|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Esophageal tissue engineering:A new approach for esophageal replacement显示文摘A number of congenital and acquired disorders require esophageal tissue replacement.Various surgical techniques,such as gastric and colonic interposition,are standards of treatment,but frequently complicated by stenosis and other problems.Regenerative medicine approaches facilitate the use of biological constructs to replace or regenerate normal tissue function.We review the literature of esophageal tissue engineering,discuss its implications,compare the methodologies that have been employed and suggest possible directions for the future.Medline,Embase,the Cochrane Library,National Research Register and ClinicalTrials.gov databases were searched with the following search terms:stem cell and esophagus,esophageal replacement,esophageal tissue engineering,esophageal substitution.Reference lists of papers identified were also examined and experts in this field contacted for further information.All full-text articles in English of all potentially relevant abstracts were reviewed.Tissue engineering has involved acellular scaffolds that were either transplanted with the aim of being repopulated by host cells or seeded prior to transplantation.When acellular scaffolds were used to replace patch and short tubular defects they allowed epithelial and partial muscular migration whereas when employed for long tubular defects the results were poor leading to an increased rate of stenosis and mortality.Stenting has been shown as an effective means to reduce stenotic changes and promote cell migration,whilst omental wrapping to induce vascularization of the construct has an uncertain benefit.Decellularized matrices have been recently suggested as the optimal choice for scaffolds,but smart polymers that will incorporate signalling to promote cell-scaffold interaction may provide a more reproducible and available solution.Results in animal models that have used seeded scaffolds strongly suggest that seeding of both muscle and epithelial cells on scaffolds prior to implantation is a prerequisite for complete esophageal replacement.Novel approaches need to be designed to allow for peristalsis and vascularization in the engineered esophagus.Although esophageal tissue engineering potentially offers a real alternative to conventional treatments for severe esophageal disease,important barriers remain that need to be addressed. | Giorgia Totonelli Panagiotis Maghsoudlou Jonathan M Fishman Giuseppe Orlando Tahera Ansari Paul Sibbons Martin A Birchall Agostino Pierro Simon Eaton Paolo De Coppi | 2012 | World Journal of Gastroenterology2012，18，47： | 5 |
| 2 | Accurate characteriza- tion of extravascular lung water in acute respiratory distress syn- drome显示文摘 | Berkowitz D M Danai P A Eaton S | 2008 | Crit Care Med2008，36，6： | 1 |
| 3 | 5,1O-meth ylenetetrahydrofotate reductase 677 and 1298 polymorphisms,folate intake,and microsatellite instability in colon cancer显示文摘 | EATON A M SANDLER R CARETHERS J M | 2005 | Cancer Epidemiol Biomarkers Prev2005，14，8： | 1 |
| 4 | Components, formulations, solutions, evaluation, and application of comprehensive combustion models显示文摘 | Eaton A M Smoot L D Hill S C | 1999 | Progress in Energy and Combustion Science1999，25，4： | 1 |
| 5 | Inflammatory response in children after laparoscopic vs open Nissen fundoplication:rando- mized controlled trial显示文摘 | McHoney M Eaton S Wade A | 2005 | Pediatr Surg2005，40，6： | 1 |
| 6 | Stereo selective sulphate conjugation of lbutamol by human lung and bronchial epithelial cells显示文摘 | Eaton E A Walle U K Wilson H M | 1996 | B r J Clin Pham acol1996，41，： | 1 |
| 7 | Components, formulations, solutions, evaluation, and application of comprehensive combustion models显示文摘 | A M Eaton L D Smoot S C Hill C N Eatough | 1999 | Progress in Energy and Combustion Science1999，，25： | 1 |
| 8 | Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy显示文摘 | Cameron N E Eaton S E Cotter M A | 2001 | Diabetologia2001，44，11： | 1 |
| 9 | Investigation of factors affecting chan- nelling in fixed bed solid fuel combustion using CFD显示文摘 | Duffy N T M Eaton J A | 2013 | Corn bustion and Flame2013，160，10： | 1 |
| 10 | Occurrence and suitability of sucralose as an indicator compound of wastewater loading to surface waters in urbanized regions 显示文摘 | Oppenheimer J Eaton A Badruzzaman M | 2011 | Water Res2011，45，13： | 1 |
| 11 | Role of the JAK/STAT signaling pathway in diabetic nephropathy显示文摘 | Marrero M B Banes-Berceli A K Stern D M Eaton D C | 2006 | Am J Physiol2006，290，4： | 1 |
| 12 | Cysteinyl leukotriene signaling through perinuclear CysLT ( 1 ) receptors on vascular smooth muscle cells transduces nuclear calcium signaling and alterations of gene expression显示文摘 | Eaton A Nagy E Pacanh M | 2012 | J Mol Med2012，90，10： | 1 |
| 13 | The modeling and prediction and experimental evaluation of gear pump meshing pressures with particular reference to aero-engine fuel pumps显示文摘 | Eaton M Keogh P S Edge K A | 2006 | Proceedings of the Institution of Mechanical Engineers2006，220，5： | 1 |
| 14 | Inter- mittent testicular torsion: diagnostic features and man- agement outcomes显示文摘 | Eaton S H Cendron M A Estrada C R | 2005 | J Urol2005，174，42： | 1 |
| 15 | Size dependent platelet subpopulations: relationship of platelet volume to ultrastrueture, enzymatic activity, and function显示文摘 | THOMPSON C B EATON K A PRINCIOTTA S M | 1982 | Br J Haematol1982，50，3： | 1 |
| 16 | The X-ray structure of a hemipteran ecdysone receptor ligandbinding domain:comparison with a lepidopteran ecdysone receptor ligand-binding domain and implications for insecticide design显示文摘 | Carmichael J A Lawrence M C Graham L D Pilling P A Epa V C Noyce L Lovrecz G Winkler D A PawlakSkrzecz A Eaton R E Hannan G N and Hill R J | | 0，，： | 1 |
| 17 | Measurement and modeling of liquid film thickness evolution in stratified two phase microchannel flows 显示文摘 | Steinbrenner J E Hidrovo C H Wang F M Vigneron S Lee E S Kramer T A Cheng C H Eaton J K Goodson K E | 2007 | Applied Thermal Engineering2007，27，： | 1 |
| 18 | Characterizing the unfolded states of proteins using single-molecule FRET spectroscopy and molecular simulations显示文摘 | Merchant K A Best R B Louis J M Gopich I V Eaton W A | | 0，，： | 1 |
| 19 | Management of pediatric inguinal hernias in the era of laparoscopy : results of an international survey 显示文摘 | Zani A Eaton S Hoellwarth M | 2014 | Eur J Pediatr Surg2014，24，1： | 1 |
| 20 | Occurrence and suitability of sucralose as an indicator compound of wastewater loading to surface waters in urbanized regions显示文摘 | OPPENHEIMER J EATON A BADRUZZAMAN M | 2011 | Water Res2011，45，13： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员