Cell-specific mineralocorticoid receptors:future therapeutic targets for stroke?

查看全文 作　　者：Quynh [1]N.Dinh;Grant [1]R.Drummond;Christopher [1]G.Sobey;Sophocles [2]Chrissobolis

机构地区：[1]Vascular Biology & Immunopharmacology Group,Cardiovascular Disease Program and Department of Pharmacology,Biomedicine Discovery Institute,Monash University;[2]Department of Pharmaceutical and Biomedical Sciences,Raabe College of Pharmacy,Ohio Northern University

出　　处：《Neural Regeneration Research》索引2016年第11卷第8期,共2页

基　　金：supported by a postdoctoral fellowship from the National Health and Medical Research Council (NHMRC) of Australia;the Foundation for High Blood Pressure Research Australia (to SC);grants from the NHMRC and the National Heart Foundation of Australia 摘　　要：The mineralocorticoid receptor(MR),well known to be expressed in renal epithelial cells where it is important in fluid and electrolyte homeostasis,has aldosterone as one of its main agonists.Much research in the last 10–15 years indicates that MRs are also expressed outside of the kidney,including in the brain,vasculature and heart,where they contribute to the pathophysiology of disease(Dinh et al.,2012; 关键词：激素受体细胞特异性皮质肾小管上皮细胞脑卒中治疗盐病理生理学

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Cell-specific mineralocorticoid receptors:future therapeutic targets for stroke?

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