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A Review on Pharmacological and Analytical Aspects of Naringenin

查看全文 作  者:Kanika [1]Patel;Gireesh Kumar [2]Singh;Dinesh Kumar [2]Patel 高影响力作者 机构地区:[1]G.L.A Institute of Pharmaceutical Research,Mathura,India;[2]Department of Pharmaceutics,Institute of Technology,Banaras Hindu University,Varanasi-221005,India高影响力机构 出  处:《Chinese Journal of Integrative Medicine》索引2018年第24卷第7期,共10页高影响力期刊 摘  要:Flavonoids are a widely distributed group of phytochemicals having benzo-pyrone nucleus, and more than 4,000 different flavonoids have been described and categorized into flavonols, flavones, flavanones, isoflavones, catechins and anthocyanidins. Flavonoids occurs naturally in fruits, vegetables, nuts, and beverages such as coffee, tea, and red wine, as well as in medical herbs. Flavonoids are responsible for the different colors of plant parts and are important constituents of the human diet. Flavanoids have different pharmacological activities, such as antioxidant, anti-allergic, antibacterial, anti-inflammatory, antimutagenic and anticancer activity. Naringenin belongs to the flavanones and is mainly found in fruits(grapefruit and oranges) and vegetables. Pharmacologically, it has anticancer, antimutagenic, anti-inflammatory, antioxidant, antiproliferative and antiatherogenic activities. Naringenin is used for the treatments of osteoporosis, cancer and cardiovascular diseases, and showed lipid-lowering and insulin-like properties. In the present review, detailed pharmacological and analytical aspects of naringenin have been presented, which revealed the impressive pharmacological profile and the possible usefulness in the treatment of different types of diseases in the future. The information provided in this communication will act as an important source for development of effective medicines for the treatment of various disorders. 关 键 词:药理学 评论 抗氧化剂 骨质疏松症 类脂化合物 黄酮醇 黄烷酮 原子核
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