vs 14C) and by measurement technique(Infrared spectrometry vs Isotope Ratio Mass Spectrometry).RESULTS: Out of 1380 studies identified, only 23 met the eligibility criteria. Fourteen studies(61%) evaluated 13 C UBT and 9 studies(39%) evaluated 14 C UBT. There was significant variation in the type of reference standard tests used across studies.Pooled sensitivity was 0.96(95%CI: 0.95-0.97) andpooled specificity was 0.93(95%CI: 0.91-0.94). Likelihood ratio for a positive test was 12 and for a negative test was 0.05 with an area under thecurve of 0.985. Meta-analyses were associated with a significant statistical heterogeneity that remained unexplained after subgroup analysis. The included studies had a moderate risk of bias.CONCLUSION: UBT has high diagnostic accuracy for detecting H. pylori infection in patients with dyspepsia. The reliability of diagnostic meta-analytic estimates however is limited by significant heterogeneity. | Mazen Ferwana Imad Abdulmajeed Ali Alhajiahmed Wedad Madani Belal Firwana Rim Hasan Osama Altayar Paul J Limburg Mohammad Hassan Murad Bandar Knawy | 2015 | World Journal of Gastroenterology2015，21，4： | 45 |
| 2 | 真空-堆载预压作用下软土蠕变特性试验研究显示文摘采用改进的、可施加负压的三轴仪开展了真空预压、堆载预压以及真空-堆载联合预压作用下软土的固结蠕变试验,描述了加载率、应力比和时间等对软土蠕变特性的影响,分析了轴向应变(率)、体积应变(率)及偏应变(率)与应力比和时间之间的关系。结果表明:轴向应变率和体积应变率与时间的对数关系并非线性,但经过若干天以后可近似认为是线性关系;在不同应力比n下,体应变与时间的关系可用双曲线方程来表示;偏应变、偏应变率与时间的关系符合双曲线方程,通过温州软黏土样的蠕变试验结果验证了其有效性。 | 刘汉龙 扈胜霞 Ali Hassan | 2008 | 岩土力学2008，29，1： | 21 |
| 3 | Energy-efficient Virtual Machine Allocation Technique Using Flower Pollination Algorithm in Cloud Datacenter:A Panacea to Green Computing显示文摘Cloud computing has attracted significant interest due to the increasing service demands from organizations offloading computationally intensive tasks to datacenters.Meanwhile,datacenter infrastructure comprises hardware resources that consume high amount of energy and give out carbon emissions at hazardous levels.In cloud datacenter,Virtual Machines(VMs)need to be allocated on various Physical Machines(PMs)in order to minimize resource wastage and increase energy efficiency.Resource allocation problem is NP-hard.Hence finding an exact solution is complicated especially for large-scale datacenters.In this con text,this paper proposes an Energy-oriented Flower Pollination Algorithm(E-FPA)for VM allocation in cloud datacenter environments.A system framework for the scheme was developed to enable energy-oriented allocation of various VMs on a PM.The allocation uses a strategy called Dynamic Switching Probability(DSP).The framework finds a near optimal solution quickly and balances the exploration of the global search and exploitation of the local search.It considers a processor,storage,and memory constraints of a PM while prioritizing energy-oriented allocation for a set of VMs.Simulations performed on MultiRecCloudSim utilizing planet workload show that the E-FPA outperforms the Genetic Algorithm for Power-Aware(GAPA)by 21.8%,Order of Exchange Migration(OEM)ant colony system by 21.5%,and First Fit Decreasing(FFD)by 24.9%.Therefore,E-FPA significantly improves datacenter performance and thus,enhances environmental sustainability. | Mohammed Joda Usman Abdul Samad Ismail Hassan Chizari Gaddafi Abdul-Salaam Ali Muhammad Usman Abdulsalam Yau Gital Omprakash Kaiwartya Ahmed Aliyu | 2019 | Journal of Bionic Engineering2019，16，2： | 13 |
