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| 1 | 急性缺血性卒中静脉阿替普酶溶栓治疗的纳入和排除标准的科学依据美国心脏协会/美国卒中协会对医疗卫生专业人员发布的声明(续前)显示文摘19 颅内出血史
根据最初的 FDA 标签和2013年AHA/ASA指南,颅内出血史是静脉阿替普酶治疗缺血性卒中的一项额外禁忌证或排除标准。最近修订后的标签仅将近期 ICH 列为一项警告,并且在禁忌证中删除了ICH史。与前面讨论的静脉阿替普酶治疗排除标准相似,文献回顾仅在大样本回顾性研究中发现了少量这类病例。缺乏相关数据可能是修订后的FDA 标签不再将 ICH 史作为禁忌证而仅将近期ICH 列为一项警告的原因。在这种情况下,FDA 如何定义“近期”一词尚不清楚。有趣的是,对在静脉阿替普酶治疗前通过 MRI 检测脑微出血( cerebral microbleed, CMBs)存在情况进行的研究可为这个卒中亚组患者提供更多的见解。从病理生理学角度,这种微出血的原因尚不清楚,可能反映再灌注损伤或脑血管自动调节功能破坏。因此,在静脉阿替普酶治疗后出现这些损害可能没有意义或是人为信号。 | Dawn O. Kleindorfer Opeolu M. Adeoye Andrew M. Demchuk Jennifer E. Fugate James C. Grotta Alexander A. Khalessi Elad I. Levy Yuko Y. Palesch Shyam Prabhakaran Gustavo Saposnik Jeffrey L. Saver Eric E. Smith 高圆圆 顾雨铖 徐欣 徐曼曼 张佳慧 李韶雅 冒萧萧 陈歆 徐运 | 2016 | 国际脑血管病杂志2016，24，5： | 98 |
| 2 | A community-derived classification for extant lycophytes and ferns显示文摘发展史长通知了蕨类植物分类。当我们推断进化的树的能力改善了,针对认出生来的组的分类变得逐渐地预兆、稳定。这里,我们为 lycophytes 和蕨纲植物提供一个现代、全面分类,在下面,利用一条基于社区的途径类水平。我们 monophyly 用作主要标准让 taxa,而且目的识别保存两个广泛地被接受的存在 taxa 和界限并且与我们蕨类植物发展史的理解一致。总共,这个分类对待一在 337 个类, 51 个家庭, 14 目,和二个班估计了 11 916 种类。这个分类没在 lycophyte 和蕨纲植物上作为最后的词被打算分类,而是当前的假设的概括陈述,源于最好的可得到的数据并且在问题由熟悉植物的那些大多数塑造了。我们希望它将在蕨类植物上为最近的文学的那些想要的参考用作一个资源发展史和分类,为指导未来调查的一个框架,和推进讲话的刺激。 | Eric Schuettpelz Harald Schneider Alan R. Smith Peter Hovenkamp Jefferson Prado Germinal Rouhan Alexandre Salino Michael Sundue Thafs Elias Almeida Barbara Parris Emily B. Sessa Ashley R. Field Andre Luis de Gasper Carl J. Rothfels Michael D. Windham Marcus Lehnert Benjamin Dauphin Atsushi Ebihara Samuli Lehtonen Pedro Bond Schwartsburd Jordan Metzgar Li-Bing Zhang Li-Yaung Kuo Patrick J. Brownsey Masahiro Kato Marcelo Daniel Arana Francine C. Assis Michael S. Barker David S. Barrington Ho-Ming Chang Yi-Han Chang Yi-Shan Chao Cheng-Wei Chen De-Kui Chen Wen-Liang Chiou Vinicius Antonio de Oliveira Dittrich Yi-Fan Duan Jean-Yves Dubuisson Donald R. Farrar Susan Fawcett Jose Maria Gabriel y Galan Luiz Armando de Araujo Goes-Neto Jason R. Grant Amanda L. Grusz Christopher Haufler Warren Hauk Hai He Sabine Hennequin Regina Yoshie Hirai Layne Huiet Michael Kessler Petra Korall Paulo H. Labiak Anders Larsson Blanca Leen Chun-Xiang Li Fay-Wei Li Melanie Link-Perez Hong-Mei Liu Ngan Thi Lu Esteban I. Meza-Torres Xin-Yuan Miao Robbin Moran Claudine Massi Mynssens Nathalie Nagalingum Benjamin Ollgaard Alison M. Paul Jovani B. de S. Pereira Leon R. Perrie Monica Ponce Tom A. Ranker Christian Schulz Wataru Shinohara Alexander Shmakov Erin M. Sigel Filipe Soares de Souza Lana da Silva Sylvestre Weston Testo Luz Amparo Triana-Moreno Chie Tsutsumi Hanna Tuomisto IvAn A. Valdespino Alejandra Vasco Raquel Stauffer Viveros Alan Weakley Ran Wei Stina Weststrand Paul G. Wolf George Yatskievych Xiao-Gang Xu Yue-Hong Yan Liang Zhang Xian-Chun Zhang Xin-Mao Zhou | 2016 | Journal of Systematics and Evolution2016，54，6： | 44 |
| 3 | Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA显示文摘 | Luigi Warren Philip D. Manos Tim Ahfeldt Yuin-Han Loh Hu Li Frank Lau Wataru Ebina Pankaj K. Mandal Zachary D. Smith Alexander Meissner George Q. Daley Andrew S. Brack James J. Collins Chad Cowan Thorsten M. Schlaeger Derrick J. Rossi | 2010 | Cell Stem Cell2010，，5： | 4 |
