Hepatic inflammatory pseudotumor presenting in an 8-year-old boy: A case report and review of literature

查看全文 作　　者：Hussa Al-[1]Hussaini;Haya [2]Azouz;Ahmed Abu-[2]Zaid

机构地区：[1]Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Centre;[2]College of Medicine, Alfaisal University

出　　处：《World Journal of Gastroenterology》索引2015年第21卷第28期,共9页

摘　　要：Hepatic inflammatory pseudotumors are uncommon benign lesions.Accurately diagnosing hepatic inflammatory pseudotumor can be very challenging because the clinical presentation and radiological appearances are nonspecific and cannot be certainly distinguished from malignant neoplastic processes.Herein,we present a case of hepatic IPT in an 8-yearold boy who presented to clinic with a 3-mo history of a tender hepatic mass,fever of unknown origin,and9-kg weight loss.The physical examination was notable for tender hepatomegaly.Laboratory investigations were notable for a normal hepatic profile and elevated erythrocyte sedimentation rate and C-reactive protein.A T2-attenuated magnetic resonance imaging scan of the abdomen showed a 4.7 cm x 4.7 cm x 6.6cm,contrast-enhancing,hyper-intense,well-defined lesion involving the right hepatic lobe.In view of the unremitting symptoms,tender hepatomegaly,thrombosed right hepatic vein,nonspecific radiological findings,and high suspicion of a deep-seated underlying infection or malignancy,a right hepatic lobectomy was recommended.Microscopically,the hepatic lesion exhibited a mixture of inflammatory cells(histiocytes,plasma cells,mature lymphocytes,and occasional multinucleated giant cells) in a background of dense fibrous tissue.Immunohistochemically,the cells stained negative for SMA,ALK-1,CD-21 and CD-23,diffusely positive for CD-68,and focally positive for lgG4.The final histopathological diagnosis was consistent with hepatic IPT.At the postoperative 4-mo follow-up,the patient was asymptomatic without radiological evidence of recurrence. 关键词：INFLAMMATORY PSEUDOTUMOR Inflammatorymyofibroblastic tumor HEPATIC Liver

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Hepatic inflammatory pseudotumor presenting in an 8-year-old boy: A case report and review of literature

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