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Effects of cereal fiber on bowel function: A systematic review of intervention trials

查看全文 作  者:Jan de [1]Vries;Paige E [2,3]Miller;Kristin [4]Verbeke 高影响力作者 机构地区:[1]De Vries Nutrition Solutions Inc.;[2]Center for Epidemiology, Biostatistics, and Computational Biology, Exponent, Inc.;[3]Nutrition and Food Service, Edward Hines Jr. VA Hospital, Hines;[4]Department of Clinical and Experimental Medicine, KU Leuven高影响力机构 出  处:《World Journal of Gastroenterology》索引2015年第21卷第29期,共12页高影响力期刊 基  金:Supported by funding from Kellogg Company,Battle Creek,MI,United States 摘  要:AIM: To comprehensively review and quantitatively summarize results from intervention studies that examined the effects of intact cereal dietary fiber on parameters of bowel function. METHODS: A systematic literature search was conducted using Pub Med and EMBASE. Supplementary literature searches included screening reference lists from relevant studies and reviews. Eligible outcomes were stool wet and dry weight, percentage water in stools, stool frequency and consistency, and total transit time. Weighted regression analyses generated mean change(± SD) in these measures per g/d of dietary fiber. RESULTS: Sixty-five intervention studies among generally healthy populations were identified. A quantitative examination of the effects of non-wheat sources of intact cereal dietary fibers was not possible due to an insufficient number of studies. Weighted regression analyses demonstrated that each extra g/d of wheat fiber increased total stool weight by 3.7 ± 0.09 g/d(P < 0.0001; 95%CI: 3.50-3.84), dry stool weight by 0.75 ± 0.03 g/d(P < 0.0001; 95%CI: 0.69-0.82), and stool frequency by 0.004 ± 0.002 times/d(P = 0.0346; 95%CI: 0.0003-0.0078). Transittime decreased by 0.78 ± 0.13 h per additional g/d(P < 0.0001; 95%CI: 0.53-1.04) of wheat fiber among those with an initial transit time greater than 48 h.CONCLUSION: Wheat dietary fiber, and predominately wheat bran dietary fiber, improves measures of bowel function. 关 键 词:Comprehensive review DIETARY FIBER WHEAT BRAN CEREAL BOWEL function
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