|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 耦合湿地模块的流域水文模型模拟效率评价显示文摘耦合湿地模块的流域水文模型是开展流域湿地变化的水文效应及其水文功能评估的有效工具,其模拟效率直接关系到模拟精度和应用价值。选取中国湿地主要分布区之一的嫩江流域,利用PHYSITEL/HYDROTEL模型平台,构建孤立湿地和河滨湿地模块并与流域水文模型耦合,并从拟合优度指数和模拟效率角度评价了耦合湿地模块的流域水文模型模拟效率。结果表明,耦合湿地模块的流域水文模型,拟合和验证期间模型的拟合度指数均有所提高,嫩江富拉尔基和大赉水文站控制流域的Nash-Sutcliffe系数和克林效率系数平均提高了3.08%和4.64%,均方根误差和相对偏差平均降低了12.72%和55.93%,且整个研究时段模拟结果的流量指数总体更接近于观测的径流数据。可见,耦合湿地模块的流域水文模型可提高水文过程模拟精度,更好地定量评估湿地水文功能,为流域水资源精准调控与湿地修复保护提供重要支撑。 | 吴燕锋 章光新 齐鹏 Rousseau Alain N 胡宝军 宋峥 于成刚 | 2019 | 水科学进展2019，30，3： | 8 |
| 2 | Prevalence and virological profiles of hepatitis B infection in human immunodeficiency virus patients显示文摘AIM: To determine the prevalence of hepatitis B virus (HBV) in adult human immunodeficiency virus (HIV) patients with CD4+ T-cell count less than 500/mm 3 and without antiretroviral therapy; to describe different HBV-HIV coinfection virological profiles; and to search for factors associated with HBs antigen (HBsAg) presence in these HIV positive patients.METHODS: During four months (June through September 2006), 491 patients were received in four HIV positive monitoring clinical centers in Abidjan. Inclusion criteria: HIV-1 or HIV-1 and 2 positive patients, age ≥ 18 years, CD4+ T-cell count < 500/mL and formal and signed consent of the patient. Realized blood tests included HIV serology, CD4+ T-cell count, quantitative HIV RNA load and HBV serological markers, such as HBsAg and HBc antibody (anti-HBcAb). We performed HBeAg, anti-HBe antibody (anti-HBeAb), anti-HBc IgM and quantitative HBV DNA load in HBsAg positive patients. Anti-HBsAb had been tested in HIV patients with HBsAg negative and anti-HBcAb-positive. HBV DNA was also tested in 188 anti-HBcAb positive patients with HBsAg negative status and without anti-HBsAb. Univariate analysis (Pearsonχ 2 test or Fischer exact test) and multivariate analysis (backward step-wise selection logistic regression) were performed as statistical analysis. RESULTS: Mean age of 491 patients was 36 ± 8.68 years and 73.3% were female. Type-1 HIV was found in 97% and dual-type HIV (type 1 plus type 2) in 3%. World Health Organization (WHO) clinical stage was 1, 2, 3 and 4 respectively in 61 (12.4%), 233 (47.5%), 172 (35%) and 25 patients (5.1%). Median CD4+ T-cell count was 341/mm 3 (interquartile range: 221-470). One hundred and twelve patients had less than 200 CD4+ T-cell/mm 3 . Plasma HIV-1 RNA load was elevated (≥ 5 log 10 copies/mL) in 221 patients (45%). HBsAg and anti-HBcAb prevalence was respectively 13.4% and 72.9%. Of the 66 HBsAg positive patients, 22 were inactive HBV carriers (33.3%), 21 had HBeAg positive hepatitis (31.8%) and 20 had HBeAg negative hepatitis (30.3%). HBeAg and anti-HBeAb were indeterminate in 3 of them. Occult B infection prevalence (HBsAg negative, anti-HBcAb positive, anti-HBsAb negative and detectable HBV DNA) was 21.3%. Three parameters were significantly associated with the presence of HBsAg: male [odds ratio (OR): 2.2;P = 0.005; 95% confidence interval (CI): 1.3-3.8]; WHO stage 4 (OR: 3.2;P = 0.01;95% CI: 1.3-7.9); and aspartate aminotransferase (AST) level higher than the standard (OR: 1.9;P = 0.04; 95% CI: 1.02-3.8). CONCLUSION: HBV infection prevalence is high in HIV-positive patients. HBeAg positive chronic hepatitis and occult HBV infection are more frequent in HIVpositive patients than in HIV negative ones. Parameters associated with HBsAg positivity were male gender, AIDS status and increased AST level. | Koffi Alain Attia Serge Eholié Eugène Messou Christine Danel Sandrine Polneau Henri Chenal Thomas Toni Myreille Mbamy Catherine Seyler Naomi Wakasugi Thérèse N'dri-Yoman Xavier Anglaret | 2012 | World Journal of Hepatology2012，4，7： | 4 |
