Neuropathic pain after bilateral sagittal split osteotomy:management and prevention

查看全文 作　　者：Jimoh Olubanwo [1,2]Agbaje;Ivo [3]Lambrichts;Reinhilde [1]Jacobs;Constantinus [1,3]Politis 机构地区：[1]Department of Imaging and Pathology,Faculty of Medicine,Catholic University of Leuven,3000 Leuven,Belgium;[2]Department of Oral and Maxillofacial Surgery,St.John’s Hospital,3600 Genk,Belgium;[3]Faculty of Medicine,Morphology Research Group,Hasselt University,3590 Diepenbeek,Belgium 出　　处：《Plastic and Aesthetic Research》索引2015年第2卷第1期,共5页 摘　　要：Neuropathic pain is characterized by spontaneous and provoked pain and other signs reflecting neural damage.Aberrant regeneration following peripheral nerve lesions leaves neurons unusually sensitive and prone to spontaneous pathological activity,abnormal excitability and heightened sensitivity to stimuli.This review covers the current understanding of neuropathic pain after bilateral sagittal split osteotomy(BSSO)of the lower jaw.The reported incidence of neuropathic pain after mandibular osteotomies is less than 1%,while the incidence in patients with iatrogenic inferior alveolar nerve(IAN)injuries during BSSO can be as high as 45%.The factors which modulate the healing process toward neuropathic pain during or after nerve damage have not yet been elucidated.Patients at highest risk for developing post-BSSO neuropathic pain are older than 45 years and have undergone procedures involving IAN compression,partial severance,or complete discontinuity of the lingual nerve with a proximal stump neuroma,patients with nerve injury repair delayed longer than 12 months and patients with chronic illnesses that compromise healing or increase risk for peripheral neuropathy.Although neuropathic pain tends to be long-lasting,some patients can recover completely.Preventive measures include risk assessment prior to surgery,prevention of nerve damage during surgery,and early repair of nerve injury. 关 键 词：Bilateral sagittal split osteotomy INCIDENCE MANAGEMENT neuropathic pain risk factor