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| 1 | Assessment and management of low anterior resection syndrome after sphincter preserving surgery for rectal cancer显示文摘Many patients develop a variety of bowel dysfunction after sphincter preserving surgeries(SPS)for rectal cancer.The bowel dysfunction usually manifests in the form of low anterior resection syndrome(LARS),which has a negative impact on the patients'quality of life.This study reviewed the LARS after SPS,its mechanism,risk factors,diagnosis,prevention,and treatment based on previously published studies.Adequate history taking,physical examination of the patients,using validated questionnaires and other diagnostic tools are important for assessment of LARS severity.Treatment of LARS should be tailored to each patient.Multimodal therapy is usually needed for patients with major LARS with acceptable results.The treatment includes conservative management in the form of medical,pelvic floor rehabilitation and transanal irrigation and invasive procedures including neuromodulation.If this treatment failed,fecal diversion may be needed.In conclusion,Initial meticulous dissection with preservation of nerves and creation of a neorectal reservoir during anastomosis and proper Kegel exercise of the anal sphincter can minimize the occurrence of LARS.Pre-treatment counseling is an essential step for patients who have risk factors for developing LARS. | Ahmad Sakr Fozan Sauri Mohammed Alessa Eman Zakarnah Homoud Alawfi Radwan Torky Ho Seung Kim Seung Yoon Yang Nam Kyu Kim | 2020 | Chinese Medical Journal2020，，15： | 17 |
| 2 | Antifungal activity and antidiarrheal activity via antimotility mechanisms of (-)-fenchone in experimental models显示文摘BACKGROUND(-)-Fenchone is a bicyclic monoterpene present in essential oils of plant species,such as Foeniculum vulgare and Peumus boldus,used to treatment of gastrointestinal diseases.Pharmacological studies report its anti-inflammatory,antioxidant,and antinociceptive activity.AIM To investigate antidiarrheal activity related to gastrointestinal motility,intestinal secretion and antimicrobial activity.METHODS A castor oil-induced diarrhea model was used to evaluate antidiarrheal activity.Intestinal transit and gastric emptying protocols were used to assess a possible antimotility effect.Muscarinic receptors,presynaptic α2-adrenergic and tissue adrenergic receptors,KATP channels,nitric oxide were investigated to uncover antimotility mechanisms of action and castor oil-induced enteropooling to elucidate antisecretory mechanisms.The antimicrobial activity was evaluated in the minimum inhibitory concentration model,the fractional inhibitory concentration index using the(-)-fenchone association method with standard antifungal agents.RESULTS(-)-Fenchone(75,150 and 300 mg/kg)showed antidiarrheal activity,with a significant decrease in the evacuation index.This activity is possibly related to a percentage of reduced intestinal transit(75,150 and 300 mg/kg).The antimotility effect of(-)-fenchone decreased in the presence of pilocarpine,yohimbine,propranolol,L-NG-nitroarginine methyl ester or glibenclamide.In the enteropooling model,no reduction in intestinal fluid weight was observed.(-)-Fenchone did not show antibacterial activity;on the other hand,inhibits the growth of strains of fungi with a minimum fungicide concentration of 32μg/mL.However,when it was associated with amphotericin B,no synergism was observed.CONCLUSION The antidiarrheal effect of(-)-fenchone in this study involves antimotility effect and not involve antisecretory mechanisms.(-)-Fenchone presents antifungal activity;however,it did not show antibacterial activity. | Michelle Liz de Souza Pessoa Leiliane Macena Oliveira Silva Maria Elaine Cristina Araruna Catarina Alves de Lima Serafim Edvaldo Balbino Alves Junior Alessa Oliveira Silva Matheus Marley Bezerra Pessoa Hermes Diniz Neto Edeltrudes de Oliveira Lima Leonia Maria Batista | 2020 | World Journal of Gastroenterology2020，26，43： | 2 |