| 4 | Underutilization of palliative care services in the liver transplant population显示文摘AIM To evaluate use of palliative care services in patients with end-stage liver disease who do not have access to liver transplant.METHODS Evaluated were end-stage liver disease patients who were removed from the liver transplant wait-list or died prior to transplant at a single transplant center over a 2-year period. Those who were removed due to noncompliance or ultimately transplanted elsewhere were excluded from this study. Patient characteristics associated with palliative care consultation were assessed using logistic regression analysis.RESULTS Six hundred and eighty-three patients were listed for liver transplant in 2013-2014 with 107(16%) dying(n = 62) or removed for clinical decompensation prior to liver transplant(n = 45): Median age was 58 years, and the majority were male(66%), Caucasian(53%), had Child C cirrhosis(61%) or hepatocellular carcinoma(52%). The palliative care team was consulted in only 18 of the 107 patients(17%) who died or were removed, 89% of which occurred as inpatients. Half of these consultations occurred within 72 h of death. In univariable analysis, patients of younger age, white race, and higher end-stage liver disease scores at time of listing and delisting were more likely to receive palliative care services. Only younger age [Odds ratio(OR) = 0.92; P = 0.02] and Caucasian race(OR = 4.90; P = 0.02) were still associated with integration of palliative care services through multivariable analysis.CONCLUSION Palliative care services are grossly underutilized in older, non-white patients with cirrhosis on the liver transplant wait-list. We encourage early integration of these services into clinical decision-making in the transplant population, with further studies aimed at understanding barriers to consultation. | Priya Kathpalia Alexander Smith Jennifer C Lai | 2016 | World Journal of Transplantation2016，6，3： | 3 |
| 5 | The Determinants of Chinese Outward Foreign Direct Investment:A Closer Look显示文摘Over the last fifteen years,China rapidly expanded its outward foreign direct investment (OFDI)through remarkable economic growth and the 'go global'policy.Chinese firms explored investment avenues especially in developing and emerging countries.As a result,China became the third largest contributor of OFDI.We examine the determinants of Chinese OFDI in 67 countries during the period lasting from 2006 to 2015 using the feasible generalized least square method.We find that the size of the economy,market opportunities,cost advantages due to low wage structure,ease of doing business, country risk,and geographical proximity are the prominent factors leading to changes in Chinese OFDI in developing and emerging economies.We find that China's investments in different developing and emerging countries are driven by a different set of factors and the determinants of Chinese OFDI vary in low and high per capita income countries. | Muhammad Zubair Mumtaz Zachary Alexander Smith | 2018 | Frontiers of Economics in China-Selected Publications from Chinese Universities2018，13，4： | 2 |
| 6 | China’s low-emission pathways toward climate-neutral livestock production for animal-derived foods显示文摘Animal-derived food production accounts for 19%of global anthropogenic greenhouse gas(GHG)emissions.Diet followed in China is ranked as lowcarbon emitting(i.e.,0.21 t CO_(2-)eq per capita in 2018,ranking at 145^(th) of 168 countries)due to the low average animal-derived food consumption rate,and preferential consumption of animal-derived foods with lower GHG emissions(i.e.,pork and eggs versus beef and milk). | Rong Wang Zhaohai Bai Jinfeng Chang Qiushuang Li Alexander N.Hristov Pete Smith Yulong Yin Zhiliang Tan Min Wang | 2022 | The Innovation2022，3，2： | 2 |