| 4 | Critical role of SDF-1/CXCR4 signaling pathway in stem cell homing in the deafened rat cochlea after acoustic trauma显示文摘Previous animal studies have shown that stromal cell-derived factor-1(SDF-1)/CXC chemokine receptor-4(CXCR4) signaling pathway plays an important role in the targeted migration of bone marrow-derived mesenchymal stem cells(BMSCs) to the injured area. In the present study, we aimed to investigate the potential role of chemotactic SDF-1/CXCR4 signaling pathway in the homing of transplanted BMSCs to the injured cochlea after noise-induced hearing loss(NIHL) in a rat model. White noise exposure(110 d B) paradigm was used for hearing loss induction in male rats for 6 hours in 5 days. Distortion-product otoacoustic emission(DPOAE) responses were recorded before the experiment and post noise exposure. Hoechst 33342-labeled BMSCs and CXCR4 antagonist(AMD3100)-treated BMSCs were injected into the rat cochlea through the round window. SDF-1 protein expression in the cochlear tissue was assayed using western blot assay. The number of labeled BMSCs reaching the endolymph was determined after 24 hours. SDF-1 was significantly increased in the cochlear tissue of rats in the noise exposure group than in the control group. The number of Hoechst 33342-labeled BMSCs reaching the endolymph of the cochlea was significantly smaller in the AMD3100-treated BMSCs group than in the normal BMSCs group. Our present findings suggest that the SDF-1/CXCR4 signaling pathway has a critical role in BMSCs migration to the injured cochlea in a rat model of noise-induced hearing loss. | Ali Asghar Peyvandi Navid Ahmady Roozbahany Hassan Peyvandi Hojjat-Allah Abbaszadeh Niloofar Majdinasab Mohammad Faridan Somayeh Niknazar | 2018 | Neural Regeneration Research2018，13，1： | 11 |
| 5 | 脂蛋白相关磷脂酶A2基因rs13218408与急性脑梗死相关因素的研究显示文摘目的研究急性脑梗死患者脂蛋白相关磷脂酶A2(1ipoproteinassociatedphospholipaseA2,Lp-PLA2)基因rs13218408多态性与Lp-PLA2、同型半胱氨酸(homocysteine,HCY)、C反应蛋白(cprotein,CRP)水平的变化及影响因素的关系。方法将2016年4月-2017年12月徐州医科大学收治的102例符合筛选标准的急性脑梗死患者根据美国国立卫生院卒中量表(nationalinstitutesofhealthstrokescal,NIHSS)评价神经功能缺损程度,分为轻度、中重度组。入院后分别化验Lp-PLA2、HCY、CRP、血常规和血生化;采用聚合酶链反应及基因测序技术检测血清Lp-PLA2基因rs13218408多态性。结果急性脑梗死患者中重度组Lp-PLA2、HCY、CRP显著高于轻度组,均差异有统计学意义(P〈0.05)。急性脑梗死患者中重度组血白细胞(whitebloodcells,WBC)、中性粒细胞(neutrophil,NE)、甘油三酯(triglyceride,TG)、低密度脂蛋白(10wdensitylipoprotein,LDL)、脂蛋白[1ipoproteinLp,Lp(a)]、葡萄糖(glueose,Gin)水平明显高于对照组;高密度脂蛋白(highdensitylipoprotein,HDL)低于对照组,均差异有统计学意义(P〈0.05)。脑梗死中重度组患者Lp-PLA2基因rs13218408多态性位点CC基因型频率81.3%,C等位基因频率87.1%,与轻度组比较差异有统计学意义(P〈O.05),且CC纯合子血清Lp-PLA2水平(440.1±92.3)μg/L较T等位基因携带者(CT+TT)(276.5±67.8)μg/L高(P〈0.01)。结论在急性脑梗死患者中Lp-PLA2、HCY、CRP均增高,且中重度患者增高显著,LP-PLA2基因rsl3218408多态性可能是中国苏北地区汉族人群急性脑梗死发病及病情严重程度的影响因素之一。 | Hassan Ahmed Ali Hyderi 赵琪玉 郭秉楠 赵宁军 纵雪梅 胡书群 燕宪亮 许铁 | 2018 | 中国急救复苏与灾害医学杂志2018，13，7： | 11 |
| 6 | 煤炭腐植酸作为土壤改良剂对土壤物理性质和小麦产量的影响显示文摘在巴基斯坦旁遮普的波特瓦地区(33°N,74°E),集约化土壤耕作,土壤侵蚀和低量作物残体的投入是导致土壤结构退化的原因。结构不稳定的土壤很容易受到侵蚀,反过来,土壤侵蚀又会造成作物产量的下降。因此,为了改善土壤的物理性状,在巴基斯坦旁遮普的干旱地区进行了田间试验。试验地点位于大学(拉瓦尔品第PMAS干旱农业大学)研究农场的园区内。2种不同等级(实验室级和商品级)的腐植酸(HA)各分8个水平,施用2年,处理分别为HL_0(对照,不施腐植酸),HL_1 10 kg HA/hm^2,HL_2 20 kg HA/hm^2,HL_3 30 kg HA/hm^2,HL_4 60 kg HA/hm^2,HL_5 90 kg HA/hm^2,HL_6 120 kg HA/hm^2和HL_7 150 kg HA/hm^2,各处理同时配合施用N-P-K(120-90-60 kg/hm^2)。试验期间,检测土壤总有机碳、饱和导水率、团聚体稳定性、容重、土壤含水量和作物产量。试验结果表明,腐植酸能通过影响土壤总有机碳、饱和导水率、团聚体稳定性、容重和土壤含水量等指标来改善土壤的物理性状。2年试验结果均表现为,实验室级的腐植酸比商品级的腐植酸能更好地改善土壤物理性状,从而提高小麦产量。2种不同级别的腐植酸各施用水平与对照相比,差异均显著。在120 kg/hm^2和150 kg/hm^2的腐植酸施用水平下,大多数指标均显示出了相似的结果,因此,从经济角度考虑,120 k g/hm^2的腐植酸用量为最佳施用量。 | Ijaz Ahmad Safdar Ali Khalid Saifullah Khan Fayyazul Hassan Kashif Bashir 何一通 孙志梅 | 2016 | 腐植酸2016，，3： | 10 |
