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| 1 | Etiology of fulminant hepatic failure:experience from a tertiary hospital in Bangladesh显示文摘BACKGROUND: Fulminant hepatic failure (FHF) is not uncommon in our clinical practice in Bangladesh. There was a rise in acute hepatitis E virus (HEV) in Bangladesh after the 2004 floods. At that time, most of the country was under water for more than a month, leading to sewage contamination of the water supply. The aim of this study was to investigate the etiology of FHF in Bangladesh. METHODS: In this retrospective study, 23 patients with FHF who presented with severe impairment of hepato- cellular function (i.e. encephalopathy, coagulopathy and jaundice) within 6 months of onset of symptoms were included. There were 17 men and 6 women, aged from 18 to 32 years. Four of the women were pregnant. Patients were tested for markers for common hepatotrophic viruses. A relevant history was taken and the Patient Record Book of the Unit was reviewed. RESULTS: 56.52% patients (13/23) had HEV infection, and all were anti-HEV IgM-positive tested by ELISA. HBV infection was detected in 34.78% patients (8/23), all of whom were tested positive for either HBsAg or anti-HBs IgM by ELISA. 8.7% patients (2/23) had a positive history for intake of alcohol and/or drugs. CONCLUSIONS: Acute HEV infection is the leading cause of FHF in Bangladesh. Sewage contamination of the water supply following floods contributes to a higher incidence of HEV infection. HBV infection is also important. | Mamun-Al Mahtab Salimur Rahman Mobin Khan Ayub Al Mamun Shahrin Afroz | 2008 | Hepatobiliary & Pancreatic Diseases International2008，7，2： | 5 |
| 2 | Latest development of double perovskite electrode materials for solid oxide fuel cells:a review显示文摘Recently,the development and fabrication of electrode component of the solid oxide fuel cell(SOFC)have gained a significant importance,especially after the advent of electrode supported SOFCs.The function of the electrode involves the facilitation of fuel gas diffusion,oxidation of the fuel,transport of electrons,and transport of the byproduct of the electrochemical reaction.Impressive progress has been made in the development of alternative electrode materials with mixed conducting properties and a few of the other composite cermets.During the operation of a SOFC,it is necessary to avoid carburization and sulfidation problems.The present review focuses on the various aspects pertaining to a potential electrode material,the double perovskite,as an anode and cathode in the SOFC.More than 150 SOFCs electrode compositions which had been investigated in the literature have been analyzed.An evaluation has been performed in terms of phase,structure,diffraction pattern,electrical conductivity,and power density.Various methods adopted to determine the quality of electrode component have been provided in detail.This review comprises the literature values to suggest possible direction for future research. | Shammya AFROZE AfizulHakem KARIM Quentin CHEOK Sten ERIKSSON Abul K.AZAD | 2019 | Frontiers in Energy2019，13，4： | 5 |
