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| 1 | Mental and physical symptoms associated with lower social support for patients with hepatitis C显示文摘AIM: To systematically examine the impact of the hepatitis C virus (HCV) diagnosis on patients' level of social support in a large-scale study. METHODS: Patients evaluated and treated for HCV in a tertiary referral center were enrolled in a cross-sectional study. Demographic data, functional and emotional status as measured by the Hospital Anxiety and Depression Scale (HAD) and the Sickness Impact Profile (SIP), severity of liver disease, mode of acquisition, and physical and psychiatric comorbidities were collected from patients or abstracted from the medical record. All participants completed a semi-structured interview, addressing questions of social support. RESULTS: A total of 342 patients (mean age 45.2 years; 37% women) were enrolled. Ninety-two (27%) patients described lower levels of support by family and friends. Nearly half of the participants (45%) noted the loss of at least one relationship due to the disease. Fears related to transmitting the disease (25%) were common and often associated with ignorance or even discrimination by others (19%). Nearly one fifth of the patients did not share information about their disease with others to avoid being stigmatized. Lower levels of social support were significantly associated with living alone, being unemployed, being excluded from antiviral therapy, having psychiatric comorbidities, contracting HCV through intravenous drug use, having high levels of anxiety and depression as measured by the HAD and negative mood state as measured by the SIP. Patients reporting lower levels of social support also noted more physical symptoms as measured by the SIP. CONCLUSION: Patients with hepatitis C often face significant social problems, ranging from social isolation to familial stress. The most common concerns reflect a limited insight of patients and their relatives and friends about the disease, the risk factors for its spread, and about potential consequences. Our data suggest that educational interventions targeting support persons and the stressors identified in our findings may lessen or alleviate the social strains patients with hepatitis C experience. | Julie A Blasiole Laura Shinkunas Douglas R LaBrecque Robert M Arnold Susan L Zickmund | 2006 | World Journal of Gastroenterology2006，12，29： | 5 |
| 2 | 急性缺血性卒中的机械取栓治疗:ESO、ESMINT、ESNR和EAN共同支持的2014/2015 ESO-卡罗林斯卡卒中更新会议共识声明显示文摘这份卒中后机械取栓治疗共识声明的原始版本于2014年11月16—18日在斯德哥尔摩召开的欧洲卒中组织(European Stroke Organisation, ESO)-卡罗林斯卡卒中更新会议期间得到批准。根据会议安排,在2015年利用新的临床试验数据对该声明进行了更新。2015年2月,在瑞士伯尔尼召开的ESO冬季培训会期间组织了面对面会议对共识声明进行修订,然后通过电子邮件交换意见,最终版本得到各学会的认可。推荐意见与原始版本一致,证据等级更新到2015年2月20日为止,在2015年5月15日获得确认。ESO-卡罗林斯卡卒中更新会议的目的在于总结卒中治疗研究的最新进展并探讨如何将这些最新研究结果应用于临床实践。共识会议选择了一些议题进行讨论,与会者草拟一份共识声明并进行讨论。该声明接受了ESO指南委员会的指导。这份共识声明包括对急性卒中后机械取栓治疗的推荐意见,得到欧洲卒中组织ESO、欧洲神经微创治疗学会(European Society of Minimally Invasive Neurological Therapy, ESMINT)、欧洲神经放射学学会(European Society of Neuroradiology, ESNR)和欧洲神经病学学会(European Academy of Neurology, EAN)的支持。 | Nils Wahlgren Tiago Moreira Patrik Michel Thorsten Steiner Olav Jansen Christophe Cognard Heinrich P Mattle Wim van Zwam Staffan Holmin Turgut Tatlisumak Jesper Petersson Valeria Caso Werner Hacke Mikael Mazighi Marcel Arnold Urs Fischer Istvan Szikora Laurent Pierot Jens Fiehler Jan Gralla Franz Fazekas Kennedy R Lees 高洁 徐格林 | 2016 | 国际脑血管病杂志2016，24，1： | 5 |
