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| 1 | Perivascular epithelioid cell tumor of the liver coexisting with a gastrointestinal stromal tumor显示文摘Approximately 10% of patients with gastrointestinal stromal tumors (GIST) develop other neoplasms, either synchronously or metachronously. In this report we describe coexistence of a gastrointestinal stromal tumor and a hepatic perivascular epithelioid cell tumor (PEComa) in a 51-year-old woman with no evidence of tuberous sclerosis. A subcapsular hepatic nodule (0.8 cm in diameter) was found during surgery for symptomatic gastric neoplasm (15 cm in diameter) arising from the lesser curvature. Both tumors revealed histomorphological and immunohistochemical features confirming a diagnosis of a small incidental hepatic PEComa and a high risky extramural gastric GIST, respectively. The patient remained disease-free 25 mo after surgery with no evidence of tumor recurrence or new neoplasms. To our knowledge, this is the first report of PEComa in a patient with GIST. Hepatic lesions detected synchronously or metachronously in patients with GISTs may represent histogenetically distinct lesions and should be sampled to confirm or exclude metastatic GISTs. | Carlos Eduardo Paiva Francisco Alves Moraes Neto Abbas Agaimy Maria Aparecida Custódio Domingues Silvia Regina Rogatto | 2008 | World Journal of Gastroenterology2008，14，5： | 6 |
| 2 | Lymph node metastasis in gastrointestinal stromal tumours (GIST) occurs preferentially in young patients ≤40?years: an overview based on our case material and the literature显示文摘 | Abbas Agaimy Peter H. Wünsch | 2009 | Langenbeck’s Archives of Surgery2009，，2： | 3 |
| 3 | Nature:研究鉴定出侵袭性胰腺癌细胞及其弱点显示文摘在一项新的研究中,来自美国德州大学MD安德森癌症中心的研究人员利用患者源性肿瘤异种移植(patient—derived tumorxenograft,PDx)和模式小鼠开展一系列临床前实验,鉴定出一种门卫蛋白(gatekee Perprotein)阻止胰腺癌细胞转化为一种极具侵袭性的细胞类型,并且也发现剔除这种门卫蛋白的疗法能够阻止这些癌细胞。这些发现有助为携带这种进展迅速的治疗抵抗性的胰腺癌细胞亚群的患者开发出潜在的疗法。 | Genovese, Giannicola Carugo, Alessandro Tepper, James Robinson, Frederick Scott Li, Liren Svelto, Maria Nezi, Luigi Corti, Denise Minelli, Rosalba Pettazzoni, Piergiorgio Gutschner, Tony Wu, Chia-Chin Seth, Sahil Akdemir, Kadir Caner Leo, Elisabetta Amin, Samirkumar Dal Molin, Marco Ying, Haoqiang Kwong, Lawrence N. Colla, Simona Takahashi, Koichi Ghosh, Papia Giuliani, Virginia Muller, Florian Dey, Prasenjit Jiang, Shan Garvey, Jill Liu, Chang-Gong Zhang, Jianhua Heffernan, Timothy P. Toniatti, Carlo Fleming, Jason B. Goggins, Michael G. Wood, Laura D. Sgambato, Alessandro Agaimy, Abbas Maitra, Anirban Roberts, Charles W. M. Wang, Huamin Viale, Andrea DePinho, Ronald A. Draetta, Giulio F. Chin, Lynda | 2017 | 现代生物医学进展2017，17，14： | 2 |
| 4 | Gastrointestinal stromal tumours: a regular origin in the muscularis propria, but an extremely diverse gross presentation显示文摘 | Abbas Agaimy Peter H. Wünsch | 2006 | Langenbeck’s Archives of Surgery2006，，4： | 1 |
| 5 | Cytokeratin-positive epithelioid angiosarcoma presenting in the tonsil: a diagnostic challenge显示文摘 | Abbas Agaimy Hanspeter Kirsche Sabine Semrau Heinrich Iro Arndt Hartmann | 2012 | Human Pathology2012，，7： | 1 |
| 6 | Sustained treatment response of metastatic hepatocellular carcinoma with bevacizumab and sorafenib显示文摘The overall survival for patients with advanced hepatocellular carcinoma(HCC)is still limited.Although the multi-kinase inhibitor sorafenib has recently been approved for this disease,response rates are still low and patients often face dose-limiting toxicities which lead to a reduction in prognosis and treatment success.We here report a patient with metastasized HCC who shows a sustained response for more than 30 mo to sorafenib therapy after failure of a first line therapy with gemcitabine,oxaliplatin and bevacizumab. | Christina Wich Abbas Agaimy Deike Strobel Thaddaus Till Wissniowski Arndt Hartmann Matthias Ocker | 2010 | World Journal of Gastroenterology2010，16，28： | 1 |