| 7 | Spatio-temporal distribution of malaria vectors(Diptera:Culicidae) across different climatic zones of Iran显示文摘Malaria is a main vector-borne public health problem in Iran.The last studies on Iranian mosquitoes show 31 Anopheles species including different sibling species and genotypes,eight of them are reported to play role in malaria transmission.The objective of this study is to provide a reference for malaria vectors of Iran and to map their spatial and temporal distribution in different climatic zones.Shape files of administrative boundaries and climates of Iran were provided by National Cartographic Center.Data on distribution and seasonal activity of malaria vectors were obtained from different sources and a databank in district level was created in Excel 2003, inserted to the shape files and analyzed by ArcGIS 9.2 to provide the maps.Anopheles culicifacies Giles s.l.,Anopheles dthali Patton,Anopheles fluviatilis James s.L,Anopheles maculipennis Meigen s.L,Anopheles sacharovi Favre,Anopheles stephensi IJston,and Anopheles superpictus Grassi have been introduced as primary and secondary malaria vectors and Anopheles puicherrimus Theobald as a suspected vector in Iran.Temporal distribution of anopheline mosquitoes is restricted to April_December in northern Iran,however mosquitoes can be found during the year in southern region.Spatial distribution of malaria vectors is different based on species,thus six of them(except for Anopheles maculipennis s.l.and Anopheles sacharovi) are reported from endemic malarious area in southern and southeastern areas of Iran.The climate of this part is usually warm and humid,which makes it favorable for mosquito rearing and malaria transmission.Correlation between climate conditions and vector distribution can help to predict the potential range of activity for each species and preparedness for malaria epidemics. | Ahmad Ali Hanafi-Bojd Shahyad Azari-Hamidian Hassan Vatandoost Zabihollah Charrahy | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，6： | 10 |
| 8 | The Role and Function of Ras-association domain family in Cancer:A Review显示文摘Ras gene mutation has been observed in more than 30%of cancers,and 90%of pancreatic,lung and colon cancers.Ras proteins(K-Ras,H-Ras,N-Ras)act as molecular switches which are activated by binding to GTP.They play a role in the cascade of cell process control(proliferation and cell division).In the inactive state,transforming GTP to GDP leads to the activation of GTpase in Ras gene.However,the mutation in Ras leads to the loss of internal GTPase activity and permanent activation of the protein.The activated Ras can promote the cell death or stop cell growth,which are facilitated by Ras-association domain family.Various studies have been conducted to determine the importance of losing RASSF proteins in Rasinduced tumors.This paper examines the role of Ras and RASSF proteins.In general,RASSF proteins can be used as a suitable means for targeting a large group of Ras-induced tumors. | Mohammad Reza Zinatizadeh Seyed Ali Momeni Peyman Kheirandish Zarandi Ghanbar Mahmoodi Chalbatani Hassan Dana Hamid Reza Mirzaei Mohammad Esmaeil Akbari Seyed Rouhollah Miri | 2019 | Genes & Diseases2019，6，4： | 10 |
| 9 | Isolation and efficacy of entomopathogenic fungus(Metarhizium anisopliae)for the control of Aedes albopictus Skuse larvae:suspected dengue vector in Pakistan显示文摘Objective:To isolate the entomopathogenic fungus Metarhixium anisopliae(M.anisopliae) in the local environment,and evaluate its efficacy against the suspected dengue vector Aedes albopictus in Pakistan.Methods:According to the standard procedure,M.anisopliae was isolated from the dead mosquitoes which were collected from the field or dead after the collection.Bioassay was performed to determine its efficacy.Results:The results indicated that M.anisopliae had larvicidal effect with LC,value 1.09×10~5 and LC_(50) value 1.90×10^(13) while it took 45.41 h to kill 50% of tested population.Conclusions:Taking long time to kill 50%population when compare with the synthetic insecticides,is the only drawback for the use of entomopathogenic fungus but these bio-pesticides are safe for the use. | Hazrat Bilal Soaib Ali Hassan Imtinan Akram Khan | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，4： | 8 |