| 3 | Decoding the Regional~1700 Ma Deformational History from the Rocks of Big Thompson Canyon Region of Colorado Using Monazite Dating of Foliations Preserved within Garnet and Staurolite Porphyroblastic Phases显示文摘Dating of monazite grains preserved within foliations defining FIAs(foliation inflection/intersection axes preserved within porphyroblasts)have provided a detailed chronology of deformational and metamorphic events during a regional~1700 Ma orogeny,in Big Thompson region of the Colorado Rockies in the USA.FIAs controlled dating of monazite grains preserved within multiple-foliations of garnet and staurolite porphyroblast have complemented and potentially revolutionized all traditional dating approaches available.With this technique it is possible to accurately differentiate the | Afroz A Shah | 2009 | 地学前缘2009，16，S1： | 4 |
| 4 | Epidemiology of hepatitis B virus in Bangladeshi general population显示文摘BACKGROUND:Hepatitis B virus(HBV)is encountered sporadically the year round in Bangladesh.It results in a wide range of liver diseases,with asymptomatic acute hepatitis at one end to hepatocellular carcinoma(HCC)at the other end of the spectrum. METHODS:All 1018 individuals of different age groups and sex with varied religious,educational and social backgrounds were tested for HBsAg by ELISA.The positive samples were further tested by ELISA for HBeAg.Before testing,blood samples were preserved at-20℃.The study was conducted in a semi-urban location on the outskirts of Dhaka. RESULTS:Of the 1018 individuals,5.5%tested positive for HBsAg.None were tested positive for anti-HCV.Among the HBsAg-positive population,58.93%were HBeAg- positive and the rest 41.07%HBeAg-negative.There was a male predominance and those who were tested positive were mostly between 16 and 50 years of age.Major risk factors for exposure to HBV appeared to be injudicious use of injectable medications,treatment by unqualified, traditional practitioners,mass-vaccination against cholera and smallpox,barbers and body piercing. CONCLUSION:HBV remains a major cause of morbidity and mortality in Bangladesh and we have a long way to go before we may bid farewell to this deadly menace. | Mamun-Al Mahtab Salimur Rahman Md.Fazal Karim Mobin Khan Graham Foster Susannah Solaiman Shahrin Afroz | 2008 | Hepatobiliary & Pancreatic Diseases International2008，7，6： | 4 |
| 5 | 玫瑰茄花萼乙醇提取物的抗痛觉敏感、抗炎及止泻作用的实验研究(英文)显示文摘目的:研究玫瑰茄(Hibiscus sabdariffa)花萼的乙醇提取物的抗痛觉敏感、抗炎及止泻作用。方法:使用95%乙醇提取玫瑰茄花萼干品用于测定其功效。用小鼠扭体实验检测其抗痛觉敏感作用,二甲苯致耳水肿模型小鼠检测其抗炎症作用,蓖麻油致腹泻模型小鼠检测其止泻作用。结果:在乙酸致小鼠扭体实验中,玫瑰茄花萼的乙醇提取物对小鼠扭体的抑制与空白对照组相比差异有统计学意义(P<0.01),对二甲苯致耳水肿模型小鼠的耳水肿的抑制与空白对照组相比差异有统计学意义(P<0.01),且显著减少了蓖麻油致腹泻小鼠的排便次数并增加了排便间隔时间(P<0.01)。结论:本研究的结果证实了玫瑰茄花萼的乙醇提取物具有显著的抗痛觉敏感、抗炎及止泻作用,验证了其在传统医学中的应用。 | Md.Khadem Ali Ayesha Ashraf Nripendra Nath Biswas Utpal Kumar Karmakar Shamima Afroz | 2011 | 中西医结合学报2011，9，6： | 4 |
| 6 | Distinguishing and Correlating Multiple Phases of Metamorphism across Multiply Deformed Regions Using the Axes of Inclusion Trails in Porphyroblasts显示文摘FIA (在 porphyroblasts 以内保存的生叶变化 / 交叉轴) 的继任为变丑和变态提供相对时间规模。在原处在从如此的继任定义每 FIA 的生叶以内在石榴石和十字石 porphyroblasts 以内作为包括保存的独居石谷物标明日期提供一条严密途径给组织在变丑和变态的扩大时期上形成了的年龄。匹配的年龄和 FIA 前进证实这条途径的适用性加提供存取给不能另外坚定的过长的历史。在科罗拉多落基山脉的大汤普森区域的 Tectonism,美国关于在约 1761 点的 FIA 集合 1 定义的 SW-NE trending | Ahmad Afroz SHAH Asghar ALI | 2011 | Acta Geologica Sinica(English Edition)2011，85，4： | 3 |
| 7 | FIAs(Foliation Intersection/Inflection Axes) Preserved in Porphyroblasts,the DNA of Deformation:A Solution to the Puzzle of Deformation and Metamorphism in the Colorado,Rocky Mountains,USA显示文摘FIA 广泛地被使用超过一十年了解开变丑和变形难题。因为在岩石中的组合 layering 总是重新激活多重变丑在哪儿发生了, Orogenic 处理在历史或 orogenesis 挑战科学家期间早发展,几乎不离开在矩阵保存的生叶开发的历史的小证据。在科罗拉多的落基山脉的山麓丘陵,美国如果 porphyroblasts 没在影响了这些岩石的多重变丑事件期间成长或如果他们旋转了,当这些事件发生了,包含一直不是可区分的四个 FIA 集合(趋势) 的继任。当变丑继续了,他们表明两变丑和 isograds 的地点划分显著地变化了。 | SHAH Afroz Ahmad | 2009 | Acta Geologica Sinica(English Edition)2009，83，5： | 3 |
