|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Comparison of pre-treatment and post-treatment use of selenium in retinal ischemia reperfusion injury显示文摘AIM: To investigate the effects of selenium in rat retinal ischemia reperfusion(IR) model and compare pretreatment and post-treatment use.METHODS: Selenium pre-treatment group(n =8) was treated with intraperitoneal(i.p.) selenium 0.5 mg/kg for7 d and terminated 24 h after the IR injury. Selenium posttreatment group( n = 8) was treated with i. p. selenium0.5 mg/kg for 7d after the IR injury with termination at the end of the 7d period. Sham group(n =8) received i.p.saline injections identical to the selenium volume for 7d with termination 24 h after the IR injury. Control group(n =8) received no intervention. Main outcome measures were retina superoxide dismutase(SOD), glutathione(GSH),total antioxidant status(TAS), malondialdehyde(MDA),DNA fragmentation levels, and immunohistological apoptosis evaluation.RESULTS: Compared to the Sham group, selenium pre-treatment had a statistical difference in all parameters except SOD. Post-treatment selenium also resulted in statistical differences in all parameters except the MDA levels. When comparing selenium groups, the pre-treatment selenium group had a statistically higher success in reduction of markers of cell damage such as MDA and DNA fragmentation. In contrast, the post-selenium treatment group had resulted in statisticallyhigher levels of GSH. Histologically both selenium groups succeeded to limit retinal thickening and apoptosis. Pre-treatment use was statistically more successful in decreasing apoptosis in ganglion cell layer compared to post-treatment use.CONCLUSION: Selenium was successful in retinal protection in IR injuries. Pre-treatment efficacy was superior in terms of prevention of tissue damage and apoptosis. | Alper Yazici Hasan Aksit Esin Sogutlu Sari Arzu Yay Haydar Ali Erken Dilek Aksit Harun Cakmak Kamil Seyrek Sitki Samet Ermis | 2015 | International Journal of Ophthalmology(English edition)2015，8，2： | 3 |
| 2 | Non-dipper hypertension is associated with slow coronary flow among hypertensives with normal coronary angiogram显示文摘 | Aksit E Gursul E Aydin F | 2016 | Cardiovasc J Afr2016，27，： | 1 |
| 3 | Discussing aspects of AOP显示文摘 | Elrad T Aksit M Kiczales G | 2001 | Communication of the ACM2001，44，10： | 1 |
| 4 | Mumps seroprevalence in an unvaccinated population in lzmir, turkey 显示文摘 | AKSIT S EGEMEN A OZACAR T | 2000 | Acta Paediatr2000，89，3： | 1 |
| 5 | Plasma and urinary endothelin-1 concentrations in asphyxiated newbors显示文摘 | Tekin N Dinleyici E C Aksit M A | 2007 | Neuro Endocrinol Lett2007，28，3： | 1 |
| 6 | Effects of geometry on brush seal pressure and flow fields- I: front plate configurations 显示文摘 | DOGU Y AKSIT M F | 2006 | Journal of Turbomachinery2006，128，： | 1 |
| 7 | Effects of geometry on brush seal pressure and flow fields- II: backing plate configurations 显示文摘 | DOGU Y AKSIT M F | 2006 | Journal of Turbomachinery2006，128，： | 1 |
| 8 | Brush seal temperature distribution a- nalysis显示文摘 | Dogu Y Aksit M F | 2006 | Journal of Engineering for Gas Turbines and Power2006，128，3： | 1 |
| 9 | Diagnostic values of lipid and lipoprotein levels in late onset neonatal sepsis显示文摘 | Yildiz B Ucar B Aksit A | 2009 | Scand J Infect Dis2009，41，： | 1 |
| 10 | Brush seal temperature distribution analy- sis显示文摘 | DOGU Y AKSIT M F | 2006 | Journal of Engineering for Gas Turbines and Power2006，128，3： | 1 |
| 11 | Determination of antioxidant activities of various extracts and essential oil compositions of Thymus praecox subsp, skorpilii var, skorpilii 显示文摘 | Ozen T Demirtas I Aksit H | 2011 | Food Chemistry2011，124，1： | 1 |
| 12 | Discussing aspects of AOP 显示文摘 | Elrad T Aksit M Kiczales G | 2001 | Communications of the ACM2001，44，10： | 1 |
| 13 | Low-dose intradermal administration of recombinant hepatitis B vaccine in children:5-year followup study显示文摘 | Kurugol Z Erensoy S Aksit S | 2001 | Vaccine2001，19，2829： | 1 |
| 14 | Low-dose intradermal versus intramuscular administration of recombinant hepatitis B vaccine:a comparison of immunogenicity in infants and preschool children显示文摘 | Egemen A Aksit S Kurugol Z | 1998 | Vaccine1998，16，16： | 1 |
| 15 | Electromagnetic and electrical properties of coated cotton fabric with barium ferrite doped polyaniline film显示文摘 | AKSIT A C ONAR N EBEOGLUGIL M F | | 0，，01： | 1 |
| 16 | Structural,electrical,and electromagnetic properties of cotton fabrics coated with polyaniline and polypyrrole显示文摘 | ONAR N AKSIT A C EBEOGLUGIL M F | | 0，，04： | 1 |
| 17 | Discussing aspects of AOP显示文摘 | ELRAD T AKSIT M M KICZALES G | 2001 | Communication of the ACM2001，44，10： | 1 |
| 18 | Low-dose intradermal administration of recombinant hepatitis B vaccine in children: 5-year follow-up study显示文摘 | Kurugol Z Erensoy S Aksit S | 2001 | Vaccine2001，19，2829： | 1 |
| 19 | A lumped parameter analysis of powder injection mouling显示文摘 | Aksit M F Lee D | 1995 | Powder Metall1995，31，4： | 1 |
| 20 | Advanced seals for industrial turbine applications显示文摘 | Mahmut M Aksit F | 2002 | Journal of Propulsion and Power2002，18，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员