| 3 | Preoperative chemoradiotherapy and postoperative chemotherapy with fluorouracil and oxaliplatin versus fluorouracil alone in locally advanced rectal cancer: initial results of the German CAO/ARO/AIO-04 randomised phase 3 trial显示文摘 | Claus R?del Torsten Liersch Heinz Becker Rainer Fietkau Werner Hohenberger Torsten Hothorn Ullrich Graeven Dirk Arnold Marga Lang-Welzenbach Hans-Rudolf Raab Heiko Sülberg Christian Wittekind Sergej Potapov Ludger Staib Clemens Hess Karin Weigang-K?hler G | 2012 | Lancet Oncology2012，，7： | 2 |
| 4 | Buckling,post-buckling and crippling of shallow curved composite plates with edge stiffeners显示文摘 | Arnold R R Yoo S Y Mayers J | 1985 | AIAA1985，23，5： | 2 |
| 5 | An objective method for grading ultrasound images of carotid artery plague显示文摘 | Arnold A Taylor P Poston R | 2001 | Ultasound Med Biol2001，27，8： | 2 |
| 6 | Increase in perforinpositive peripheral blood lymphocytes in extrinsic and intrinsic asthma 显示文摘 | Arnold V Balkow S Staats R | 2000 | Am J Respir Crit Care Med2000，161，1： | 1 |
| 7 | Genetic variation in growth and typhoon resistance in Eucalyptus pellita in southwestern China 显示文摘 | Luo J Arnold R J Aken K | 2006 | Australian Forestry2006，69，： | 1 |
| 8 | Contrastenhanced transcranial colour-coded duplex sonography in ischemic cerebrovascular disease显示文摘 | Baumgartner R Arnold M Gonner F | 1997 | Stroke1997，28，： | 1 |
| 9 | Improved performance of an electrically initiated HF laser显示文摘 | ARNOLD G P WENZEL R G | 1973 | IEEE J Quantum Electron1973，9，4： | 1 |
| 10 | Experiments with rasp bars and threshing drums,some factors affecting performance显示文摘 | Arnold R E | 1964 | Journal of Agricultural Engineering Research1964，，9： | 1 |
| 11 | The Measurement of Selection on Correlated Characters 显示文摘 | LANDE R ARNOLD S J | 1983 | Evolution1983，37，6： | 1 |
| 12 | Diagnostic laparoscopy 显示文摘 | Schneider A R Eickhoff A Arnold J C | 2001 | Endoscopy2001，33，1： | 1 |
| 13 | Validation of the SWAT model on a large river basin with point and nonpoint sources 显示文摘 | SANTHI C ARNOLD J G WILLIAMS J R | 2011 | Journal of the American Water Resources Association2011，37，： | 1 |
| 14 | Continental scale simulation of the hydrologic balance显示文摘 | Arnold J G R Srinivasan R S Muttiah | 1999 | Journal of American Water Resources Association1999，35，5： | 1 |
| 15 | Die bedeutung einiger einflubgroben auf die arbeit der schlagleistentrommel显示文摘 | Arnold R E | 1964 | Grundlagen Der Landtechnik1964，14，： | 1 |
| 16 | A cell-loss concealment technique for MPEG-2 coded video 显示文摘 | ZHANG J Arnold J F Frater M R | 2000 | IEEE Transactions on Circuits and Systems for Video Technology2000，10，4： | 1 |
| 17 | Identification of the major site of apolipoprotein B modification by advanced glycosylation end products blocking uptake by the low density lipoprotein receptor显示文摘 | Bucala R Mitchell R Arnold K | 1995 | J Biol Chem1995，270，10： | 1 |
| 18 | Early management in poor grade aneurysm patients显示文摘 | Nowak G Schwachenwald R Arnold H | 1994 | Acta Neurochir(Wien)1994，126，1： | 1 |
| 19 | Cytokin(IJ-8,IJ-6,TNF-alpha) and soluble TNF receptor-I release from human peripheral blood mononuclear cells after respiratory syncytial virus infection显示文摘 | Arnold R Konig B Galatti H | 1995 | Immunology1995，85，3： | 1 |
| 20 | Locoregional cancer treatment with magnetic drug targeting 显示文摘 | ALEXIOU C ARNOLD W KLEIN R J | 2000 | Cancer Res2000，60，23： | 1 |
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