| 10 | Modeling and control for cooperative transport of a slung fluid container using quadrotors显示文摘In this paper, dynamic modeling and control problem for transfer of a sloshing liquid container suspended through rigid massless links from a team of quadrotors are investigated. By the proposed solution, pose of the slung container and fluid sloshing modes are stabilized appropriately. Dynamics of the container-liquid-quadrotors system is modeled by Euler-Lagrange method.Fluid slosh dynamics is included using multi-mass-spring model. According to derived model, a proper control law is designed for a system with three or more quadrotors. Implementing the proposed control law, quadrotors can control pose of the container, directions of the links and liquid sloshing modes simultaneously. Stability of closed loop system of tracking errors and sloshing modes are demonstrated using a theory of singularly perturbed systems and Lyapunov stability theorem. Also, the capability of the proposed feedback control laws in solving a formerly organized transport problem of a liquid filled container has been demonstrated in simulations. Moreover, priority of the proposed control scheme to an existing slung load controller in the literature is demonstrated. | Hassan SAYYAADI Ali SOLTANI | 2018 | Chinese Journal of Aeronautics2018，31，2： | 7 |
| 11 | Preyssler-type heteropoly acid:A new,mild and efficient catalyst for protection of carbonyl compounds显示文摘Preyssler 类型 heteropoly,酸与 1,3 丙烷 dithiol 为许多羰基混合物的保护作为新、温和、有效的催化剂被介绍。 | Mohammad Rahimizadeh Tahmineh Bazazan Ali Shiri Mehdi Bakavoli Hassan Hassani | 2011 | Chinese Chemical Letters2011，22，4： | 7 |
| 12 | 化学修饰多壁碳纳米管制备碳糊电极用于伏安法测定药物和尿液中的异丙肾上腺素(英文)显示文摘A carbon paste electrode with added multiwall carbon nanotubes chemically modified with N-(3,4-dihydroxyphenethyl)- 3,5-dinitrobenzamide was used as the electrochemical sensor for the determination of trace amounts of isoprenaline. The modified electrode showed good electrocatalytic activity for the anodic oxidation of isoprenaline, which was due to a substantial decrease in the anodic overpotential. Under the optimum conditions, measurements using square wave voltammetry had a linear range in the range of 0.3 to 125.0 μmol/L of isoprenaline and a detection limit of 0.1 μmol/L. The diffusion coefficient and kinetic parameters were determined using electrochemical methods. The relative standard deviation for seven successive assays of 1.0 and 20.0 μmol/L isoprenaline were 1.9% and 2.4%, respectively.This electrochemical sensor was successfully applied for the determination of isoprenaline in human urine and injection solution samples. | Ali A.ENSAFI Hajar BAHRAMI Hassan KARIMI-MALEH Shadpour MALLAKPOUR | 2012 | 催化学报2012，33，12： | 6 |
| 13 | Characterization of lipid parameters in diabetic and non-diabetic atherosclerotic patients显示文摘背景 &在类脂化合物侧面不安和糖尿病之间的 ObjectiveThe 关系联系了复杂并发症长是兴趣的一个区域。Dyslipidemia 在糖尿病的病人是心血管的病态和死亡的一个有势力预言者。现在的学习的目的是在百和 76 个个人(45-75 年年龄) 参予了的糖尿病、非糖尿病的动脉粥样硬化患者 patients.MethodsFive 调查在老化和类脂化合物侧面之间的关系这研究。在这些之中, 192 正在有糖尿病 mellitus 和动脉粥样硬化的历史。个人们在健康的底上被分类(正常、非糖尿病的动脉粥样硬化,糖尿病的动脉粥样硬化) 并且年龄(45-55 年, 56-65 年,和 66-75 年) 。所有参加者受到象详细历史一样的过程,为 fasting 血糖的生物化学的分析,血红素 A1c,全部的胆固醇(TC ) , triglycerides (TG ) ,低密度的脂蛋白 --(LDL ) ,很低密度的脂蛋白(VLDL ) 和高密度的脂蛋白(HDL ) 。所有这些参数在所有三个年龄组的糖尿病、非糖尿病的动脉粥样硬化患者病人之间被比较。TC/HDL 和 LDL/HDL 也是有的 calculated.ResultsDiabetic 动脉粥样硬化患者个人(男性和女性) 与非糖尿病的动脉粥样硬化患者和正常控制个人相比的 HDL 的 TC, TG, LDL, VLDL 和底层高级。在所有三个年龄组之中,脂蛋白反常被观察比男性在女性更经常。在与年龄相比的糖尿病的动脉粥样硬化患者题目 TC/HDL 和 LDL/HDL 比率有重要增加,性别随两性的年龄的增加匹配非糖尿病的动脉粥样硬化患者和 dyslipidemia 增加的正常 control.ConclusionsDegree。女性是对糖尿病的 dyslipidemia 敏感的更多并且因此有与增加年龄开发动脉粥样硬化的更多的风险。 | Fatima Ali Hassan Jamil Sanam Saiqa Anwar Nadia Wajid | 2015 | Journal of Geriatric Cardiology2015，12，1： | 6 |
