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Postoperative sleep disorders and their potential impacts on surgical outcomes

查看全文 作  者:Sanketh [1]Rampes;Katie [1]Ma;Yasmin Amy [1]Divecha;Azeem [2]Alam;Daqing [2]Ma 高影响力作者 机构地区:[1]Facuity of Life Sciences&Medicine,King's College London,London SEI 1UL,UK;[2]Anaesthetics,Pain Medicine and Intensive Care,Department of Surgery and Cancer,Faculty of Medicine,Imperial College London,Chelsea and Westminster Hospital,London SW109NH,UK.高影响力机构 出  处:《The Journal of Biomedical Research》索引2020年第34卷第4期,共10页高影响力期刊 摘  要:Postoperative sleep disturbance is a common occurrence with significant adverse effects on patients including delayed recovery,impairment of cognitive function,pain sensitivity and cardiovascular events.The development of postoperative sleep disturbance is multifactorial and involves the surgical inflammatory response,the severity of surgical trauma,pain,anxiety,the use of anesthetics and environmental factors such as nocturnal noise and light levels.Many of these factors can be managed perioperatively to minimize the deleterious impact on sleep.Pharmacological and non-pharmacological treatment strategies for postoperative sleep disturbance include dexmedetomidine,zolpidem,melatonin,enhanced recovery after surgery(ERAS) protocol and controlling of environmental noise and light levels.It is likely that a combination of pharmacological and non-pharmacological therapies will have the greatest impact;however,further research is required before their use can be routinely recommended. 关 键 词:POSTOPERATIVE sleep disturbance surgical outcomes
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