| 7 | Safety and efficacy of sofosbuvir/velpatasvir/voxilaprevir in postliver transplant patients with previous direct-acting antiviral failure:Six case reports显示文摘BACKGROUND Direct-acting antiviral(DAA)therapy regimens are highly effective at eliminating hepatitis C virus(HCV)infection but rates of sustained virologic response(SVR)are lower in patients with decompensated cirrhosis or hepatocellular carcinoma.Since many of these patients will be referred for liver transplant,they will require retreatment after transplantation.Sofosbuvir/velpatasvir/voxilaprevir(SOF/VEL/VOX)is recommended by guidelines as the preferred regimen to treat HCV in DAA-experienced patients following liver transplant however there is limited data.CASE SUMMARY We present the cases of six liver transplant recipients who had previous treatment failure with sofosbuvir-based DAA therapy prior to transplantation and who then received SOF/VEL/VOX after transplant.CONCLUSION This case series demonstrate the real-world efficacy and safety of SOF/VEL/VOX in the post liver transplant setting.Treatment was successful with all patients achieving SVR,it was well tolerated,and there were minimal drug-drug interactions with their immunosuppressants. | Cory Higley Christine C Hsu Coleman Smith Sandeep Nadella Alexander T.Lalos | 2020 | World Journal of Hepatology2020，12，12： | 2 |
| 8 | Markers of Inflammation and Cardiovascular Disease: Application to Clinical and Public Health Practice: A Statement for Healthcare Professionals From the Centers for Disease Control and Prevention and the American Heart Association显示文摘 | Thomas A. Pearson George A. Mensah R. Wayne Alexander Jeffrey L. Anderson Richard O. Cannon Michael Criqui Yazid Y. Fadl Stephen P. Fortmann Yuling Hong Gary L. Myers Nader Rifai Sidney C. Smith Kathryn Taubert Russell P. Tracy Frank Vinicor | 2003 | Circulation: Journal of the American Heart Association2003，，3： | 2 |
| 9 | Effect of stream channel size on the delivery of nitrogen to the Gulf of Mexico 显示文摘 | Alexander R B Smith R A Schwarz G E | 2000 | Nature2000，403，6771： | 1 |
| 10 | Thera- peutic Effect of Caffeine Treatment Immediately Following Neonatal Hypoxic-Ischemic Injury on Spatial Memory in Male Rats 显示文摘 | Alexander M Smith AL Rosenkrantz TS | 2013 | Brain Sci2013，3，1： | 1 |
| 11 | Quantification of 1,3 - beta - D - glucan levels in children: preliinary data for diagnostic use of the beta -glucan assay in a pediatric setting显示文摘 | Smith PB Benjamin DK Jr Alexander BD | 2007 | Clin Vaccine Immuno12007，14，： | 1 |
| 12 | Cannabinoids in the treatment of cancer显示文摘 | Alexander A Smith P F Rosengren R J | 2009 | Cancer Lett2009，285，1： | 1 |
| 13 | Evaluation of syndromic based on National Health Service Direct Derived Data-England and Wale显示文摘 | Alexander Doroshenko Cooper D Smith G | 2005 | MMWR2005，54，： | 1 |
| 14 | Immune Activation in Patients With Irritable Bowel Syndrome显示文摘 | Tobias Liebregts Birgit Adam Christoph Bredack Alexander R?th Susanne Heinzel Sue Lester Sarah Downie–Doyle Eric Smith Paul Drew Nicholas J. Talley Gerald Holtmann | 2007 | Gastroenterology2007，，3： | 1 |
| 15 | Glutamate-based depression GBD显示文摘 | Mccarthy DJ Alexander R Smith MA | | Med Hypotheses0，78，5： | 1 |
| 16 | Chimerism and tolerance in a recipient of a deceased-donor liver transplant显示文摘 | ALEXANDER S I SMITH N HU M | 2008 | N Engl J Med2008，358，4： | 1 |
| 17 | A comprehensive map of the porcine genome 显示文摘 | Rohrer G A Alexander L J Hu Z Smith T P L Keele JW Beattie C W | 1996 | Genome Res1996，6，： | 1 |
| 18 | Bisphenol A:acute aquatic toxity 显示文摘 | Alexander H Dill D Smith L | 1988 | Environ Toxicol Chem1988，7，： | 1 |
| 19 | New approaches to the treatment of dense deposit disease显示文摘 | Smith R J Alexander J Barlow P N | 2007 | J Am Soc Nephrol2007，18，9： | 1 |
| 20 | A Mitochondria-Targeted Macrocyclic Mn(II) Superoxide Dismutase Mimetic显示文摘 | Geoffrey F. Kelso Andrej Maroz Helena M. Cochemé Angela Logan Tracy A. Prime Alexander V. Peskin Christine C. Winterbourn Andrew M. James Meredith F. Ross Sally Brooker Carolyn M. Porteous Robert F. Anderson Michael P. Murphy Robin A.J. Smith | 2012 | Chemistry & Biology2012，，10： | 1 |
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