| 3 | Thermal bridging of graphene nanosheets via covalent molecular junctions: A non-equilibrium Green's functions-density functional tightbinding study显示文摘Despite the uniquely high thermal conductivity of graphene is well known,the exploitation of graphene into thermally conductive nanomaterials and devices is limited by the inefficiency of thermal contacts between the individual nanosheets.A fascinating yet experimentally challenging route to enhance thermal conductance at contacts between graphene nanosheets is through molecular junctions,allowing covalently connecting nanosheets,otherwise interacting only via weak Van der Waals forces.Beside the bare existence of covalent connections,the choice of molecular structures to be used as thermal junctions should be guided by their vibrational properties,in terms of phonon transfer through the molecular junction.In this paper,density functional tight-binding combined with Green's functions formalism was applied for the calculation of thermal conductance and phonon spectra of several different aliphatic and aromatic molecular junctions between graphene nanosheets.Effects of molecular junction length,conformation,and aromaticity were studied in detail and correlated with phonon tunnelling spectra.The theoretical insight provided by this work can guide future experimental studies to select suitable molecular junctions,in order to enhance the thermal transport by suppressing the interfacial thermal resistances.This is attractive for various systems,including graphene nanopapers and graphene polymer nanocomposites,as well as related devices.In a broader view,the possibility to design molecular junctions to control phonon transport currently appears as an efficient way to produce phononic devices and controlling heat management in nanostructures. | Diego Martinez Gutierrez Alessa ndro Di Pierro Alessa ndro Pecchia Leon ardo Medra no San donas Rafael Gutierrez Mar Bernal Bohayra Mortazavi Gianaurelio Cuniberti Guido Saracco Alberto Fina | 2019 | Nano Research2019，12，4： | 2 |
| 4 | Sarcopenia : prevalence and prognosticsignificance in hospitalized patients 显示文摘 | Gariballa S Alessa A | 2013 | Clin Nutr2013，32，5： | 1 |
| 5 | Towards a community framework for agent-based modeling显示文摘 | Janssen M A Barton C M Alessa L N | 2008 | Journal of Artificial Societies and Social Simulation2008，11，2： | 1 |
| 6 | Effects of knowledge,personal attribution and perception of ecosystem health on depreciative behaviors in the intertidal zone of Pacific Rim National Park and Reserve显示文摘 | Alessa L Bennett S M Kliskey A D | 2003 | Journal of Environmental Management2003，68，2： | 1 |
| 7 | Freshwater vulnerabilities and resilience on the Seward Peninsula: Integrating multiple dimensions of landscape change 显示文摘 | Alessa L Kliskey A Busey R | 2008 | Global Environmental Change - Human and Policy Dimensions2008，18，2： | 1 |
| 8 | The arctic water re- source vulnerability index: an integrated assessment tool for eommunity resilience and vulnerability with respect to fresh- water显示文摘 | Alessa L Kliskey A Iammers R | 2008 | Environmental Management2008，42，3： | 1 |
| 9 | Effects of Knowl- edge, Personal Attribution and Perception of Ecosystem Health on Depreciative Behaviors in the Intertidal Zone of Pacific Rim National Park and Reserve显示文摘 | Alessa L Bennett S M Kliskey A D | 2003 | Journal of En- vironmental Management2003，68，2： | 1 |
| 10 | Sarcopenia: prevalence and prognostic signifcance in hospitalized patients 显示文摘 | Gariballa S Alessa A | 2013 | Clin Nutr2013，32，： | 1 |
| 11 | Effects of soil compaction on root and root hair morphology: Implications for campsite rehabilitation 显示文摘 | Alessa L Earnhart C G | 2000 | USDA Forest Serv P2000，15，5： | 1 |
| 12 | Remote sensing the vulnerability of vegetation in natural terrestrial ecosystems显示文摘 | Alistair M.S. Smith Crystal A. Kolden Wade T. Tinkham Alan F. Talhelm John D. Marshall Andrew T. Hudak Luigi Boschetti Michael J. Falkowski Jonathan A. Greenberg John W. Anderson Andrew Kliskey Lilian Alessa Robert F. Keefe James R. Gosz | 2014 | Remote Sensing of Environment2014，，： | 1 |
| 13 | Freshwater Vulnerabilities and Resilience on the Seward Peninsula: Integrating Multiple Dimensions of Landscape Change显示文摘 | Alessa L Kliskey A Busey R | 2008 | Global Environmental Change2008，，18： | 1 |
| 14 | Freshwater Vulnerabilities and Resilience on the Seward Peninsula: Integrating Multiple Dimensions of Land- scape Change显示文摘 | ALESSA L KLISKEY A BUSEY R | 2008 | Global Environmental Change -Human and Policy Dimen- sions2008，18，2： | 1 |
| 15 | Manipulation under anaesthesia for the treatment of frozen shoulder显示文摘 | Hamdan TA AlEssa KA | 2003 | Int Orthop2003，27，3： | 1 |
