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| 1 | 无创胎儿游离DNA检测技术在产前胎儿非整倍体筛查中的应用评价显示文摘目的:探讨无创胎儿染色体非整倍体检测技术(non-invasive fetal trisomy test, NIFTY)在胎儿染色体非整倍体产前筛查应用中的特异性和灵敏度。方法利用新一代高通量并行测序技术对母体外周血中的胎儿游离DNA(cell-free DNA, cfDNA)进行定量分析,根据相应DNA含量的变化推断胎儿染色体的异常状况。结果2012年3月至2013年5月,检测孕12-24周的孕妇外周血标本,对233份已结束妊娠的孕妇数据进行分析评估。其中结果为染色体非整倍体高风险11例,低风险结果222例。在高风险病例中21三体5例;18三体3例;13三体1例;性染色体X0异常2例。所有高风险结果经细胞遗传学检测后确认与母血胎儿cfDNA检测结果一致,检测特异性100.0%。筛查低风险结果222例,均已分娩,临床证实为正常婴儿,检测灵敏度100.0%。结论无创胎儿游离DNA检测是一种很好的胎儿非整倍体异常的产前筛查技术。相对于目前普遍采用的孕早期或孕中期血清学产前筛查技术,胎儿cfDNA检测更加可靠,无创性的取样过程对孕妇和胎儿无损伤,具有更好的敏感度和特异性。 | 穆煜 王庆 孙芾 王厚芳 常玲 Afnan Masoud 唐莹 | 2014 | 北京医学2014，36，7： | 5 |
| 2 | Optical spin-symmetry breaking for high-efficiency directional helicity-multiplexed metaholograms显示文摘Helicity-multiplexed metasurfaces based on symmetric spin–orbit interactions (SOIs) have practical limits because they cannot provide central-symmetric holographic imaging. Asymmetric SOIs can effectively address such limitations, with several exciting applications in various fields ranging from asymmetric data inscription in communications to dual side displays in smart mobile devices. Low-loss dielectric materials provide an excellent platform for realizing such exotic phenomena efficiently. In this paper, we demonstrate an asymmetric SOI-dependent transmission-type metasurface in the visible domain using hydrogenated amorphous silicon (a-Si:H) nanoresonators. The proposed design approach is equipped with an additional degree of freedom in designing bi-directional helicity-multiplexed metasurfaces by breaking the conventional limit imposed by the symmetric SOI in half employment of metasurfaces for one circular handedness. Two on-axis, distinct wavefronts are produced with high transmission efficiencies, demonstrating the concept of asymmetric wavefront generation in two antiparallel directions. Additionally, the CMOS compatibility of a-Si:H makes it a cost-effective alternative to gallium nitride (GaN) and titanium dioxide (TiO2) for visible light. The cost-effective fabrication and simplicity of the proposed design technique provide an excellent candidate for high-efficiency, multifunctional, and chip-integrated demonstration of various phenomena. | Muhammad Ashar Naveed Muhammad Afnan Ansari Inki Kim Trevon Badloe Joohoon Kim Dong Kyo Oh Kashif Riaz Tauseef Tauqeer Usman Younis Murtaza Saleem Muhammad Sabieh Anwar Muhammad Zubair Muhammad Qasim Mehmood Junsuk Rho | 2021 | Microsystems & Nanoengineering2021，7，2： | 3 |
| 3 | Hydrochemical characteristics and water quality assessment for drinking and agricultural purposes in District Jacobabad,Lower Indus Plain,Pakistan显示文摘Undeniably water is of utmost importance while considering basic necessities.This investigation emphasized on the hydrochemical evaluation and drinking water quality assessment in District Jacobabad located in lower Indus plain,Pakistan.Certainly world's largest irrigation system emerged from Indus Basin,which is underlain by well transmissive aquifer resulting in higher water table.Water supply schemes with their water sources from ground water and surface water provide piped water for drinking purpose to the community.Water samples were collected from all the forty eight supply schemes of which thirty two were found nonfunctional.Analytical parameters were compared with World Health Organization(WHO)and Pakistan Water Quality Standards but adversely substantial samples were found nonpotable.Alkalinity,bicarbonate and nitrate met the standard safe limits while values for EC,TDS,hardness,cations and anions exceeded the limits in numerous samples.SPSS and ArcGIS softwares were used for statistical analysis and spatial distribution of parameters.Hydrochemical facies were developed and suitability assessment of water resources was examined for agricultural use.The ground water type was classified as Na-HCO3 type with high salinity and it required treatment prior to irrigation.The proposed research exhibited the probable drinking water contamination sources and it demanded instant actions to further protect the valuable drinking water resources in District Jacobabad. | Asfandyar Shahab Shihua Qi Muhammad Zaheer Audil Rashid Muhammad Afnan Talib Umer Ashraf | 2018 | International Journal of Agricultural and Biological Engineering2018，11，2： | 2 |
