Urinary Creatinine-Skeletal Muscle Mass Method:A Prediction Equation Based on Computerized Axial Tomography

查看全文 作　　者：ZI-MIAN WANG;YUN-GAO SUN;AND STEVEN B. HEYMSFIELD (Department of Medicine, Obesity Research Center, St. Luke’s-Roosevelt Hospital, Columbia University College of Physicians and Surgeons,Amsterdam Ave. 14C New York, N. Y., USA)(Obesity Research Center, We 出　　处：《Biomedical and Environmental Sciences》索引1996年第9卷第2期,共6页 摘　　要：A classic body composition method is estimation of total body skeletal muscle mass (SM, kg) from 24 h urinary creatinine excretion (Cr, g). Two types of prediction equations were suggested: one assumes a constant SM/Cr ratio; and the other assumes a highly variable SM/Cr ratio. We explored these two extreme possibilities by measuring SM with whole-body computerized axial tomography and collecting Cr during meat-free dietary conditions in 12 healthy young men. Prediction equations were developed in the men that fit these two equation types, SM = 21.8×Cr (SD and CV of SM/Cr ratio, 1.3 kg and 6.0%,respectively) and SM = 18.9 × Cr + 4.1 (r = 0.92, p = 2.55 × 10-5, and SEE = 1.9 kg). The validity of each model is reviewed. This is the first investigation of Cr-SM method using modern techniques for quantifying total body SM 关 键 词：尿样肌酐酸-骨骼肌质量法 CT 预测公式 Cr-SM 临床应用