| 7 | Gastrointestinal stromal tumours: a regular origin in the muscularis propria, but an extremely diverse gross presentation显示文摘 | Abbas Agaimy Peter H. Wünsch | 2006 | Langenbeck’s Archives of Surgery2006，，4： | 1 |
| 8 | Cytokeratin-positive epithelioid angiosarcoma presenting in the tonsil: a diagnostic challenge显示文摘 | Abbas Agaimy Hanspeter Kirsche Sabine Semrau Heinrich Iro Arndt Hartmann | 2012 | Human Pathology2012，，7： | 1 |
| 9 | Occurrence of other malignancies in patients with gastrointestinal stromal tumors显示文摘 | Abbas Agaimy Peter H. Wünsch Leslie H. Sobin Jerzy Lasota Markku Miettinen | 2006 | Seminars in Diagnostic Pathology2006，，2： | 1 |
| 10 | Sporadic Cajal cell hyperplasia is common in resection specimens for distal oesophageal carcinoma显示文摘 | Abbas Agaimy Peter H. Wünsch | 2006 | Virchows Archiv2006，，3： | 1 |
| 11 | Primary and metastatic cardiac tumors : imaging characteristics, surgical treatment, and histopathological spectrum: a 10-year-experience at a German heart center 显示文摘 | Thomas Strecker Johannes Roscha Michael Weyanda Abbas Agaimy | 2012 | Cardiovascular Pathology2012，21，： | 1 |
| 12 | Lymph node metastasis of carcinomas of transverse colon including flexures. Consideration of the extramesocolic lymph node stations显示文摘 | Aristotelis Perrakis Klaus Weber Susanne Merkel Klaus Matzel Abbas Agaimy Carol Gebbert Werner Hohenberger | 2014 | International Journal of Colorectal Disease2014，，10： | 1 |
| 13 | Gastrointestinal stromal tumours: a regular origin in the muscularis propria, but an extremely diverse gross presentation显示文摘 | Abbas Agaimy Peter H. Wünsch | 2006 | Langenbeck’s Archives of Surgery2006，，4： | 1 |
| 14 | Multiple sporadic gastrointestinal stromal tumours arising at different gastrointestinal sites: pattern of involvement of the muscularis propria as a clue to independent primary GISTs显示文摘 | Abbas Agaimy Bruno M?rkl Hans Arnholdt Peter H. Wünsch Luigi M. Terracciano Stephan Dirnhofer Arndt Hartmann Luigi Tornillo Michel P. Bihl | 2009 | Virchows Archiv2009，，2： | 1 |
| 15 | In vivo detection of mucosal healing-involved histiocytes by confocal laser endomicroscopy显示文摘Histiocytes have a pivotal role in wound repair and intestinal epithelial recovery-the most important goal to sustain gut functionality.Yet,an in vivo description of colonic histiocytes by confocal laser endomicroscopy(CLE) is missing.Here,we report the case of a 45-yearsold male patient who was referred to our clinic with weight loss and a history of two consecutive Clostridium difficile colitis episodes,the latter cured 3 wk before present admission.Stool microbiology was negative.Conventional colonoscopy showed atrophy and a light mucosal oedema in the distal colon.During on-going endoscopy,we performed a fluorescein-aided CLE which revealed large polygonal(histiocytes-like) cells with copious cytoplasm and large nuclei in the lamina propria of the sigmoid colon as well as regenerative epithelial changes.Histopathological assessment of biopsies from the same areas confirmed the endomicroscopical findings:Periodic acid-Schiff-and CD68-positive foamy histiocytes in the colonic lamina propria and an advanced epithelial recovery.Since stool microbiology was repeatedly negative and polymerase chain reaction-analysis from colonic biopsies could not detect any mRNA for Thropheryma whippleii and common pathogens,we interpreted this particular setting as a mucosal healing process after consecutive Clostridium difficile infections.In conclusion,by describing these colonic histiocytes,we highlight the clinical usefulness of CLE in describing the entity of histiocytes in vivo and in real-time during the process of post-infectious mucosal healing in the colon. | Gheorghe Hundorfean Abbas Agaimy Mircea T Chiriac Walter GeiBdrfer Jochen Wacker Markus F Neurath Jonas Mudter | 2012 | World Journal of Gastroenterology2012，18，32： | 0 |
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