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Serological Survey of Zika Virus in Humans and Animals in Dejiang Prefecture, Guizhou Province,China

查看全文 作　　者：LI [1,2]Fan;ZHOU Jing [3]Zhu;ZHOU [4]Lei;FU Shi [1,2]Hong;TIAN Zhen [3]Zao;WANG [4]Qi;SHAO [1,2]Nan;LI [4]Dan;HE [1,2]Ying;LEI Wen [1,2]Wen;TANG Guang [3]Peng;LIANG Guo [1,2]Dong;WANG Ding [3]Ming;ZHANG Yan [4]Ping;WANG Huan [1,2]Yu 高影响力作者 机构地区：[1]NHC Key Laboratory of Biosafety,National Institute for Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China;[2]State Key Laboratory for Infectious Disease Prevention and Control,Chinese Center for Disease Control and Prevention,Beijing 102206,China;[3]Guizhou Center for Disease Control and Prevention,Guiyang 550004,China;[4]Public Health Emergency Center,Chinese Center for Disease Control and Prevention,Beijing 102206,China高影响力机构 出　　处：《Biomedical and Environmental Sciences》索引2019年第32卷第12期,共6页高影响力期刊 基　　金：supported by the National Science and Technology Major Project [2018ZX10713-002,2017ZX10104001,2018ZX10711001];National key research and development project [2017YFC1200505,2016YFC1200905];the Development Grant of State Key Laboratory of Infectious Disease Prevention and Control [2015SKLID505,2014SKLID103] 摘　　要：Objective The current outbreak of Zika virus(ZIKV)poses a severe threat to human health.Two ZIKV strains were isolated from mosquitoes collected from the Dejiang prefecture in China in 2016,which was the first isolation of ZIKV in nature in China.Methods In this study,serum samples were collected from 366 healthy individuals and 104 animals from Dejiang prefecture in 2017,and the plaque reduction neutralization test(PRNT)was used to evaluate the seroprevalence of ZIKV.Results None of the 366 residents from whom the samples were collected were seropositive for ZIKV.None of the 11 pigs from whom the samples were collected were seropositive for ZIKV,while 1 of 63(1.59%)chickens and 2 of 30(6.67%)sheep were seropositive for ZIKV.Conclusions The extremely low seropositivity rate of ZIKV antibodies in animals in the Dejiang prefecture,Guizhou province in this study indicates that ZIKV can infect animals;however,there is a low risk of ZIKV circulating in the local population. 关 键 词：Zika Virus Serological survey Humans ANIMALS China Plague reduction neutralization test
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