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Study of retinal vessel oxygen saturation in ischemic and non-ischemic branch retinal vein occlusion

查看全文 作　　者：Lei-Lei [1]Lin;Yan-Min [1]Dong;Yao [1]Zong;Qi-Shan [1]Zheng;Yue [1]Fu;Yong-Guang [1]Yuan;Xia [1]Huang;Garrett [2]Qian;Qian-Ying [1]Gao 高影响力作者 机构地区：[1]Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat-sen University;[2]School of Optometry and Vision Science, The University of New South Wales高影响力机构 出　　处：《International Journal of Ophthalmology(English edition)》索引2016年第9卷第1期,共9页高影响力期刊 基　　金：Supported by the National Science&Technology Pillar Program of the Twelfth Five-year Plan(2012BAI08B04);Open Research Funds of the State Key Laboratory of Ophthalmology 摘　　要：AIM:To explore how oxygen saturation in retinal blood vessels is altered in ischemic and non-ischemic branch retinal vein occlusion(BRVO).·METHODS:Fifty BRVO eyes were divided into ischemic(n=26)and non-ischemic(n=24)groups,based on fundus fluorescein angiography.Healthy individuals(n=52 and n=48,respectively)were also recruited as controls for the two groups.The mean oxygen saturations of the occluded vessels and central vessels were measured by oximetry in the BRVO and control groups.·RESULTS:In the ischemic BRVO group,the occluded arterioles oxygen saturation(Sa O2-A,106.0%±14.3%),instead of the occluded venule oxygen saturation(Sa O2-V,60.8%±9.4%),showed increases when compared with those in the same quadrant vessels(Sa O2-A,86.1%±16.5%)in the contralateral eyes(P<0.05).The oxygen saturations of the central vessels showed similar trends with those of the occluded vessels.In the non-ischemic BRVO group,the occluded and central Sa O2-V and Sa O2-A showed no significant changes.In both the ischemic and non-ischemic BRVOs,the central Sa O2-A was significantly increased when compared to healthy individuals.·CONCLUSION:Obvious changes in the occluded and central Sa O2-A were found in the ischemic BRVO group,indicating that disorders of oxygen metabolism in the arterioles may participate in the pathogenesis of ischemic BRVO. 关 键 词：组织缺氧 局部缺血 OXIMETRY 氧浸透 分叉网膜的静脉吸藏
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