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| 1 | In vitro antioxidant,anti-diabetic,cholinesterase and tyrosinase inhibitory potential of fresh juice from Citrus hystrix and C.maxima fruits显示文摘In the present study,antioxidant potential,α-amylase,α-glucosidase,cholinesterase and tyrosinase inhibitory activity of fresh juice from indigenous fruits of Citrus hystrix and C.maxima(Red&White var.)were investigated using an in vitro model.The contents of total phenolics,tannins,and total flavonoids ranged between 836.90 and 909.52 mg gallic acid equivalent(GAE)/L,333.33 and 523.21 mg gallic acid equivalent(GAE)/L and 224.88 and 262.22 mg rutin equivalent/L,respectively.The antioxidant activity of fresh juice was evaluated by employing different in vitro assays such as reducing power assay,DPPH•,ABTS•+and•OH radical scavenging capacities,peroxidation inhibition activity,antihemolytic assay.In addition,75.55%–79.75%ofα-amylase and 70.68%–72.83%ofα-glucosidase enzyme inhibition characteristics were found under in vitro starch digestion bioassay.Also,all the juice samples exhibited excellent tyrosinase(76.95%–80.79%),acetylcholinesterase(75.71%–79.74%)andβ-glucuronidase inhibitory activity(68.13%–69.38%).These results indicated that fresh juice of C.hystrix and C.maxima(Red&White var.)could be used as a source of antioxidant agents,functional food and nutraceuticals.©2014 Beijing Academy of Food Sciences.Production and hosting by Elsevier B.V.All rights reserved. | Arumugam Abirami Gunasekaran Nagarani Perumal Siddhuraju | 2014 | Food Science and Human Wellness2014，3，1： | 8 |
| 2 | A comparative study on antioxidant potentials,inhibitory activities against key enzymes related to metabolic syndrome,and anti-inflammatory activity of leaf extract from different Momordica species显示文摘Momordica species are vegetable crops widely distributed in warmer regions of the world.In this work,we describe the antioxidant,enzyme inhibitory and anti-inflammatory effects of the leaves from three different species of Momordica.The present investigation was initially carried out to explore the possible link between antioxidant,enzyme inhibitory property of Momordica leaf extract and their total phenolic and flavonoid contents.The anti-inflammatory activity was tested by using carrageenan-induced paw edema.Our results illustrated an enhanced antioxidant power of wild species comparable with a commercial variety.In addition,the leaf extract of M.dioica(200 mg/kg)presented a significant anti-inflammatory activity toward carrageenan-induced paw edema in Wistar rats in comparison to indomethacin(10 mg/kg).The contents of flavonoids and total phenolic compounds could be correlated with the antioxidant and enzymes inhibition activities.The major bioactive compounds of phenolic acids and flavonoids such as gallic acid,chlorogenic acid,caffeic acid,ferulic acid,ellagic acid,catechin,rutin,and quercetin were identified.Our findings suggest that wild Momordica species contains higher potential antioxidant and anti-inflammatory activities than a commercial variety does,which could be tested as drug candidates against oxidative and inflammation-related pathological processes.©2014 Beijing Academy of Food Sciences.Production and hosting by Elsevier B.V.All rights reserved. | Gunasekaran Nagarani Arumugam Abirami Perumal Siddhuraju | 2014 | Food Science and Human Wellness2014，3，1： | 4 |
| 3 | Hepatoprotective effect of leaf extracts from Citrus hystrix and C.maxima against paracetamol induced liver injury in rats显示文摘The present investigation is aimed to evaluate the hepatoprotective effects of Citrus hystrix and Citrus maxima(Red and White variety)methanolic leaf extracts on paracetamol induced toxicity.Leaf extracts were given in the dose of 200 mg/kg body weight for 7 days and toxicity was induced by paracetamol(2 g/kg)on day 5.Silymarin(100 mg/kg body weight)was used as reference standard.On the 7th day animals were sacrificed and liver function markers(ALT,AST,ALP),total bilirubin and total protein in blood serums and hepatic antioxidants(SOD,CAT,GSH and GPx)in liver homogenate were estimated.The leaf extracts restored the liver function markers and hepatic antioxidants to the normal level than elevated levels noticed on paracetamol control at P<0.001.Reversal of hepatoarchitecture has also been registered.The present study shows that C.hystrix and C.maxima leaf extracts possess hepatoprotective action against paracetamol induced hepatotoxicity.©2015 Beijing Academy of Food Sciences.Production and hosting by Elsevier B.V.All rights reserved. | Arumugam Abirami Gunasekaran Nagarani Perumal Siddhuraju | 2015 | Food Science and Human Wellness2015，4，1： | 3 |
