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| 1 | Clinical significance of main pancreatic duct dilation on computed tomography: Single and double duct dilation显示文摘AIM: To study the patients with main pancreatic duct dilation on computed tomography (CT) and thereby to provide the predictive criteria to identify patients at high risk of significant diseases, such as pancreatic cancer, and to avoid unnecessary work up for patients at low risk of such diseases. METHODS: Patients with dilation of the main pancreatic duct on CT at Emory University Hospital in 2002 were identified by computer search. Clinical course and ultimate diagnosis were obtained in all the identified patients by abstraction of their computer database records. RESULTS: Seventy-seven patients were identified in this study. Chronic pancreatitis and pancreatic cancer were the most common causes of the main pancreatic duct dilation on CT. Although the majority of patients with isolated dilation of the main pancreatic duct (single duct dilation) had chronic pancreatitis, one-third of patients with single duct dilation but without chronic pancreatitis had pancreatic malignancies, whereas most of patients with concomitant biliary duct dilation (double duct dilation) had pancreatic cancer. CONCLUSION: Patients with pancreatic double duct dilation need extensive work up and careful followup since a majority of these patients are ultimately diagnosed with pancreatic cancer. Patients with single duct dilation, especially such patients without any evidence of chronic pancreatitis, also need careful follow-up since the possibility of pancreatic malignancy, including adenocarcinoma and intraductal papillary mucinous tumors, is still high. | Mark D Edge Maarouf Hoteit Amil P Patel Xiaoping Wang Deborah A Baumgarten Qiang Cai | 2007 | World Journal of Gastroenterology2007，13，11： | 9 |
| 2 | The HiPIP from the acidophilic AcidithiobaciUus ferrooxidans is correctly processed and, translocated in Escherichia coli, in spite of the periplasm pH difference between these two micro-organisms 显示文摘 | BRUSCELLA P CASSAGNAUD L RATOUCHNIAK J BRASSEUR G LOJOU E AMILS R BONNEFOY V | 2005 | Microbiology2005，151，5： | 1 |
| 3 | Estimating Production Functions Using Inputs to Control for Unobservables显示文摘 | James L Amil P | 2003 | Re- view of Economic Studies2003，70，2： | 1 |
| 4 | The HiPIP from the acidophilic Acidithiobacillus ferrooxidans is correctly processed and translocated in Escherichia coli, in spite of the periplasm pH difference between these two micro-organisms 显示文摘 | BRUSCELLA P CASSAGNAUD L RATOUCHN1AK J BRASSEUR G LOJOU E AMILS R BONNEFOY V | 2005 | Microbiol2005，151，10： | 1 |
| 5 | Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass 显示文摘 | Ducy P Amiling M Takeda S | 2000 | Cell2000，100，： | 1 |
| 6 | Maskless lithography显示文摘 | RAJESH M AMIL P DARIO G | 2005 | Materialstoday2005，8，2： | 1 |
| 7 | 山羊催乳素受体基因型对乳中脂肪酸组成的多效性作用显示文摘哺乳期的乳腺,催乳素(PRL)刺激乳糖合成以及脂肪酸摄取、脂肪生成和甘油三酯的合成。牛催乳素受体(PRLR)基因型和脂肪酸产量之间的关系已有报道,这些报道说明,催乳素对乳腺传输脂质的作用及泌乳期刺激脂质合成的局限性。相反,据我们所知,到目前为止,对于哺乳动物,催乳素受体基因型对乳中脂肪酸含量的影响尚未有研究报道。本研究对马拉格纳和穆尔西亚诺品种山羊的大部分基因编码区域进行了排序。这种方法能够由选择性剪切产生并确定两个长、短mRNA亚型,及c.177T>C,c.1131G>A,c.1201G>Aandc.1355C>T4种单核苷酸多态性(SNPs)。其中有两个非同义SNP位点,即G401R(c.1201G>A)和T452I(c.1355C>T),这些催乳素受体细胞域中的氨基酸的替换在信号转导过程中发挥了重要的作用。对穆尔西亚诺山羊群体乳成分性状的关联分析表明,对棕榈油酸含量影响很大,也表明了对其他脂肪酸也有影响(如棕榈酸、亚油酸)。这些结果与催乳素对乳腺脂质代谢及乳成分多效性影响是一致的。 | Zidi A Serradilla J M Jordana J Carrizosa J Urrutia B Polvillo O González-Redondo P Gallardo D Amills M Fernández-Cabanás V M | 2010 | 饲料博览2010，，9： | 0 |
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