Experimental Study of Effect of Perfluorohexyloctane to Retina

查看全文 作　　者：Chunfang Li, Xiaoyan Ding, Lin Lu, Guanguang Feng, Huling ZhengZhongshan Ophthalmic center, Sun Yet-san University, Guangzhou, 510060 , China

出　　处：《Eye Science》索引2002年第18卷第1X期,共5页

摘　　要：Objective: To investigate the effect of perfluorohexvloctane to the retina of rabbit eyes.Methods: Perfluoroh-exyloctane (experimental group) or BSS(control group) intovitreous cavities of fifteen vitrectomized New Zealand white rabbits. A slit-lampbiomicroscope and an indirect ophthalmoscope were used to examine all the eyes pre- andpostoperation. Histopathological examination was performed after the rabbits weresacrificed. Results:Perfluorohexyloctane was injected into the vitreous cavity forming a single largeclear globe. No retinal detachment and cataract were found. The edema of outer plexiformlayer was significant, and then get thin, inner nuclear layer and ganglion cell bodies hada darker cytop: lasm and nucleoplasm. Conclusions: Perfluorohexyloctane in vitreous cavity had significant side effects on retinaAs a silicone solvent, it should be removed out completely after injection. We don′trecommend to use it as a new intraocular temponade. 关键词：视网膜 F6H8 玻璃体替代物玻璃体切除

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Experimental Study of Effect of Perfluorohexyloctane to Retina

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