| 4 | Chrysoeriol ameliorates hyperglycemia by regulating the carbohydrate metabolic enzymes in streptozotocin-induced diabetic rats显示文摘The present study aimed to evaluate the effects of chrysoeriol from Cardiospermum halicacabum in streptozotocin induced Wistar rats.Thirty rats were categorized as control,diabetic control supplemented with 0,20 mg/kg chrysoeriol and 600μg/kg BW of glibenclamide for 45-day trial period.Our results indicated that the inclusion of chrysoeriol(20 mg/kg)showed a significant reduction in plasma glucose,hemoglobin and glycosylated hemoglobin level with a rising of plasma insulin sensitivity.Further,downregulated enzymes including glucose 6-phosphatase,fructose 1,6-bisphosphatase,and glycogen phosphorylase as well upregulated enzymes such as hexokinase,glucose-6-phosphate dehydrogenase,pyruvate kinase,and hepatic glycogen content.There was a diminish action found in liver glycogen synthase of tested rat with a rise in gamma-glutamyl transpeptidase,towards normal levels upon treatment with chrysoeriol.The histopathological study confirmed that renewal of the beta cells of pancreatic of chrysoeriol and glibenclamide treated rats.In addition,the molecular docking of chrysoeriol against glycolytic enzymes including hexokinase,glucose-6-phosphate dehydrogenase,pyruvate kinase,using Argus software shows chrysoeriol had greatest ligand binding energy as equivalent to glibenclamide,as a standard drug.Thus,chrysoeriol found to be non-toxic with potential regulation on glycemic control and upregulation of the carbohydrate metabolic enzymes. | Baskaran Krishnan Abirami Ramu Ganesan Ravindran Balasubramani Dinh Duc Nguyen Soon Woong Chang Shaoyun Wang Jianbo Xiao Balamuralikrishnan Balasubramanian | 2020 | Food Science and Human Wellness2020，9，4： | 3 |
| 5 | Food prospects and nutraceutical attributes of Momordica species:A potential tropical bioresources–A review显示文摘Plants with potential therapeutic values have been used from time immemorial to cure various ailments and infectious diseases.Of late,scientific evidences have been provided on the potential therapeutic agent exhibited by certain traditionally used vegetable extracts.The importance of wild edible plants may be traced to antiquity but systemic studies are recent.All the Momordica species have been consumed as vegetable and traditionally used for various disorders.The whole plant parts are ascribed to possess the anti-diabetic effect in traditional medicinal system.The active constituents of Momordica plant parts were cucurbitane type triterpenoids,phenolics,glycosides,and several kinds of peptides including Momordica anti-HIV protein(MAP 30).Recent reports revealed the presence of several kinds of cucurbitane type triterpenoids in leaf,stem and fruits of Momordica species having several pharmacological activities.There is lack of scientific information available on the wild species which also having several bioactive components with potential activities.So the present review compares and highlights the current knowledge of the nutritional value,phytochemistry and physiological effects of wild species with known variety. | Gunasekaran Nagarani Arumugam Abirami Perumal Siddhuraju | 2014 | Food Science and Human Wellness2014，3，3： | 3 |
| 6 | Seaweed nutraceuticals and their therapeutic role in disease prevention显示文摘There is a growing interest that bioactive compounds from seaweed can play a major therapeutic role in disease prevention in humans.Seaweed bioactives including polysaccharides,pigments,fatty acids,polyphenols and peptides have been proven to possess various beneficial biological properties that could potentially contribute to functional food and nutraceutical development.These bioactive are explored for functional properties such as antioxidant,antibacterial,anticancer,antidiabetic,antitumor,antiviral,anti-inflammatory and anticoagulant properties,both in an in-vitro and in-vivo model system.This review critically examines the existing scientific knowledge on primary and secondary metabolites from seaweed and their functional properties for health-related conditions.It presents an update on the most recent evidence relating to their effect on health-related conditions and their action on cellular metabolism.Recent advancement and challenges for seaweed bioactive as a nutraceutical in relation to their biocompatibility and bioavailability to understand their therapeutic development is discussed. | Abirami R.Ganesan Uma Tiwari Gaurav Rajauria | 2019 | Food Science and Human Wellness2019，8，3： | 2 |