| 16 | Triple synchronous primary neoplasms in the gastrointestinal tract显示文摘To the Editor:Most of the multiple primary malignancies are metachronous or involve more than one system,we instead describe a case with synchronous triple cancers involving one organ system.This study was approved by the Institutional Review Board of Severance hospital,Yonsei University(IRB No.4-2019-0889).A 61-year old man who had no chronic illness,underwent abdominal computerized tomography(CT)scan due to vague abdominal complains and was found to have descending colon wall thickening[Figure 1A],colon cancer(cT3N+)was suspected.He is not smoker or alcohol drunker,and has no family history of malignancies. | Fozan Mohammed Sauri Eman Adnan Zakarneh Mohammed Yousef Alessa Ahmad Hammad Sakr Yeon Seung Chung Ho Seung Kim Nam kyu Kim | 2021 | Chinese Medical Journal2021，，10： | 0 |
| 17 | Visual resolution under photopic and mesopic conditions in patients with Sjogren's syndrome显示文摘AIM:To focus on different visual resolution tasks under photopic and mesopic conditions in Sjogren’s syndrome patients compared to age-matched healthy controls.METHODS:The visual resolution measurements included high and low visual acuities and contrast sensitivity functions.These tests were conducted under photopic and then mesopic conditions.Twenty-one Sjögren’s syndrome patients and 21 aged-matched healthy volunteers completed all the measurements in this study.RESULTS:Sjogren’s syndrome patients have greater impairment in contrast sensitivity than standardized visual acuity.This reduction was significant under the mesopic condition.Also,Sjogren’s syndrome patients treated with pilocarpine suffer more than patients without pilocarpine treatment under low light conditions.CONCLUSION:Sjogren’s syndrome patients shows greater impairment in different visual resolution tasks due to dry eye symptoms. | Mosaad Alhassan Amal Aldarwesh Issa Alessa Rafif Alhijji Reema Alduhayan Ali Almustanyir | 2023 | International Journal of Ophthalmology(English edition)2023，16，10： | 0 |
| 18 | Automatic Team Assignment and Jersey Number Recognition in Football Videos显示文摘Football is one of the most-watched sports,but analyzing players’per-formance is currently difficult and labor intensive.Performance analysis is done manually,which means that someone must watch video recordings and then log each player’s performance.This includes the number of passes and shots taken by each player,the location of the action,and whether or not the play had a successful outcome.Due to the time-consuming nature of manual analyses,interest in automatic analysis tools is high despite the many interdependent phases involved,such as pitch segmentation,player and ball detection,assigning players to their teams,identifying individual players,activity recognition,etc.This paper proposes a system for developing an automatic video analysis tool for sports.The proposed system is the first to integrate multiple phases,such as segmenting the field,detecting the players and the ball,assigning players to their teams,and iden-tifying players’jersey numbers.In team assignment,this research employed unsu-pervised learning based on convolutional autoencoders(CAEs)to learn discriminative latent representations and minimize the latent embedding distance between the players on the same team while simultaneously maximizing the dis-tance between those on opposing teams.This paper also created a highly accurate approach for the real-time detection of the ball.Furthermore,it also addressed the lack of jersey number datasets by creating a new dataset with more than 6,500 images for numbers ranging from 0 to 99.Since achieving a high perfor-mance in deep learning requires a large training set,and the collected dataset was not enough,this research utilized transfer learning(TL)to first pretrain the jersey number detection model on another large dataset and then fine-tune it on the target dataset to increase the accuracy.To test the proposed system,this paper presents a comprehensive evaluation of its individual stages as well as of the sys-tem as a whole. | Ragd Alhejaily Rahaf Alhejaily Mai Almdahrsh Shareefah Alessa Saleh Albelwi | 2023 | Intelligent Automation & Soft Computing2023，，6： | 0 |
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