| 2 | 扁桃斑鸠菊及非洲印楝叶的提取物对链脲佐菌素致糖尿病大鼠肝脏形态学及肝毒性标志物的影响(英文)显示文摘目的:研究扁桃斑鸠菊及非洲印楝叶的提取物对链脲佐菌素致糖尿病大鼠肝脏形态学、肝脏氧化性应激标志物及部分肝脏酶类的影响。方法:大鼠腹腔注射链脲佐菌素致糖尿病。不同治疗组大鼠分别口服扁桃斑鸠菊及非洲印楝叶的提取物(500mg/kg)或二甲双胍(150mg/kg),疗程8周,每周测量大鼠的血糖水平及体质量变化。8周后麻醉处死大鼠。取肝组织制成切片,希夫染色法染色,并测量肝匀浆中丙二醛和谷胱甘肽过氧化物酶的含量;下腔静脉采血,分离血浆,检测血浆中丙氨酸氨基转移酶和天冬氨酸氨基转移酶的活性。结果:二甲双胍及植物提取物均能显著改善糖尿病大鼠的血糖水平,且与糖尿病模型组相比,治疗组的体质量明显增加(P<0.05)。光学显微镜下,各组大鼠的肝脏形态学无明显差别。植物提取物治疗组大鼠的血浆丙氨酸氨基转移酶及天冬氨酸氨基转移酶的活性与正常对照组相比无明显变化(P>0.05),而丙二醛含量明显下降(P<0.05)。结论:扁桃斑鸠菊及非洲印楝叶的提取物对糖尿病大鼠有明显的降糖作用,而肝脏形态学及肝毒性标志物没有明显变化。 | Oluwole Busayo Akinola Gabriel Olaiya Omotoso Oluwafunmike Sharon Akinola Olufunke Olubusola Dosumu Esther Tomi Adewoye | 2011 | 中西医结合学报2011，9，12： | 2 |
| 8 | Assessment of Noise Exposure of Sawmill Workers in Southwest,Nigeria显示文摘Economic wood processing employs the use of industrial machines for cutting,shaping,milling,and sawing timber,thereby leading to the generation of high levels of noise.Published data from empirical studies have categorized noise as an environmental hazard of global significance.Furthermore,noise exposure limits for different industries and all the industrial machines available has not been formally established as it presently exists in developed nations around the world.Therefore,this study assessed the daily exposure of sawmills workers to noise in Southwestern Nigeria.Reconnaissance surveys were first carried out in Osun,Oyo,Ondo,Ekiti,Lagos,and Ogun States to select sawmills that were fully operational and fit for the study.Two fully functional sawmills in two cities of each State were eventually selected for data collection,making a total of 24 sawmills,while the Circular Machines(CM),Planer Machines(PM),and Band-saw Machines(BM)were the machines in each sawmill considered.Two machines each of CM,PM,and BM were considered in each sawmill,making a total of forty-eight(48)machines each of CM,PM,and BM.Sound data were collected between 7 am and 7 pm each day for six days(between Monday and Saturday)using Extech 407732 sound level meter and all stabilized measurements were taken three times at different intervals.The data collected were in three different periods:Machine No-work Period(NPm),Machine Idle Period(IPm),and Machine Working Period(WPm).A two–way Analysis of Variance(ANOVA)was carried out at P<0.05 to determine whether there is a significant difference in the sound level average before and after the break,for both the idle and working periods of the three machines considered.This was also done to determine whether there is a signifi-cant difference between the sound level average of the results collected during idle and working periods of the three machines.Noise Pollution Levels(Lnp)ranged from 83.20 dB(PM)to 107.65(BM)and 93.42(CM and PM)–116.00(BM)respectively,while IPm also gave the least noise pollution level of 95.79 dB and WPm gave the highest level of 102.88 dB.The results revealed that all the machines’Lnp values in the working period are more than the 90 dB acceptable limit the recommendation value of 90 dB while 89.6%of CMs,75%of PMs,and 89.6%of BM had their Lnp above 90 dB in the idle period respectively.The minimum and the maximum noise dose levels for IPm,WPm and overall are 0.09(BM)and 2.37(CM),0.50(CM),and 4.77(PM)and 0.69(BM)and 6.64(PM)respectively.The study found out that the fundamental contributing factors to the high noise levels in sawmills are poor machine maintenance,use of old and obsolete machines,poor housekeeping strategy,limited space,workers’negligence,lack of PPE,and lack of occupational safety training.The study recommends that proper workplace practices such as use of personal protective equipment,new and modern machines,training,and occupational safety programmes be implemented in the considered sawmills. | Abiola O.Ajayeoba Adewoye A.Olanipekun Wasiu A.Raheem Oluwaseun O.Ojo Ayowumi R.Soji-Adekunle | 2021 | Sound & Vibration2021，55，1： | 1 |
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