| 4 | Diagnostic and therapeutic value of selective salpingography and tubal catheterization in an unselected infertile population显示文摘 | Papaioannou S Afnan M Girling AJ | 2003 | Fertil Steril2003，79，3： | 1 |
| 5 | Long-term fertility prognosis following selective salpingography and tubal catheterization in women with proximal tubal blockage显示文摘 | Papaioannou S Afnan M Girling AJ | 2002 | Hum Reprod2002，17，9： | 1 |
| 6 | The Elaboration Theory's Procedure for Designing Instruction: hConceptual Approach显示文摘 | Charles M Reigeluth Afnan Darwazeh | 1982 | Journal of Instructional Development1982，，5： | 1 |
| 7 | The roleofselective salpingography and tubal catheterization in the management of the infertile couple显示文摘 | Papioannou S Afnan M Sharif K | 2004 | Curr Opin Obstet Gynecol2004，16，4： | 1 |
| 8 | Reducingthe dose of gonadotrephin-releasing hormone agonist on starting ovarian stimulation: effect on ovarian response and in-vitro fertilization outcome 显示文摘 | Elgendy M Afnan M Holder R | 1998 | Hum Reprod1998，13，： | 1 |
| 9 | Urinary hMG versus recombinant FSH for controlled ovarian hyperstimulation following an agonist long down regulation protocol in IVF or ICSI treatment : a systematic review and recta-analysis显示文摘 | Coomarasamy A Afnan M Cheema D | 2008 | HumReprod2008，23，2： | 1 |
| 10 | Diagnostic and therapeutic value of selective salpingography and tubal catheterization in an unselected infertile population 显示文摘 | Papaioannou S Afnan M Girling AJ | 2003 | Fertil Sterl2003，79，： | 1 |
| 11 | Urinary HMG versus recombinant FSH for controlled ovarian hyperstimulation following an agonist long down-regulation protocol in IVF or ICSI treatment: a systematic review and meta-analysis显示文摘 | Coomarasamy A Afnan M Cheema D | 2008 | Hum Reprod2008，23，2： | 1 |
| 12 | The effect on pregnancy rates of tubal perfusion pressure reductions achieved by guidewire tubal cathererization显示文摘 | Papaioannou S Afnan M GirLing A J | | 0，，08： | 1 |
| 13 | The role of selective salpingography and tubal catheterization in the management of the infertile couple显示文摘 | Papaionannou S Afnan M Sharif K | 2004 | Curr Opin Obstet Gynecol2004，16，4： | 1 |
| 14 | Long tem safety of fluoroscopically guided selective salp ingography and tubal catheterization显示文摘 | Papaioannou S Afnan M Cocmarasamy A | 2002 | Hum Reprod2002，17，： | 1 |
| 15 | Diagnostic and therapeutic value of selective salpingography and tubal catheterization in an unselected infertile population 显示文摘 | Papaioannou S Afnan M Girling A J | 2003 | Fertil Steril2003，79，3： | 1 |
| 16 | The effect on pregnancy rates of tubal perfusion pressure reductions achieved by guide-wire tubal catheterisation显示文摘 | Papaioannou S Afnan M Girling AJ | 2002 | Hum Reprod2002，17，8： | 1 |
| 17 | A postal survey of hydrosalpinx management prior to IVF in the United Kingdom显示文摘 | Afnan M Evans J | 2004 | Hum Reprod2004，19，4： | 1 |
| 18 | The effect on pregnancy rates of tubal perfusion pressure reductions achieved by guide - wire tubal catheterization 显示文摘 | Papaioannou S Afnan M Girling A J | 2002 | Hum Reprod2002，17，8： | 1 |
| 19 | A postal survey of hydrosalpinx management prior to IVF in the United Kingdom 显示文摘 | Hammadieh N Afnan M Evans J | 2004 | Hum Reprod2004，19，： | 1 |
| 20 | Tubal assessment tests: still have not found what we are looking for 显示文摘 | Papaioannou S Afnan M Jafettas J | 2007 | Reprod Biomed Online2007，15，4： | 1 |
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