| 14 | Emotion processing in Parkinson's disease: a blood oxygenation level-dependent functional magnetic resonance imaging study显示文摘Parkinson's disease is a neurodegenerative disorder caused by loss of dopamine neurons in the substantia nigra pars compacta. Tremor, rigidity, and bradykinesia are the major symptoms of the disease. These motor impairments are often accompanied by affective and emotional dysfunctions which have been largely studied over the last decade. The aim of this study was to investigate emotional processing organization in the brain of patients with Parkinson's disease and to explore whether there are differences between recognition of different types of emotions in Parkinson's disease. We examined 18 patients with Parkinson's disease(8 men, 10 women) with no history of neurological or psychiatric comorbidities. All these patients underwent identical brain blood oxygenation level-dependent functional magnetic resonance imaging for emotion evaluation. Blood oxygenation level-dependent functional magnetic resonance imaging results revealed that the occipito-temporal cortices, insula, orbitofrontal cortex, basal ganglia, and parietal cortex which are involved in emotion processing, were activated during the functional control. Additionally, positive emotions activate larger volumes of the same anatomical entities than neutral and negative emotions. Results also revealed that Parkinson's disease associated with emotional disorders are increasingly recognized as disabling as classic motor symptoms. These findings help clinical physicians to recognize the emotional dysfunction of patients with Parkinson's disease. | Mohammed Benzagmout Sa?d Boujraf Badreeddine Alami Hassane Ali Amadou Halima El Hamdaoui Amine Bennani Mounir Jaafari Ismail Rammouz Mustapha Maaroufi Rabia Magoul Driss Boussaoud | 2019 | Neural Regeneration Research2019，14，4： | 6 |
| 15 | Simultaneous determination of cysteamine and folic acid in pharmaceutical and biological samples using modified multiwall carbon nanotube paste electrode显示文摘一个碳浆糊电极(用户终端设备) 化学上与 multiwall 碳 nanotubes 修改了, ferrocene (FC ) 为 cysteamine (CA ) 和 folic 酸(FA ) 的踪迹数量的同时的决心被用作一个选择电气化学的传感器。这个修改电极为 CA 的阳极的氧化显示出很有效的 electrocatalytic 活动。CA 和 FA 的微分脉搏 voltammograms 的山峰水流在 0.7200 mol/L CA 和 5.0700 mol/L FA 的范围与他们的集中线性地增加了。为 CA 和 FA 的察觉限制分别地是 0.3 mol/L 和 2.0 mol/L。散开系数(D) 和转移系数() CA 也被决定。这些条件是足够的个别地并且同时允许 CA 和 FA 的决心。 | Ali Taherkhani Hassan Karimi-Maleh Ali A.Ensafi Hadi Beitollahi Ahmad Hosseini Mohammad A.Khalilzadeh Hassan Bagheri | 2012 | Chinese Chemical Letters2012，23，2： | 6 |
| 16 | Evaluation of protective effect of cactus pear seed oil(Opuntia ficusincida L. MILL.) against alloxan-induced diabetes in mice显示文摘Objective: To evaluate the in vitro antioxidant power of cactus pear seed oil [Opuntia ficusincida L. MILL.