| 8 | Qualitative and quantitative analysis of goat ovaries, follicles and oocytes in view of in vitro production of embryos显示文摘Goat ovaries were collected from the slaughterhouse and categorized as right, left, corpus luteum (CL)-present and -absent group and evaluated on the basis of weight (g), length (cm), width (cm), number of follicles, follicles aspirated and number and state of cumulus-oocyte-complexes (COCs). Comparatively higher weight [(0.66±0.02) vs (0.64±0.02) g], length [(1.17±0.02) vs (1.11±0.02) cm] and width [(0.77±0.02) vs (0.74±0.02) cm] were found in right ovaries than those of left. On the other hand significantly (P<0.05) higher weight [(0.71±0.03) vs (0.64±0.01) g] and width [(0.76±0.03) vs (0.75±0.01) cm] were found in CL-present group than those of CL-absent group of ovaries. The left ovaries contained comparatively higher number of normal COCs [(1.06±0.09) per ovary] than right ovaries [(1.03±0.10) per ovary] and the similar trend was found in total number of fol-licles [(4.51±0.25) vs (4.30±0.23) per ovary] and follicles aspirated [(2.55±0.14) vs (2.52±0.12) per ovary]. But the total COCs per ovary was almost similar in both ovaries [right and left: (1.85±0.12) and (1.85±0.11) per ovary, respectively]. Higher number of total COCs [(1.87±0.09) vs (1.76±0.16) per ovary], total number of follicles [(4.45±0.19) vs (4.16±0.37) per ovary], follicles aspirated [(2.55±0.10) vs (2.48±0.21) per ovary] and normal COCs [(1.12±0.07) vs (0.76±0.14) per ovary] were found in CL-absent group than those of CL-present group of ovaries. | ISLAM M.R. KHANDOKER M.A.M.Y. AFROZ S. RAHMAN M.G.M. KHAN R.I. | 2007 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2007，8，7： | 3 |
| 9 | 印度讷尔默达水资源工程:实施可持续发展显示文摘本文强调了水资源开发对食物保证与总体社会经济发展的重要性。它描述了与现在正在萨特普拉尔和文迪亚山脉间的讷尔默达盆地实施的萨尔达萨罗瓦(讷尔默达)水资源工程(SSP)相关的管理课题。SSP工程是一项跨越4个邦,即中央邦、古吉拉特邦、马哈拉施特拉邦和拉贾斯坦邦的多功能联合工程。蓄水大坝将淹没37 533hm^2土地,其结果是导致这 4个邦245个村庄超过4万个家庭的搬迁。这个项目的正面效应是产生1450MW的电力,灌溉拉贾斯坦邦的巴尔梅尔和查罗区的75 000hm^2干旱土地及古吉拉特邦易受旱灾的180万hm^2的土地,以及环境改善等等。在讷尔默达盆地实施使用的对环境而言为可持续发展的生态系统途径,无论在人类居住方面还是在环境管理工程方面,均可在山区或者非山区加以推广。 | Afroz Ahmad 郑亚新 | 1999 | 人类环境杂志1999，28，5： | 2 |
| 10 | Evaluation of biomarkers, genetic mutations, and epigenetic modifications in early diagnosis of pancreatic cancer显示文摘BACKGROUND Pancreatic cancer(PC)is one of the deadliest malignancies with an alarming mortality rate.Despite significant advancement in diagnostics and therapeutics,early diagnosis remains elusive causing poor prognosis,marred by mutations and epigenetic modifications in key genes which contribute to disease progression.AIM To evaluate the various biological tumor markers collectively for early diagnosis which could act as prognostic biomarkers and helps in future therapeutics of PC in Kashmir valley.METHODS A total of 50 confirmed PC cases were included in the study to evaluate the levels of carbohydrate antigen 19-9(CA 19-9),tissue polypeptide specific antigen(TPS),carcinoembryonic antigen(CEA),vascular endothelial growth factor-A(VEGF-A),and epidermal growth factor receptor(EGFR).Mutational analysis was performed to evaluate the mutations in Kirsten rat sarcoma(KRAS),Breast cancer type 2(BRCA-2),and deleted in pancreatic cancer-4(DPC-4)genes.However,epigenetic