|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Exercise-induced increase in brain-derived neurotrophic factor in human Parkinson's disease:a systematic review and metaanalysis显示文摘Background:Animal models of exercise and Parkinson’s disease(PD)have found that the physiologic use of exercise may interact with the neurodegenerative disease process,likely mediated by brain derived neurotrophic factor(BDNF).No reviews so far have assessed the methodologic quality of available intervention studies or have bundled the effect sizes of individual studies on exercise-induced effects on BDNF blood levels in human PD.Research design and methods:We searched MEDLINE,EMBASE,Cochrane Library,PsycINFO and PubMed from inception to June 2017.Results:Data aggregated from two randomized controlled trials and four pre-experimental studies with a total of 100 ambulatory patients with idiopathic PD(Hoehn/Yahr≤3)found improvements in BDNF blood concentration levels in all 6 studies(two RCTs and 4 pre-experimental studies).Pooled BDNF level change scores from the 2 RCTs resulted in a significant homogeneous summary effect size(Standardized Mean Difference 2.06,95% CI 1.36 to 2.76),and a significant heterogeneous SES for the motor part of the UPDRS-Ⅲ examination(MD-5.53,95% CI-10.42 to-0.64).Clinical improvements were noted in all studies using a variety of outcome measures.Limitations:The evidence-base consists primarily of small studies with low to moderate methodological quality.Conclusions:This review provides preliminary evidence for the effectiveness of physical exercise treatments for persons with PD on BDNF blood levels.Further research is needed. | Mark A.Hirsch Erwin E.H.van Wegen Mark A.Newman Patricia C.Heyn | 2018 | Translational Neurodegeneration2018，7，1： | 6 |
| 2 | A case–control study of unilateral and bilateral breast carcinoma patients显示文摘 | Lisa A.Newman Ayesgul A.Sahin Melissa L.Bondy Nadeem Q.Mirza George S.Vlastos Gary J.Whitman HeatherBrown Thomas A.Buchholz Mong‐HongLee S. EvaSingletary | 2001 | Cancer2001，，10： | 1 |
| 3 | New advances in three dimensional transient electromagnetic inversion显示文摘 | Gregory A.Newman MichaelCommer | 2004 | Geophysical Journal International2004，，1： | 1 |
| 4 | A new chelonibiid from the Miocene of Zanzibar (Eastern Africa) sheds light on the evolution of shell architecture in turtle and whale barnacles (Cirripedia: Coronuloidea)显示文摘The fossil history of turtle and whale barnacles(Coronuloidea:Chelonibiidae,Platylepadidae,Coronulidae and†Emersoniidae)is fragmentary and has only been investigated in part.Morphological inferences and molecular phylogenetic analyses on extant specimens suggest that the roots of whale barnacles(Coronulidae)are to be found among the chelonibiid turtle barnacles,but the hard-part modifications that enabled early coronuloids to attach to the cetacean skin are still largely to be perceived.Here,we reappraise a fossil chelonibiid specimen from the Miocene of insular Tanzania that was previously referred to the living species Chelonibia caretta.This largely forgotten specimen is here described as the holotype of the new species†Chelonibia zanzibarensis.While similar to C.caretta,†C.zanzibarensis exhibits obvious external longitudinal parietal canals occurring in-between external longitudinal parietal septa that abut outwards to form T-shaped flanges,a character so far regarded as proper of the seemingly more derived Coronulidae and Platylepadidae.Along with these features,the presence of a substrate imprint on the shell exterior indicates that†C.zanzibarensis grasped its host’s integument in much the same way as coronulids and platylepadids,albeit without the development of macroscopic parietal buttresses and bolsters.Thin section analyses of the inner parietal architecture of some extant and extinct coronuloids conclusively demonstrate that vestiges of comparable external parietal microstructures are present in some living members of Chelonibiidae.This observation strengthens the unity of Coronuloidea while significantly contributing to our understanding of the evolution of the coronuloid shell structure in adapting to a diverse spectrum of hosts. | Alberto COLLARETA William A.NEWMAN Giulia BOSIO Giovanni COLETTI | 2022 | Integrative Zoology2022，17，1： | 0 |
| 5 | 答复:新成果证明不同模型的公开讨论是正确的显示文摘1000年前,犹太哲人写道:“学者间的争论可增进智慧”。与之相比,Schweig等人要求对选择与他们在新马德里地震带(NMSZ)高危险性模型不同的模型要十分谨慎。我们发现这有点不可思议。 | A.Newman S.Stein J.Weber J.Engeln Ailin Mao T.Dixon 何玉林 | 1999 | 世界地震译丛1999，，5： | 0 |
| 6 | The“Tears of the Virgin”at Lakes Entrance,southeast Australia were made by the intertidal barnacle Chthamalus antennatus(Cirripedia:Thoracica)and cyanobacteria显示文摘Curious eroded depressions,most resembling an eye shedding an elongate tear,are found in gently sloping,intertidal,carbonate-rich arenite outcropping on the sea coast near Lakes Entrance,Victoria,southeast Australia.The depressions,known locally as“Tears of the Virgin,”are evidently formed by multiple generations of a barnacle,Chthamalus antennatus Darwin,1854 in association with cyanobacteria.While the round part of a depression offers the barnacle a modicum of protection from impacts during high tides,it is also partially inhabited by cyanobacteria,which extend into and tend to fill the elongate tear.As such,this appears to be the first case of mutualism between a higher invertebrate and cyanobacteria,with the cyanobacteria reducing the barnacle’s risk of desiccation while receiving metabolic wastes from it during low tides.It is also the first record of a balanomorph barnacle eroding calcareous arenite beneath its shell,the net effect of which would be expected to reduce its adhesion to the substrate.However,the siliceous residue,resulting from the barnacle’s dissolution of the more than 80%of the calcite-rich sedimentary rock,is sequestered in delicate folds on the inside of the shell wall as it grows.A brief review of cirripedes capable of excavation includes the first photographic documentation of excavation of a mollusc shell by a verrucomorph. | John S.BUCKERIDGE William A.NEWMAN | 2017 | Integrative Zoology2017，12，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员