(CPSO)] and its protective effect against chemically induced diabetes mellitus in mice. Methods: The in vitro antioxidant effect of CPSO was evaluated using 2,2-diphenyl-1-picrylhydrazyl(DPPH) scavenging assay. The preventive effect was conducted on Swiss albino mice treated with CPSO(2 m L/kg, per os), before and after a single intraperitoneal alloxan administration(100 mg/kg). Survival rate, body weight and fasting blood glucose were measured and histopathological analysis of pancreas was performed to evaluate alloxaninduced tissue injuries. Results: CPSO exhibited an antioxidant effect in DPPH scavenging assay. Moreover, the administration of CPSO(2 m L/kg) significantly attenuated alloxaninduced death and hyperglycemia(P<0.001) in treated mice. Morphometric study of pancreas revealed that CPSO significantly protected islets of langerhans against alloxan induced-tissue alterations. Conclusions: Based on theses results, CPSO can prevent alloxan-induced-diabetes by quenching free radicals produced by alloxan and inhibiting tissue injuries in pancreatic β-cells. | Berraaouan Ali Ziyyat Abderrahim Mekhfi Hassane Legssyer Abdelkhaleq Aziz Mohammed Bnouham Mohamed | 2015 | Asian Pacific Journal of Tropical Medicine2015，8，7： | 6 |
| 17 | Effect of mucin production on survival in colorectal cancer:A case-control study显示文摘AIM: To investigate the impact of mucin production on prognosis in colorectal cancer, in terms of overall survival (OS) and time to disease progression (TTP) in patients with mucinous compared to those with non-mucinous colorectal cancer (NMCRC), matched for age, gender, and tumor stage.METHODS: Thirty five patients with mucinous colorectal cancer (MCRC) were matched for age, gender, and tumor stage with 35 controls having NMCRC. OS and TTP were compared among 4 groups divided according to mucin content: group A (50%-75% mucin), group B (75%-100% mucin), group C or controls (< 50% mucin). Group D consisted of all patients with tumors having < 75% mucin (controls and groups A together).RESULTS: Median survival in MCRC and NMCRC groups was 46.2 and 112.9 mo, respectively (P = 0.26). OS in groups A and B was 70.1 and 32.8 mo (P = 0.46), and in groups B and D was 32.8 and 70.1 mo, respectively (P = 0.143). TTP in MCRC and NMCRC was 50.17 and 44.77 mo, respectively (P = 0.795). TTP in groups A, B, and D was 70.1, 24.8, and 65.5 mo, respectively. Twenty-eight percent of patients with MCRC had poorly differentiated adenocarcinoma versus 8.6% in NMCRC patients (P = 0.028).CONCLUSION: MCRC is associated with a non-significant decrease in median survival and TTP, particularlywhen mucin content is > 75% of tumor volume. However, it tends to be more poorly differentiated. A larger study matching for stage and grade is needed. | Mirna H Farhat Kassem A Barada Ayman N Tawil Doha M Itani Hassan A Hatoum Ali I Shamseddine | 2008 | World Journal of Gastroenterology2008，14，45： | 6 |
| 18 | Detection and sequencing of plasmid encoded tetracycline resistance determinants(tetA and tetB) from food-borne Bacillus cereus isolates显示文摘Objective:To investigate the detection and sequencing of plasmid encoded tetracycline resistance genes(tet A and tet B) from food-borne and standard strains of Bacillus cereus(B. cereus).Methods:PCR was carried out to detect the tetracycline resistance genes(tet A and tet B) in food-borne B.cereus strains and the amplified products were sequenced.Results:The phenotypic resistance against tetracycline was observed in 39 of the 118 food-borne isolates and two reference strains(MTCC 430 and MTCC 1307) of B.cereus.Among the phenotypically resistant isolates,tet A was detected in 36 food-borne isolates and two reference strains(MTCC 430 and MTCC 1307).whereas,tel B was detected in 12 food-bome isolates and MTCC 1307 strain. Conclusions:A close association was therefore found between phenotypic resistance against tetracycline and presence of tetracycline resistance genes.The tet A and tet B gene fragments were amplified,purified and sequenced.The gene sequences of the isolates studied herein were found similar to tetA and tetB gene sequences of other bacteria available in NCBI.The occurrence of tetA and tetB genes in B.cereus indicate the horizontal transfer of antibiotic resistance determinants from other bacteria into B.cereus.The transfer of these resistant determinants to other potentially pathogenic bacteria may be a matter of great concern. | Mudasir Ali Rather Rabinder Singh Aulakh Jatinder Paul Singh Gill Abdul Qayoom Mir Mir Nadeem Hassan | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，9： | 6 |