| 7 | Trends in Word Sense Disambigua-tion显示文摘 | Bhala R V V Abirami S | 2014 | Artificial Intelligence Review2014，42，2： | 1 |
| 8 | Preliminary study on the antimicrobial activity of Enicostemma littorale using different solvents显示文摘Objective:To study the antimicrobial activity of Enicostemma littorale(E.littorale) using different solvents.Methods:Chloroform,methanol and acetone extracts of different parts of E.littorale(leaf,stem and root) were evaluated for antimicrobial activity using disc diffusion method against some gram-negative species such as Escherichia coli,Klebsiella pnemoniae, Pseudomonas aeruginosa,Salmonella typhi and gram-positive species Staphylococcus aureus, Bacillus cereus,Bacillus subtilis and two fugal species viz.,Aspergillus fumigates and Aspergillus flavus.Results:The chloroform extracts showed the highest antibacterial activity.Among leaf, stem and root extracts,the stem extracts showed maximum antibacterial activity.All of the used extracts had no significant antifungal activity against Aspergillus fumigates and Aspergillus flavus.The chloroform stem extract showed highest activity(about 20 mm inhibition zone) against Bacillus subtilis(at 500 tng/mL) followed by the methanolic stem extract which showed highest activity against the same organism.The lowest antibacterial activity was observed by the acetone leaf extract(about 8 mm inhibition zone) against Escherichia coli.Conclusions:The findings of the study indicate littorale could also be a new source for antibiotics discovery. | Pitchamuthu Abirami Muthiah Gomathinayagam Rajaram Panneerselvam | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，7： | 1 |
| 9 | A cytosolic glutathione s-transferase, GST- theta from freshwater prawn Macrobrachium rosenbergii : molecular and biochemical properties显示文摘 | Jesu Arockiaraj Annie J. Gnanam Rajesh Palanisamy Prasanth Bhatt Venkatesh Kumaresan Mukesh Kumar Chaurasia Mukesh Pasupuleti Harikrishnan Ramaswamy Abirami Arasu Akila Sathyamoorthi | 2014 | Gene2014，，： | 1 |
| 10 | Hyperinsulinemia-induced vascular smooth muscle cell (VSMC) migration and proliferation is mediated by converging mechanisms of mitochondrial dysfunction and oxidative stress显示文摘 | Shiny Abhijit Regin Bhaskaran Abirami Narayanasamy Anand Chakroborty Nagaraj Manickam Madhulika Dixit Viswanathan Mohan Muthuswamy Balasubramanyam | 2013 | Molecular and Cellular Biochemistry2013，，1： | 1 |
| 11 | Stabilization of type I collagen using dialdehyde cellulose 显示文摘 | Swama Vinodh Kanth Abirami Ramaraj | 2009 | Process Biochemistry2009，，44： | 1 |
| 12 | Species Classification of Aquatic Plants Using GRNN and BPNN显示文摘 | ABIRAMI S RAMALINGAM V PALANIVEL S | 2014 | AI & SOCIETY2014，29，1： | 1 |
| 13 | In vitro evaluation of the an- tifungal activity of toothpastes 显示文摘 | C P Abirami P V Venugopal | 2005 | Journal of Medical My-cology2005，15，4： | 1 |
| 14 | A process-oriented perspective on differential business value creation by information technology: An empirical investigation显示文摘 | Abirami Radhakrishnan Xingxing Zu Varun Grover | 2006 | Omega2006，，6： | 1 |
| 15 | Effect of biologically synthesized silver nanoparticles on Bacopa monnieri (Linn.) Wettst. plant growth metabolism显示文摘 | C. Krishnaraj E.G. Jagan R. Ramachandran S.M. Abirami N. Mohan P.T. Kalaichelvan | 2012 | Process Biochemistry2012，，4： | 1 |
| 16 | Analysis of rice granules using image processing and neural net-work pattern recognition tool显示文摘 | ABIRAMI S NEELAMEGAM P KALA H | 2014 | International journal of com-puter applications2014，96，7： | 1 |
| 17 | Arrows in Chemistry 显示文摘 | S Abirami Lakshminarayanan | 2010 | Reso- nance2010，，1： | 1 |
| 18 | IC journal master list显示文摘 | Nagavalli D Abirami G Kumar S K | 2011 | Journal of Pharmacy Research2011，4，6： | 1 |
| 19 | IC journal master list显示文摘 | Nagavalli D Abirami G Kumar S K | 2011 | J pharm Res2011，4，6： | 1 |
| 20 | Linear Scheduling Strategy for Resource Allocation in Cloud Environment显示文摘 | Abirami S P Shalini R | 2012 | Journal on Cloud Computing:Services and Architecture2012，2，1： | 1 |
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