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| 1 | Sarcopenia in heart failure: mechanisms and therapeutic strategies显示文摘长期的心失败(CHF ) 是一个高度流行的条件在之中老并且与可观的病态, institutionalization 和死亡被联系。在它的先进阶段, CHF 被肌肉质量和力量的损失经常伴随。Sarcopenia 是活跃地与大量不利健康结果由于它的协会在最近的年里被学习了的衰老老人症候群。这评论的目标是讨论在 CHF 和 sarcopenia 之间的关系,与分享的 pathophysiological 小径和处理的一个焦点。营养不良,全身的发炎,内分泌的不平衡,和氧化应力看起来连接 sarcopenia 和 CHF。在肌肉发达的水平, ubiquitin proteasome 系统,发信号的 myostatin,和 apoptosis 的改变在 sarcopenia 和 CHF 被描述了并且能在肌肉质量和功能的损失起一个作用。阻碍肌肉在 CHF 病人浪费的前进的可能的治疗学的策略包括变换血管收缩素的酶禁止者和 β 的蛋白质和维生素 D 补充,结构化的物理锻练,和管理; -blockers。有生长荷尔蒙,睾丸激素,和 ghrelin 的神经质的补充也作为潜在的治疗被讨论。 | Agnese Collamati Emanuele Marzetti Riccardo Calvani Matteo Tosato Emanuela D'Angelo Alex N Sisto Francesco Landi | 2016 | Journal of Geriatric Cardiology2016，13，7： | 25 |
| 2 | Sentinel lymph node radiolocalization in head and neck squamous carcinoma显示文摘 | ALEX J C SASAKI C T KRAG D N | 2000 | Larygoscope2000，110，： | 1 |
| 3 | On the Corrosion Induced Mechanical Degradation for Fifferent Artificial Aging Conditions of 2024 Aluminum Alloy显示文摘 | Alex opoulos N D | 2009 | Materials Science and Engineering A2009，520，12： | 1 |
| 4 | The gamma-probe-guidod resection of radio labeled primary lymph nodes显示文摘 | Alex J C Krag D N | 1996 | Surg Oncol N Am1996，5，1： | 1 |
| 5 | Gamma-probe guided localization of lymph nodes 显示文摘 | Alex J C Krag D N | 1993 | Surg Oncol1993，2，： | 1 |
| 6 | Experimental and Theoretical Studies of Corrosion Induced Mechanical Properties Degradation of Aircraft 2024 Aluminum alloy显示文摘 | Alex opoulos N D Papanikos P | 2008 | Materials Science and Engineering A2008，498，12： | 1 |
| 7 | Nanoshell tubes of ferroelectric lead zirconate titanate and barium titanate显示文摘 | Luo Y Szafraniak I Zakharov N D Nagarajan V Steinhart M Wehrspohn R B Wendorff J H Ramesh R Alexe M | 2003 | Appl Phys Lett2003，83，： | 1 |
| 8 | SuperspreadingDriven by Marangoni Flow显示文摘 | ALEX D N DARSH T W ANOOP C | 2002 | Advances in Colloid and InterfaceScience2002，96，： | 1 |
| 9 | Ferroelectric lead zirconate titanate and barium titanate nanotubes显示文摘 | Luo Y Szafraniak I Nagarajan V Wehrspohn R B Steinhart M Wendorff J H Zakharov N D Ramesh R Alexe M | 2003 | Ferroelectrics2003，59，： | 1 |
| 10 | Ferroelectrie nanotubes显示文摘 | Morrison F D Luo Y Szafraniak I Nagarajan V Wehrspoh R B Steinhart M Wendorff J H Zakharov N D Mishina E D Vorotilov K A Sigov A S Nakabayshi S Alexe M Ramesh R Scott J F | 2003 | Rev Adv Mater Sci2003，4，： | 1 |
| 11 | Gamma probe guided localization of lymoh nodes显示文摘 | Alex J C Krag D N | 1993 | Surg Oncol1993，2，3： | 1 |
| 12 | Gamma-probe guided localization of lymph nodes显示文摘 | Alex J C Krang D N | 1993 | Surg Oncol1993，2，2： | 1 |
| 13 | Development of a gamma compensated boron lined ionisation chamber for reactor safety and control applications显示文摘 | ALEX M PRAKASH J S PRASAD D N | 2007 | Nuclear Instruments and Methods in Physics Research A2007，，： | 1 |
| 14 | Surgical resection and radiolocalization of the sentinal lymph node in breast cancer using a gamma probe显示文摘 | Krag D N Weaver D L Alex J C | 1993 | Surgical Oncology1993，2，6： | 1 |
| 15 | Portal vein ligation accelerates tumor growth in ligated,but not contralateral lobes显示文摘AIM: To investigate the mechanisms of liver growth and atrophy after portal vein ligation (PVL) and its effects on tumor growth. METHODS: Mice were subjected to PVL, partial hepatectomy, or sham surgery. The morphological alterations, activation of transcription factors, and expression of cytokines and growth factors involved in liver regeneration were evaluated. In a separate set of experiments, murine colorectal carcinoma cells were injected via the portal vein and the effect of each operation on liver tumor growth was studied. RESULTS: Liver regeneration after PVL and partial hepatectomy were very similar. In ligated lobes, various cytokines, transcription factors and regulatory factors were signifi cantly upregulated compared to nonligated lobes after PVL. Atrophy in ligated lobes was a result of early necrosis followed by later apoptosis. Tumor growth was signifi cantly accelerated in ligated compared to non-ligated lobes.CONCLUSION: Tumor growth was accelerated in ligated liver lobes and appeared to be a result of increased growth factor expression. | Nozomu Sakai Callisia N Clarke Rebecca Schuster John Blanchard Amit D Tevar Michael J Edwards Alex B Lentsch | 2010 | World Journal of Gastroenterology2010，16，30： | 1 |
| 16 | Gamma-probe guided localization of lymph nodes显示文摘 | Alex J C Krag D N | 1993 | Surg Oncol1993，2，3： | 1 |
| 17 | Superspreading driven by Marangoni flow显示文摘 | ALEX D N DARSH T W ANOOP C | 2002 | Advances in Colloid and interface Science2002，96，： | 1 |
| 18 | Gamma probe guided resection of radiolabeled primarylymph nodes 显示文摘 | Alex J C Krag D N | 1996 | Surg Oncol Clin NAm1996，5，1： | 1 |
| 19 | Surgical resection and radioloealization of the sentinel lymph node in breast cancer using a gamma probe显示文摘 | Krag D N Weaver D L Alex J C | 1993 | Surg Oneol1993，2，： | 1 |
| 20 | Gamma-probe guided localization of lymph nodes显示文摘 | Alex J C Krag D N | 1993 | Surg Oncol1993，2，： | 1 |
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