modifications(methylation of CpG islands)were performed in the promoter regions of cyclin-dependent kinase inhibitor 2A(p16;CDKN2A),MutL homolog 1(hMLH1),and Ras association domain-containing protein 1(RASSF1A)genes.RESULTS We found significantly elevated levels of biological markers CA 19-9(P≤0.05),TPS(P≤0.05),CEA(P≤0.001),and VEGF(P≤0.001).Molecular genetic analysis revealed that KRAS gene mutation is predominant in codon 12(16 subjects,P≤0.05),and 13(12 subjects,P≤0.05).However,we did not find a mutation in DPC-4(1203G>T)and BRCA-2(617delT)genes.Furthermore,epigenetic modification revealed that CpG methylation in 21(P≤0.05)and 4 subjects in the promoter regions of the p16 and hMLH1 gene,respectively.CONCLUSION In conclusion,CA 19-9,TPS,CEA,and VEGF levels were significantly elevated and collectively have potential as diagnostic and prognostic markers in PC.Global data of mutation in the KRAS gene commonly in codon 12 and rare in codon 13 could augment the predisposition towards PC.Additionally,methylation of the p16 gene could also modulate transcription of genes thereby increasing the predisposition and susceptibility towards PC. | Bilal Rah Manzoor Ahmad Banday Gh Rasool Bhat Omar J Shah Humira Jeelani Fizalah Kawoosa Tahira Yousuf Dil Afroze | 2021 | World Journal of Gastroenterology2021，27，36： | 2 |
| 11 | Theoretical and experimental study on lipophilicity and wound healing activity of ginger compounds显示文摘Objective:To correlate the chromatographic and computational method to calculate lipophilicity of selected ginger compounds and to observe the effects of log P on wound healing.Methods:Mixtures of acetonitrile and water with acetonitrile content between 95%and 50%v/v in 5%increments were kept separately in 10 different chromatographic chambers,saturated with solvent for 2 h.Spots were observed under UV light atλ=254 nm p-anisaldehyde used as a spraying reagent Theoretical calculation was done using the Alogps 2.1 online program at www.vcclab.org/lab/alogps.For percentage wound contraction,five groups of animal(mice)(25-30 g)of either sex were selected.Wound were created on dorsal surface of animals using toothed forceps,scalpel and pointed scissors.The wound areas were calculated using vernier caliper.After making wound mice were orally administered 35 mg/kg 6-shogoal,6-gingerol,8-gingerol and 10-gingerol respectively.Croup E as the control group received tap water.Results:The Iipophilicity values determined in thin layer chromatography were correlated with the theoretically calculated various log P by linear regression analysis.Significant correlations were found between log P values calculated by software program and the experimental reversedphase thin-layer chromatography data.Order of wound healing property of ginger compounds is directly dependent on lipophilieity i.e.more lipophilic compound has highest activity.Conclusions:Experimentally determined lipophilieity(R_(MO))values were correlated with log P determined by software's and found satisfactory.Lipophilieity(R_(MO)is a useful parameter for the determination and prediction of biological activity of ginger compounds. | Mohammed Afroz Bakht Mohammed F.Alajmi Perwez Alam Aftab Alam Prawez Alam Tariq Mohammed Aljarba | 2014 | Asian Pacific Journal of Tropical Biomedicine2014，4，4： | 2 |
