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| 1 | Function of longitudinal vs circular muscle fibers in esophageal peristalsis, deduced with mathematical modeling显示文摘We summarize from previous works the functions of circular vs. longitudinal muscle in esophageal peristaltic bolus transport using a mix of experimental data, the conservation laws of mechanics and mathematical modeling. Whereas circular muscle tone generates radial closure pressure to create a local peristaltic closure wave, longitudinal muscle tone has two functions, one physiological with mechanical implications, and one purely mechanical. Each of these functions independently reduces the tension of individual circular muscle fibers to maintain closure as a consequence of shortening of longitudinal muscle locally coordinated with increasing circular muscle tone. The physiological function is deduced by combining basic laws of mechanics with concurrent measurements of intraluminal pressure from manometry, and changes in cross sectional muscle area from endoluminal ultrasound from which local longitudinal shortening (LLS) can be accurately obtained. The purely mechanical function of LLS was discovered from mathematical modeling of peristaltic esophageal transport with the axial wall motion generated by LLS. Physiologically, LLS concentrates circular muscle fibers where closure pressure is highest. However, the mechanical function of LLS is to reduce the level of pressure required to maintain closure. The combined physiological and mechanical consequences of LLS are to reduce circular muscle fiber tension and power by as much as 1/10 what would be requiredfor peristalsis without the longitudinal muscle layer, a tremendous benefit that may explain the existence of longitudinal muscle fiber in the gut. We also review what is understood of the role of longitudinal muscle in esophageal emptying, reflux and pathology. | James G Brasseur Mark A Nicosia Anupam Pal Larry S Miller | 2007 | World Journal of Gastroenterology2007，13，9： | 4 |
| 2 | Energy efficient zone division multihop hierarchical clustering algorithm for load balancing in wireless sensor network显示文摘 | ASHIM K G ANUPAM K B DR M A K | 2011 | International Journal of Advanced Computer Science and Application2011，2，12： | 1 |
| 3 | Effect of partial weight-supported treadmill gait training on balance in patients with parkinson disease 显示文摘 | Mohan G Talakad NS Anupam G | 2014 | PM&R2014，6，1： | 1 |
| 4 | Copper quantum clusters in protein matrix:potential sensor of Pb2+ion显示文摘 | NIRMAL G ANUPAM G BOOTHARAJU M S | 2011 | Analytical Chemistry2011，83，： | 1 |
| 5 | Identification and eharacterisation of headspaee volatiles of fish miso,a Japanese fish meat based fermented paste,with special emphasis on effect of fish species and meat washing显示文摘 | Anupam G Kazufumi O Toshiaki O | 2010 | Food Chemistry2010，120，2： | 1 |
| 6 | APACHE Ⅱ predicts longterm survival in COPD patients admirted to a general medical ward 显示文摘 | Anupam G Richard GP Benjamin L | 2003 | JGIM2003，18，10： | 1 |
| 7 | Post-stroke balance training: Role of force platform with visual feedback technique显示文摘 | Abhishek S Arun B T Anupam G | 2009 | J Neurosci2009，287，12： | 1 |
| 8 | Identification and characterisation of headspace volatiles of fish miso, a Japanese fish meat based fermented paste, with special emphasis on effect of fish species and meat washing 显示文摘 | Anupam G Kazufumi O Toshiaki O | 2010 | Food Chem2010，120，2： | 1 |
| 9 | A direct antigen heterologous enzyme imrnunoassay for measuring progesterone in serum without using displacer显示文摘 | Anupam Bsau Tulsidas G Shrivastav Saumert Kumar Maltra | 2006 | Steroids2006，71，： | 1 |
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