| 19 | 方波伏安法测定新型修饰多壁碳纳米管糊电极对肼的电催化氧化(英文)显示文摘The application of p-aminophenol as a suitable mediator, as a sensitive and selective voltammetric sensor for the determination of hydrazine using square wave voltammetric method were described. The modified multiwall carbon nanotubes paste electrode exhibited a good electrocatalytic activity for the oxidation of hydrazine at pH = 7.0. The catalytic oxidation peak currents showed a linear dependence of the peaks current to the hydrazine concentrations in the range of 0.5–175 μmol/L with a correlation coefficient of 0.9975. The detection limit (S/N = 3) was estimated to be 0.3 μmol/L of hydrazine. The relative standard deviations for 0.7 and 5.0 μmol/L hydrazine were 1.7 and 1.1%, respectively. The modified electrode showed good sensitivity and selectivity. The diffusion coefficient (D = 9.5 × 10–4 cm2/s) and the kinetic parameters such as the electron transfer coefficient (α = 0.7) of hydrazine at the surface of the modified electrode were determined using electrochemical approaches. The electrode was successfully applied for the determination of hydrazine in real samples with satisfactory results. | Ali A. ENSAFI Mahsa LOTFI Hassan KARIMI-MALEH | 2012 | 催化学报2012，33，3： | 6 |
| 20 | An exploratory study on the use of enzyme activities as sediment tracers:biochemical fingerprints?显示文摘Little information exists on the potential of soil enzyme activities,which are sensitive to soil properties and management,for the characterization of sediment sources at the catchment scale.The objective of this study is to explore and evaluate enzyme activity as tracer for sediment fingerprinting in the Hiv catchment(55 km^2),Iran.Therefore,four enzymes were measured from 42 different sampling sites,covering three sediment source areas(rangeland/surface erosion,orchard/surface erosion,and streambank erosion),as well as from 12 sediment samples from reservoir check dams (sediment sinks).The results indicate that,based upon backward mode discriminant analysis,βglucosidase and dehydrogenase,allowed more than 95%of the samples to be correctly assigned to their source areas.These enzymes were selected as input data for a mixing-model to determine the relative contribution of the sampled sediment sources.The mean contributions from rangeland, orchard and streambank sources in the study area were estimated as 11.3%,15.1%and 73.7%, respectively.Using geochemical tracers,the mean contribution from rangeland,orchard and streambank sources was estimated as 14.1%,9.5%and 74.8%,respectively.Combined biochemical and geochemical tracers,similar values were obtained(18.7%,10.7%and 70.7%,respectively).Our results indicate that soil enzyme activity allows for a good characterization of sediment sources,and can provide a complementary tool to currently existing sediment fingerprinting approaches.However, the method should be also tested in other regions. | Kazem NOSRATI Gerard GOVERS Hassan AHMADI Forood SHARIFI Mohammad Ali AMOOZEGAR Roel MERCKX Matthias VANMAERCKE | 2011 | International Journal of Sediment Research2011，26，2： | 5 |
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