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14篇 您的检索式:作者名="ANASTASIO M A"
    题名 作者 年代 出处 被引量
1Data redundancy and reduced-scan reconstruction in reflectivity tomography显示文摘Pan X Zou Y Anastasio M A 2003IEEE Transactions on Image Processing2003,12,7:1
2Comments on the filter back projection algorithm, range condition, and the pseudo reverse solmion 显示文摘Anastasio M A Pan X C Clarkson E 2001IEEE Trans Med Imag2001,20,6:1
3Not all arrestins are created equal: Therapeutic implications of the functional diversity of the β-arrestins in the heart显示文摘The two ubiquitous, outside the retina, G protein-coupled receptor(GPCR)adapter proteins, β-arrestin-1 and-2(also known as arrestin-2 and-3,respectively), have three major functions in cells: GPCR desensitization, i.e.,receptor decoupling from G-proteins; GPCR internalization via clathrin-coated pits; and signal transduction independently of or in parallel to G-proteins. Bothβ-arrestins are expressed in the heart and regulate a large number of cardiac GPCRs. The latter constitute the single most commonly targeted receptor class by Food and Drug Administration-approved cardiovascular drugs, with about onethird of all currently used in the clinic medications affecting GPCR function.Since β-arrestin-1 and-2 play important roles in signaling and function of several GPCRs, in particular of adrenergic receptors and angiotensin II type 1 receptors,in cardiac myocytes, they have been a major focus of cardiac biology research in recent years. Perhaps the most significant realization coming out of their studies is that these two GPCR adapter proteins, initially thought of as functionally interchangeable, actually exert diametrically opposite effects in the mammalian myocardium. Specifically, the most abundant of the two β-arrestin-1 exerts overall detrimental effects on the heart, such as negative inotropy and promotion of adverse remodeling post-myocardial infarction(MI). In contrast, β-arrestin-2 is overall beneficial for the myocardium, as it has anti-apoptotic and antiinflammatory effects that result in attenuation of post-MI adverse remodeling,while promoting cardiac contractile function. Thus, design of novel cardiac GPCRligands that preferentially activate β-arrestin-2 over β-arrestin-1 has the potential of generating novel cardiovascular therapeutics for heart failure and other heart diseases.Anastasios Lymperopoulos Shelby L Wertz Celina M Pollard Victoria L Desimine Jennifer Maning Katie A McCrink 2019World Journal of Cardiology2019,11,2:1
4A preliminary investigation of local tomography for megavoltage CT imaging 显示文摘M A Anastasio D Shi X Pan C A Pelizzari and P Munro 2003Med Phys2003,30,:1
5Human leptin induces angiogenesis in vivo显示文摘Stavros A Anastasios J Lambropoulou M 2008Cytokine2008,42,3:1
6Comments on the tilted backprojection algorithm, range conditions and the pseudoinverse solution 显示文摘Anastasio M A Pan Xiaochuan Eric Clarkson 2001IEEE Transactions on Medical Imaging2001,20,6:1
7Feasibility of half-data image reconstruction in 3-D reflectivity tomography with a spherical aperture显示文摘ANASTASIO M A ZHANG J SIDKY E Y 2005IEEE Transactions on Medical Imaging2005,24,:1
8Reducing Intergroup Bias: The Com- mon Ingroup Identity Model 显示文摘Gaertner S L Dovidio J F Anastasio P A Bachman B A Rust M C 1993European Review of Social Psychology1993,,4:1
9Effcient HPLC method for the determination of nicarbazin as dinitrocarbanitide in broiler liver显示文摘CAPURRO E DANAHER M ANASTASIO A 2005Journal of Chromatography B2005,822,:1
10EfficientHPLC method for the determination of nicarbazin,as dinitrocarbani-lide in broiler liver显示文摘CAPURRO E DANAHER M ANASTASIO A 2005J Chromatogr B Analyt Technol Biomed LifeSci2005,822,12:1
11Comments on the filter back projection algorithm,range condition,and the pseudo inverse solution显示文摘Anastasio M A Pan X C Clarkson E 2001IEEE Trans Med Imag2001,20,6:1
12Identification of cow's milk in 'buffalo' cheese by duplex polymerase chain reaction 显示文摘Bottero M T Civera T Anastasio A 2002Food Protection2002,65,:1
13On a limited-view reconstruction problem in diffraction tomography显示文摘Pan X Anastasio M A 2002IEEE Trans on Medical Imaging2002,21,4:1
14New crosslinkable polyimides, polyamides and polyureas derived from 2,4,6-tris(4-aminophenoxy)-s-triazine显示文摘Anastasios P M John A M 1989Eur Polym J1989,25,:1
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