| 12 | The importance of visualization of appendix on abdominal ultrasound for the diagnosis of appendicitis in children: A quality assessment review显示文摘BACKGROUND:Ultrasound has the first line investigation role in the diagnosis of acute appendicitis in children.The purpose of this study was to perform a quality assessment review on the visualization rate of appendix on ultrasound in children in the community hospital setting.METHODS:A retrospective chart review of the abdominal ultrasound findings for the visualization of the appendix was performed on paediatric patients ranging from 5 to 18 years.Data were collected from the two community hospitals of Toronto by using hospital electronic medical record for the ultrasound findings in patients presented with abdominal pain.RESULTS:Data from two community hospitals indicated visualization rate of the appendix as 11.0%and 23.2%for site 1 and site 2 respectively.In cases where the ultrasound was repeated the visualization rate remains the same.A two-proportion z-test was performed to find whether the visualization of appendix increases the likelihood of diagnosing appendicitis.The results revealed that the visualization of an appendix(P=0.52),significantly improved the diagnosis of appendicitis(z=34,P<0.001).CONCLUSION:Visualization of an appendix on ultrasound increases the likelihood of correctly diagnosing appendicitis.In our study,we found low visualization rate of appendix on ultrasound that could be the result of many factors that contribute towards the low visualization rate of an appendix on ultrasound.Hence,the challenges in identifying appendix should be minimized to improve the visualization and diagnosis of appendicitis on ultrasound. | Muhammad Akhter Hamid Ruqiya Afroz Uqba Nawaz Ahmed Aneela Bawani Dilnasheen Khan Rabia Shahab Asim Salim | 2020 | World Journal of Emergency Medicine2020，11，3： | 2 |
| 13 | Dye and its removal from aqueous solution by adsorption: A review显示文摘 | Mustafa T. Yagub Tushar Kanti Sen Sharmeen Afroze H.M. Ang | 2014 | Advances in Colloid and Interface Science2014，，： | 2 |
| 14 | Successful treatment outcome of primary melioidosis pneumonia-a case report from Bangladesh显示文摘 | Afroze SR Rahman MR Barai L | 2016 | BMC Res Notes2016，9，1： | 1 |
| 15 | Plasma membrane calcium ATPase overexpression in arterial smooth muscle increases vasomotor responsiveness and blood pressure显示文摘 | Gros R Afroze T You X M | 2003 | Circ Res2003，93，7： | 1 |
| 16 | Q wavearea for stratification of global left ventricular infarct size:comparison to conventional ECG assessment using Selvester QRS-score显示文摘 | Weinsaft JW Kochav JD Afroz A | 2014 | Coron Artery Dis2014，25，2： | 1 |
| 17 | Mechanisms fornicotine in the development and progression of gastrointestinalcancers显示文摘 | Jensen K Afroze S Munshi MK | 2012 | Transl Gastrointest Cancer2012，1，： | 1 |
| 18 | Expression and functional analysis of granulocyte colony-stimulating factor receptors on CD34^++ cells in patients with myelodysplastic syndrome (MDS) and MDS-acute myeloid leukemia显示文摘 | TANVIRA AFROZE SULTANA HIRONORI HARADA KINRO ITO | 2003 | Br J Hematol2003，121，： | 1 |
| 19 | Plasma membrane calcium ATPase overexpression in arterial smooth muscle increases vasomotor responsiveness and blood pressure 显示文摘 | Gros R Afroze T You X-M | 2003 | Circ Res2003，93，： | 1 |
| 20 | Thyroid function in children with uephrotic syndrome 显示文摘 | Afroz S Khan AH Roy DK | 2011 | Mymensingh Med J2011，20，3： | 1 |
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