Asymmetric Catalytic α-Selective Allylation of Ketones with Allyltrifluoroborates Using Dual-Functional Chiral In^(Ⅲ)/N,N'-Dioxide Complex

查看全文 作　　者：Xiaoxue [1]Tang;Zhishan [1]Su;Qianchi [1]Lin;Lili [1]Lin;Shunxi [1]Dong;Xiaoming [1]Feng

机构地区：[1]Key Laboratory of Green Chemistry&Technology,Ministry of Education,College of Chemistry,Sichuan University,Chengdu,Sichuan 610064,China

出　　处：《Chinese Journal of Chemistry》索引2022年第40卷第15期,共6页

基　　金：This work is supported by the National Natural Science Foundation of China(No.21890723);Sichuan University(2020SCUNL204). 摘　　要：Comprehensive Summary Asymmetric catalytic allylation of halo-substituted ketones and ketoesters was accomplished to yield a number of homoallylic tertiary alcohols in excellent reactivity and enantioselectivity.In the presence of chiral In^(Ⅲ)/N,N-dioxide catalyst,unusual α-selective allylation ofγ-substituted potassium allyltrifluoroborates to ketones was demonstrated.The control experiments and DFT calculation reveal that chiral In^(Ⅲ)/N,N'-dioxide catalyst plays dual-tasking roles:the formation of allylindium species via transmetalation and Lewis acid activation.Apossiblereaction pathwaywas provided tounderstandα-selectivity overy-selectivity. 关键词：ALLYLATION Potassium allyltrifluoroborate KETONES INDIUM Regioselectivity and enantioselectivity

相关文献

参考文献（49）
引证文献（3）
耦合文献（4）

参考文献(49)

引证文献(3)

耦合文献(4)

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

Asymmetric Catalytic α-Selective Allylation of Ketones with Allyltrifluoroborates Using Dual-Functional Chiral In^(Ⅲ)/N,N'-Dioxide Complex

参考文献(49)

引证文献(3)

耦合文献(4)

用户提示