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| 1 | From diagnosis to treatment of hepatocellular carcinoma: An epidemic problem for both developed and developing world显示文摘Hepatocellular carcinoma(HCC) is the most frequent primary liver malignancy and the third cause of cancer-related death in the Western Countries. The well-established causes of HCC are chronic liver infections such as hepatitis B virus or chronic hepatitis C virus, nonalcoholic fatty liver disease, consumption of aflatoxins and tobacco smocking. Clinical presentation varies widely; patients can be asymptomatic while symptomatology extends from right upper abdominal quadrant paint and weight loss to obstructive jaundice and lethargy. Imaging is the first key and one of the most important aspects at all stages of diagnosis, therapy and follow-up of patients with HCC. The Barcelona Clinic Liver Cancer Staging System remains the most widely classification system used for HCC management guidelines. Up until now, HCC remains a challenge to early diagnose, and treat effectively; treating management is focused on hepatic resection, orthotopic liver transplantation, ablative therapies, chemoembolization and systemic therapies with cytotocix drugs, and targeted agents. This review article describes the current evidence on epidemiology, symptomatology, diagnosis and treatment of hepatocellular carcinoma. | Dimitrios Dimitroulis Christos Damaskos Serena Valsami Spyridon Davakis Nikolaos Garmpis Eleftherios Spartalis Antonios Athanasiou Demetrios Moris Stratigoula Sakellariou Stylianos Kykalos Gerasimos Tsourouflis Anna Garmpi Ioanna Delladetsima Konstantinos Kontzoglou Gregory Kouraklis | 2017 | World Journal of Gastroenterology2017，23，29： | 44 |
| 2 | Effects of terlipressin versus splenectomy on liver regeneration after partial hepatectomy in rats: What we know so far?显示文摘We read with great interest the article entitled ‘‘Comparative study of the effects of terlipressin versus splenectomy on liver regeneration after partial hepatectomy in rats’’ by Ulmer et al. [1]. The aim of this study was to analyse the impact of terlipressin versus splenectomy on postoperative liver function and liver regeneration in rats undergoing 70% partial hepatectomy. Ulmer and his colleagues concluded that neither the administration of terlipressin nor splenectomy improved liver regeneration after 70% partial hepatectomy in rats. This is a very interesting research in our understanding regarding the study of postoperative liver failure and liver regeneration after modulation of portal vein pressure. However, there are some questions which demand further consideration. | antonios athanasiou eleftherios spartalis mairead hennessy michael spartalis demetrios moris christos damaskos emmanouil pikoulis | 2018 | Hepatobiliary & Pancreatic Diseases International2018，17，1： | 5 |
| 3 | 不同体积碱性盐对50∶50聚乳酸-聚乙二醇酸体外降解的影响显示文摘目的探讨不同体积碱性盐对生物降解植入物聚乳酸(PLA)-聚乙二醇酸(PGA)(50∶50PLA-PGA)体外降解的影响。方法在50∶50PLA-PGA中添加不同体积的碳酸钙(CC)和碳酸氢钠(SBC),观察降解过程pH值,标本的分子量、大小、生物力学性质的变化。结果50∶50PLA-PGA中加入CC、SBC能代偿代谢物导致的pH值下降,但CC组降解过程减慢。结论50∶50PLA-PGA中适当添加SBC,不影响该材料的正常降解,又能代偿降解过程pH值的变化。 | 林建华 Agrawal CM Zhu Chongfang Athanasiou KA | 1998 | 福建医科大学学报1998，32，4： | 5 |
| 4 | 一种用于手术辅助正畸的新型3D打印计算机辅助压电截骨导板显示文摘目前已广泛报道了旨在促进正畸牙移动的牙槽外科干预。然而,在日常实践中,仍然会发生意外事件或并发症。本研究的目的是提供一种新型的三维(3D)计算机辅助压力切割导向器(CAPG),其设计为半透明,以增加可见度,用于在引导期间增强支撑,多孔结构利于在术中通过大量滴水降温。这种设计可以起到最小化手术并发症的作用。为此,作者提出一种新型3D打印CAPG,以促进微创牙周加速骨生成正畸(PAOO),为手术提供更好的准确性、足够的可见性和更多的冷却剂进入手术部位的通道。通过导航CBCT数据,可以精确了解皮质骨厚度、牙根方向以及个体情况下解剖结构之间的相互关系,以便能够根据操作者的知识设计切割槽,获得所需的长度和深度。 | Donahue RP Hu JC Athanasiou KA 赵泽亮 | 2019 | 中国口腔颌面外科杂志2019，17，3： | 5 |
| 5 | Inferior mesenteric arteriovenous fistula: Case report and world-literature review显示文摘Arteriovenous fistulas between the inferior mesenteric artery and vein are rare, with only 26 primary and secondary cases described in the literature. Secondary fistulas occur following operations of the left hemicolon and manifest as abdominal pain, abdominal mass, gastrointestinal bleeding, colonic ischemia and portal hypertension. Symptom intensities are flow-dependent, and can range from minimal symptoms to severe heart failure due to left to right shunt. Diagnosis is usually established by radiological or intraoperative examination. Treatment options include embolization and/or surgical resection. Therapeutic decisions should be adapted to the unique characteristics of the fistula on an individual basis. A new case of a primary arteriovenous fistula is described and discussed along with a complete review of the literature. The patient in this report presented with signs and symptoms of colonic ischemia without portal hypertension. The optimal treatment for this pa-tient required a combination of embolization and surgical operation. The characteristics of these rare inferior mesenteric arteriovenous fistulas are examined and some considerations concerning diagnostic and therapeutic strategies that should be followed are presented. | Antonios Athanasiou Adamantios Michalinos reas Alexrou Sotirios Georgopoulos Evangelos Felekouras | 2014 | World Journal of Gastroenterology2014，20，25： | 5 |