| 3 | Plasmon-Enhanced Photoluminescence of SiC Quantum Dots for Cell Imaging Applications显示文摘 | Yuriy Zakharko Tetiana Serdiuk Tetyana Nychyporuk Alain Gélo?n Mustapha Lemiti Vladimir Lysenko | 2012 | Plasmonics2012，，4： | 1 |
| 4 | Amphotericin B inhibits the generation of the serapie isoform of the prion protein in infected cultures显示文摘 | Alain M Noriyuki N Ollivier M | 2000 | J Virol2000，，： | 1 |
| 5 | Moving least squares response surface approximation: Formulation and metal forming applications显示文摘 | PIOTR B HAKIM N ALAIN R | 2006 | Computers & Structures2006，83，1718： | 1 |
| 6 | Apheis: Health Impact Assessment of Long-term Exposure to PM 2.5 in 23 European Cities显示文摘 | Elena Boldo Sylvia Medina Alain Tertre Fintan Hurley Hans-Guido Mücke Ferrán Ballester Inmaculada Aguilera | 2006 | European Journal of Epidemiology2006，，6： | 1 |
| 7 | Three generations of asynchronous microprocessors 显示文摘 | Alain J M Mika N Wong G G | 2003 | Design & Test of Computers2003，20，： | 1 |
| 8 | Amphotericin B inhibits the generation of the scrapie isoform of the prion protein in infected cultures显示文摘 | Alain M Noriyuki N Ollivier M | 2000 | J Virol2000，，： | 1 |
| 9 | Formation of flavor components by the reaction of amino acids and carbonyl compounds in mild conditions显示文摘 | LAURA P N DE REVEL G ALAIN B | 2000 | J Agric Food Chem2000，48，9： | 1 |
| 10 | Optimal component mode synthesis for medium frequency problem显示文摘 | MATHIEU H DANIEL N ALAIN C | | 0，，： | 1 |
| 11 | Starch nanocrystals with large chain surface modifications显示文摘 | WIM T MOHAMED N B ALAIN D | 2006 | Langmuir2006，22，10： | 1 |
| 12 | Anticoagulant low molecular weight fucans produced by radical process and ion exchange chromatography of high molecular weight fucans extracted from the brown seaweed Ascophyllum modosum显示文摘 | Alain N Frederic C Catherine B V | 1991 | Carbohydrate Research1991，289，： | 1 |
| 13 | Insulin and leptin induce glut4 plasma membrane translocation and glucose uptake in a human neuronal cell line by a phosphatidylinositol 3 - kinase - dependent mechanism显示文摘 | YACIR B NADIA N ALAIN A | 2006 | Endocrinology2006，147，5： | 1 |
| 14 | Preparation, properties and applications of polysaccharide nanocrystals in advanced functional nanomaterials: A review显示文摘 | Lin N Huang J Alain D | 2012 | Nanoscale2012，4，11： | 1 |
| 15 | The molecular physiology of ammonium uptake and retrieval显示文摘 | Nicolaus von Wirén Sonia Gazzarrini Alain Gojon Wolf B Frommer | 2000 | Current Opinion in Plant Biology2000，，3： | 1 |
| 16 | Radiocephalic fistula complicated by distal ischemia:treatment by ulnar artery dilatation显示文摘 | Alain R Luigi N Xavier R | 2010 | Cardio Int Radiol2010，33，： | 1 |
| 17 | Uhrastructural charac- teristics and morpHogenesis of porcine reproductive and respiratory syndrome virus propagated in the highly per- missive MARC - 145 cell clone显示文摘 | Dea S Sawyer N Alain R | 1995 | Adv Exp Med Bi- ol1995，380，： | 1 |
| 18 | The substitution pattern in cationised and oxidized potato starch granules显示文摘 | Robin M Alain B Kari N | 2000 | Carbonhydrate Research2000，329，3： | 1 |
| 19 | Moving least squares response surface approximation: Formulation and metal forming applicatons显示文摘 | PIOTR B HAKIM N ALAIN R | 2005 | Computers and Structures2005，83，： | 1 |
| 20 | The effects of water residence time on the biological quality in a distribution network 显示文摘 | ALAIN K FREDERIQUE N ALAIN D | 2003 | Water Research2003，19，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员