| 6 | Natural orifice translumenal endoscopic surgery: critical appraisal of applications in clinical practice显示文摘 | Mikael H. Sodergren James Clark Thanos Athanasiou Julian Teare Guang-Zhong Yang Ara Darzi | 2009 | Surgical Endoscopy2009，，4： | 4 |
| 7 | Laparoscopic Versus Open Surgery for Rectal Cancer: A Meta-Analysis显示文摘 | Omer Aziz Vasilis Constantinides Paris P. Tekkis Thanos Athanasiou Sanjay Purkayastha Paraskevas Paraskeva Ara W. Darzi Alexander G. Heriot | 2006 | Annals of Surgical Oncology2006，，3： | 3 |
| 8 | Conduit necrosis following esophagectomy: An up-to-date literature review显示文摘Esophageal conduit ischaemia and necrosis is an uncommon but devastating complication of esophagectomy and remains one of the most challenging issues in surgical practice. The incidence, time interval to develop symptoms, and clinical presentation are highly variable with no predictable pattern. Evidence comes from case reports and case series rather than randomized controlled trials.We describe the issues surrounding conduit necrosis affecting the stomach,jejunum and colon as an esophageal replacement and the advantages,disadvantages and challenges of each type of reconstruction. Diagnosis is challenging for the most experienced surgeon. Upper gastrointestinal endoscopy and computed tomography thorax with both oral and intravenous contrast is the gold standard. Management, either conservative or interventional is also a difficult decision. Management options include conservative treatment and more aggressive treatments such as stent insertion, surgical debridement and repair of the esophagus using jejunum, colon or a musculocutaneous flap. In spite of recent advances in surgical techniques, there is no reliable strategy to manage esophageal conduit necrosis. Our review covers the pathophysiology and clinical significance of esophageal necrosis while highlighting current techniques of prevention, diagnosis and treatment of this life-threatening condition. | Antonios Athanasiou Mairead Hennessy Eleftherios Spartalis Benjamin H L Tan Ewen A Griffiths | 2019 | World Journal of Gastrointestinal Surgery2019，11，3： | 2 |
| 9 | Laparoscopic assisted distal gastrectomy for early gastric cancer: Is it an alternative to the open approach?显示文摘 | Danny Yakoub Thanos Athanasiou Paris Tekkis George B. Hanna | 2008 | Surgical Oncology2008，，4： | 2 |
| 10 | The role of endo scopic biopsy and third ventriculostomy in the management of pineal region tumors显示文摘 | Pople IK Athanasiou TC Sandeman DR | 2001 | Br J Neurosurg2001，15，4： | 1 |
| 11 | Comparison of the extent and severity of coronary artery disease in patients with acute myocardial infarction with and without microalbuminuria显示文摘 | Loannis L Athanasis K Gevrgios L | 2004 | Am J Cardiol2004，94，： | 1 |
| 12 | Improving culture conditions for tem- poromandibular joint disc tissue engineering显示文摘 | Johns DE Athanasiou KA | 2007 | Cells Tissues Organs2007，185，4： | 1 |
| 13 | Quantitativeassessment of breast lesion viscoelasticity: initial clinical results using supersonic shear imaging显示文摘 | Tanter M Bercoff J Athanasiou A | 2008 | Ultrasound Med Bioi2008，34，9： | 1 |
| 14 | Serological and molecular investigation into the role of wild birds in the epidemiology of West Nile virus in Greece显示文摘 | Valiakos G Touloudi A Athanasiou LV | 2012 | Virel J2012，9，： | 1 |
| 15 | Precision of in vivo spectrophotometric colour evaluation of natural teeth显示文摘 | Karamouzos A Papadopoulos M A Kolokithas G Athanasiou A E | 2007 | J Oral Rehabil2007，34，： | 1 |
| 16 | Sterilization,toxicity,b iocompatibility and clinical applications of poly-lactic acid /polyglycolic acid copolymers显示文摘 | Athanasiou KA Niederauer GG Agrawal CM | | 0，，02： | 1 |
| 17 | Minimal in- ternal fixation augmented by small wire transfixion frames for high-energy tibial plateau fractures显示文摘 | KATSENIS D ATHANASIOU V MEGAS P | 2005 | J Orthop Trauma2005，19，4： | 1 |
| 18 | G-CSF-primed hematopoietic stem cells or G-CSF per se accelerate recovery and improve survival after liver injury, predominantly by promoting endogenous repair programs 显示文摘 | Yannaki E Athanasiou E Xagorari A | 2005 | Exp Hematol2005，33，： | 1 |
| 19 | Evaluation of three growth factors for TMJ disc tissue engineering显示文摘 | Detamore MS Athanasiou KA | 2005 | Ann Biomed Eng2005，33，3： | 1 |
| 20 | Does mini- mally invasive vein harvesting technique affect the quali- ty of the conduit for coronary revascularization? 显示文摘 | Aziz O Athanasiou T Panesar S S | 2005 | Ann Thorac Surg2005，80，6： | 1 |
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